Increased ability for selection of zidovudine resistance in a distinct class of wild-type HIV-1 from drug-naive persons - Test2 - elhamkhani - TriplyDB

Increased ability for selection of zidovudine resistance in a distinct class of wild-type HIV-1 from drug-naive persons

Increased ability for selection of zidovudine resistance in a distinct class of wild-type HIV-1 from drug-naive persons

http://www.wikidata.org/entity/Q28363547

about

Minority HIV-1 drug resistance mutations are present in antiretroviral treatment-naïve populations and associate with reduced treatment efficacy Persistence of transmitted HIV-1 drug resistance mutations associated with fitness costs and viral genetic backgrounds Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: an individual-patient- and sequence-level meta-analysis Epidemiological Surveillance of HIV-1 Transmitted Drug Resistance in Spain in 2004-2012: Relevance of Transmission Clusters in the Propagation of Resistance Mutations Time trends in drug resistant HIV-1 infections in the United Kingdom up to 2009: multicentre observational study A fossil record of zidovudine resistance in transmitted isolates of HIV-1 Using drug exposure for predicting drug resistance - A data-driven genotypic interpretation tool Characterization of the patterns of drug-resistance mutations in newly diagnosed HIV-1 infected patients naïve to the antiretroviral drugs.Deciphering Evolutionary Mechanisms Between Mutualistic and Pathogenic Symbioses Transmitted antiretroviral drug resistance among acute and recent HIV infections in North Carolina from 1998 to 2007 Characterization of drug-resistance mutations in HIV type 1 isolates from drug-naive and ARV-treated patients in Bulgaria.Prevalence of transmitted HIV-1 antiretroviral resistance among patients initiating antiretroviral therapy in Brazil: a surveillance study using dried blood spots.A multicenter study of initiation of antiretroviral therapy and transmitted drug resistance in antiretroviral-naive adolescents and young adults with HIV in New York City High viremia and low level of transmitted drug resistance in anti-retroviral therapy-naïve perinatally-infected children and adolescents with HIV-1 subtype C infection Persistence of frequently transmitted drug-resistant HIV-1 variants can be explained by high viral replication capacity.A novel genetic pathway of human immunodeficiency virus type 1 resistance to stavudine mediated by the K65R mutation.Major HIV resistance mutations in untreated Romanian patients.Infectivity and replication capacity of drug-resistant human immunodeficiency virus type 1 variants isolated during primary infection Transmitted human immunodeficiency virus type 1 carrying the D67N or K219Q/E mutation evolves rapidly to zidovudine resistance in vitro and shows a high replicative fitness in the presence of zidovudine.Japanese external quality assessment program to standardize HIV-1 drug-resistance testing (JEQS2010 program) using in vitro transcribed RNA as reference material.Clinical management of HIV drug resistance.Consensus drug resistance mutations for epidemiological surveillance: basic principles and potential controversies.Mutations in the connection domain of HIV-1 reverse transcriptase increase 3'-azido-3'-deoxythymidine resistance Transmitted HIV Drug Resistance Is High and Longstanding in Metropolitan Washington, DC HIV-1 protease and reverse transcriptase mutations for drug resistance surveillance.Nucleoside reverse transcriptase inhibitor resistance mutations associated with first-line stavudine-containing antiretroviral therapy: programmatic implications for countries phasing out stavudine HIV-1 drug resistance mutations: an updated framework for the second decade of HAART Active methamphetamine use is associated with transmitted drug resistance to non-nucleoside reverse transcriptase inhibitors in individuals with HIV infection of unknown duration Minority human immunodeficiency virus type 1 variants in antiretroviral-naive persons with reverse transcriptase codon 215 revertant mutations.Clinical significance of human immunodeficiency virus type 1 replication fitness.Comparison of algorithms that interpret genotypic HIV-1 drug resistance to determine the prevalence of transmitted drug resistance Aptamer-based therapeutics: new approaches to combat human viral diseases Impact of nelfinavir resistance mutations on in vitro phenotype, fitness, and replication capacity of human immunodeficiency virus type 1 with subtype B and C proteases.Evolutionary pathways of transmitted drug-resistant HIV-1.Mechanism of HIV antiretroviral drugs progress toward drug resistance.Molecular determinants of multi-nucleoside analogue resistance in HIV-1 reverse transcriptases containing a dipeptide insertion in the fingers subdomain: effect of mutations D67N and T215Y on removal of thymidine nucleotide analogues from blocked DN Combination of drugs and drug-resistant reverse transcriptase results in a multiplicative increase of human immunodeficiency virus type 1 mutant frequencies Commonly Transmitted HIV-1 Drug Resistance Mutations in Reverse-Transcriptase and Protease in Antiretroviral Treatment-Naive Patients and Response to Regimens Containing Tenofovir Disoproxil Fumarate or Tenofovir Alafenamide.HIV-1 subtypes and drug resistance profiles in a cohort of heterosexual patients in Istanbul, Turkey.Trends in prevalence of HIV-1 drug resistance in Thailand 2009-2010.

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P2860

Increased ability for selection of zidovudine resistance in a distinct class of wild-type HIV-1 from drug-naive persons

http://www.wikidata.org/entity/Q28363547

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2001 nî lūn-bûn

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2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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Proceedings of the National Academy of Sciences of the United States of America

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Increased ability for selectio ...... HIV-1 from drug-naive persons

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H Weinstock

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J G Garcia-Lerma

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K Blumoff

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S Nidtha

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W Heneine

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P2860

Zidovudine-resistant human immunodeficiency virus selected by passage in cell culture

In vitro selection of variants of human immunodeficiency virus type 1 resistant to 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine

Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)

Switch to unusual amino acids at codon 215 of the human immunodeficiency virus type 1 reverse transcriptase gene in seroconvertors infected with zidovudine-resistant variants.

Evidence of a role for the Q151L mutation and the viral background in development of multiple dideoxynucleoside-resistant human immunodeficiency virus type 1

Comparative fitness of multi-dideoxynucleoside-resistant human immunodeficiency virus type 1 (HIV-1) in an In vitro competitive HIV-1 replication assay

Relative replication fitness of a high-level 3'-azido-3'-deoxythymidine-resistant variant of human immunodeficiency virus type 1 possessing an amino acid deletion at codon 67 and a novel substitution (Thr-->Gly) at codon 69.

A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1

Multiple drug resistance to nucleoside analogues and nonnucleoside reverse transcriptase inhibitors in an efficiently replicating human immunodeficiency virus type 1 patient strain.

Human immunodeficiency virus fitness in vivo: calculations based on a single zidovudine resistance mutation at codon 215 of reverse transcriptase

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13907-12

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10.1073/PNAS.241300698

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24

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98

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2001-11-20T00:00:00Z

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11655189

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11698656

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61140

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