Decreased sensitivity of tristetraprolin-deficient cells to p38 inhibitors suggests the involvement of tristetraprolin in the p38 signaling pathway
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The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritisCytoplasmic localization of tristetraprolin involves 14-3-3-dependent and -independent mechanismsDestabilization of vascular endothelial growth factor mRNA by the zinc-finger protein TIS11bMK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decayFunctional cloning of BRF1, a regulator of ARE-dependent mRNA turnover.The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase BThe Herpesvirus saimiri small nuclear RNAs recruit AU-rich element-binding proteins but do not alter host AU-rich element-containing mRNA levels in virally transformed T cellsThe roles of TTP and BRF proteins in regulated mRNA decayChaperone Hsp27, a novel subunit of AUF1 protein complexes, functions in AU-rich element-mediated mRNA decayTristetraprolin and its family members can promote the cell-free deadenylation of AU-rich element-containing mRNAs by poly(A) ribonucleaseThe control of inflammation via the phosphorylation and dephosphorylation of tristetraprolin: a tale of two phosphatasesPhosphorylation of human tristetraprolin in response to its interaction with the Cbl interacting protein CIN85ZFP36L1 is regulated by growth factors and cytokines in keratinocytes and influences their VEGF productionBRF1 protein turnover and mRNA decay activity are regulated by protein kinase B at the same phosphorylation sitesZFP36L1 negatively regulates erythroid differentiation of CD34+ hematopoietic stem cells by interfering with the Stat5b pathwayThe p38 MAPK pathway inhibits tristetraprolin-directed decay of interleukin-10 and pro-inflammatory mediator mRNAs in murine macrophagesExpression and purification of recombinant tristetraprolin that can bind to tumor necrosis factor-alpha mRNA and serve as a substrate for mitogen-activated protein kinasesRNA-destabilizing factor tristetraprolin negatively regulates NF-kappaB signalingFunctional analysis of KSRP interaction with the AU-rich element of interleukin-8 and identification of inflammatory mRNA targets.Phosphorylation of p40AUF1 regulates binding to A + U-rich mRNA-destabilizing elements and protein-induced changes in ribonucleoprotein structure.Regulation of A + U-rich element-directed mRNA turnover involving reversible phosphorylation of AUF1.Identification of the anti-inflammatory protein tristetraprolin as a hyperphosphorylated protein by mass spectrometry and site-directed mutagenesisPhosphorylation site analysis of the anti-inflammatory and mRNA-destabilizing protein tristetraprolin.The potential of p38 MAPK inhibitors to modulate periodontal infections.Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatasesTreatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression.The MAP kinase-activated protein kinase 2 (MK2) contributes to the Shiga toxin-induced inflammatory responseIdentification of a major phosphopeptide in human tristetraprolin by phosphopeptide mapping and mass spectrometry.Myocardial knockdown of mRNA-stabilizing protein HuR attenuates post-MI inflammatory response and left ventricular dysfunction in IL-10-null mice.Neuronal ELAV proteins enhance mRNA stability by a PKCalpha-dependent pathwayRNA-binding protein Csx1 mediates global control of gene expression in response to oxidative stress.Polyubiquitinated tristetraprolin protects from TNF-induced, caspase-mediated apoptosisExpression, purification, and biochemical characterization of the antiinflammatory tristetraprolin: a zinc-dependent mRNA binding protein affected by posttranslational modifications.Immunological characterization of tristetraprolin as a low abundance, inducible, stable cytosolic proteinNegative feedback regulation of MKK6 mRNA stability by p38alpha mitogen-activated protein kinasePhosphorylation of tristetraprolin by MK2 impairs AU-rich element mRNA decay by preventing deadenylase recruitment.Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich elementThe biosynthesis characteristics of TTP and TNF can be regulated through a posttranscriptional molecular loopNitric oxide activation of Erk1/2 regulates the stability and translation of mRNA transcripts containing CU-rich elementsp38 Mitogen-activated protein kinase-dependent and -independent signaling of mRNA stability of AU-rich element-containing transcripts
P2860
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P2860
Decreased sensitivity of tristetraprolin-deficient cells to p38 inhibitors suggests the involvement of tristetraprolin in the p38 signaling pathway
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
@zh-hans
2001年学术文章
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2001年学术文章
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2001年學術文章
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name
Decreased sensitivity of trist ...... n in the p38 signaling pathway
@ast
Decreased sensitivity of trist ...... n in the p38 signaling pathway
@en
Decreased sensitivity of trist ...... n in the p38 signaling pathway
@nl
type
label
Decreased sensitivity of trist ...... n in the p38 signaling pathway
@ast
Decreased sensitivity of trist ...... n in the p38 signaling pathway
@en
Decreased sensitivity of trist ...... n in the p38 signaling pathway
@nl
prefLabel
Decreased sensitivity of trist ...... n in the p38 signaling pathway
@ast
Decreased sensitivity of trist ...... n in the p38 signaling pathway
@en
Decreased sensitivity of trist ...... n in the p38 signaling pathway
@nl
P2093
P2860
P3181
P356
P1476
Decreased sensitivity of trist ...... n in the p38 signaling pathway
@en
P2093
D Campbell
E A Kennington
E Carballo
P J Blackshear
P2860
P304
42580-42587
P3181
P356
10.1074/JBC.M104953200
P407
P50
P577
2001-09-06T00:00:00Z