Molecular determinants of multi-nucleoside analogue resistance in HIV-1 reverse transcriptases containing a dipeptide insertion in the fingers subdomain: effect of mutations D67N and T215Y on removal of thymidine nucleotide analogues from blocked DN
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K70Q adds high-level tenofovir resistance to "Q151M complex" HIV reverse transcriptase through the enhanced discrimination mechanismThe L76V mutation in HIV-1 protease is potentially associated with hypersusceptibility to protease inhibitors Atazanavir and Saquinavir: is there a clinical advantage?Structures of reverse transcriptase pre- and post-excision complexes shed new light on HIV-1 AZT resistanceUnderstanding HIV resistance, fitness, replication capacity and compensation: targeting viral fitness as a therapeutic strategy.Insertions in the human immunodeficiency virus type 1 protease and reverse transcriptase genes: clinical impact and molecular mechanisms.Thymidine analogue resistance suppression by V75I of HIV-1 reverse transcriptase: effects of substituting valine 75 on stavudine excision and discrimination.Chain-terminating dinucleoside tetraphosphates are substrates for DNA polymerization by human immunodeficiency virus type 1 reverse transcriptase with increased activity against thymidine analogue-resistant mutants.Mechanisms involved in the selection of HIV-1 reverse transcriptase thumb subdomain polymorphisms associated with nucleoside analogue therapy failure.Structural Aspects of Drug Resistance and Inhibition of HIV-1 Reverse Transcriptase.Xenotropic murine leukemia virus-related virus is susceptible to AZT.Altered strand transfer activity of a multiple-drug-resistant human immunodeficiency virus type 1 reverse transcriptase mutant with a dipeptide fingers domain insertion.The L74V mutation in human immunodeficiency virus type 1 reverse transcriptase counteracts enhanced excision of zidovudine monophosphate associated with thymidine analog resistance mutations.Clinical, virological and biochemical evidence supporting the association of HIV-1 reverse transcriptase polymorphism R284K and thymidine analogue resistance mutations M41L, L210W and T215Y in patients failing tenofovir/emtricitabine therapyAmino acid residues in HIV-2 reverse transcriptase that restrict the development of nucleoside analogue resistance through the excision pathway.
P2860
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P2860
Molecular determinants of multi-nucleoside analogue resistance in HIV-1 reverse transcriptases containing a dipeptide insertion in the fingers subdomain: effect of mutations D67N and T215Y on removal of thymidine nucleotide analogues from blocked DN
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Molecular determinants of mult ...... tide analogues from blocked DN
@en
type
label
Molecular determinants of mult ...... tide analogues from blocked DN
@en
prefLabel
Molecular determinants of mult ...... tide analogues from blocked DN
@en
P2093
P2860
P356
P1476
Molecular determinants of mult ...... tide analogues from blocked DN
@en
P2093
Antonio Mas
Blanca M Vázquez-Alvarez
Luis Menéndez-Arias
Sandra Franco
Tania Matamoros
P2860
P304
24569-24577
P356
10.1074/JBC.M312658200
P407
P577
2004-03-25T00:00:00Z