Quinone reductase inhibitors block SAPK/JNK and NFkappaB pathways and potentiate apoptosis
about
Beta-lapachone suppresses radiation-induced activation of nuclear factor-kappaBRole of caspases in dexamethasone-induced apoptosis and activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase in human eosinophilsSulindac compounds facilitate the cytotoxicity of β-lapachone by up-regulation of NAD(P)H quinone oxidoreductase in human lung cancer cellsATP regulates the differentiation of mammalian skeletal muscle by activation of a P2X5 receptor on satellite cellsA novel mitogen-activated protein kinase phosphatase is an important negative regulator of lipopolysaccharide-mediated c-Jun N-terminal kinase activation in mouse macrophage cell lines.Reactive oxygen species from NAD(P)H:quinone oxidoreductase constitutively activate NF-kappaB in malignant melanoma cells.NAD(P)H quinone oxidoreductase protects TAp63gamma from proteasomal degradation and regulates TAp63gamma-dependent growth arrest.Dicumarol inhibits PDK1 and targets multiple malignant behaviors of ovarian cancer cells.Multiple neurotrophic effects of VEGF on cultured neurons.MAPK signaling and the kidney.Potential chemopreventive agents based on the structure of the lead compound 2-bromo-1-hydroxyphenazine, isolated from Streptomyces species, strain CNS284Novel pathways associated with quinone-induced stress in breast cancer cells.Suppression of NAD(P)H-quinone oxidoreductase 1 enhanced the susceptibility of cholangiocarcinoma cells to chemotherapeutic agents.Inhibition of caspase 3 abrogates lipopolysaccharide-induced nitric oxide production by preventing activation of NF-kappaB and c-Jun NH2-terminal kinase/stress-activated protein kinase in RAW 264.7 murine macrophage cells.Dichotomal effect of the coumadin derivative warfarin on inflammatory signal transduction.A novel arsenical has antitumor activity toward As2O3-resistant and MRP1/ABCC1-overexpressing cell lines.Mitochondrial production of reactive oxygen species mediate dicumarol-induced cytotoxicity in cancer cells.Identification of a hydrogen peroxide-induced PP1-JNK1-Sp1 signaling pathway for gene regulation.Tumor necrosis factor-alpha inhibits aquaporin 5 expression in mouse lung epithelial cells.Transient activation of Jun N-terminal kinases and protection from apoptosis by the insulin-like growth factor I receptor can be suppressed by dicumarol.NAD(P)H:Quinone oxidoreductase activity is the principal determinant of beta-lapachone cytotoxicity.Lipopolysaccharide and proinflammatory cytokines stimulate interleukin-6 expression in C2C12 myoblasts: role of the Jun NH2-terminal kinase.Disruption of planar cell polarity activity leads to developmental biliary defects.Reactive oxygen species regulate signaling pathways induced by M1 muscarinic receptors in PC12M1 cells.Phosphorylation is involved in the activation of metal-regulatory transcription factor 1 in response to metal ions.Expression of NAD(P)H:quinone oxidoreductase 1 in HeLa cells: role of hydrogen peroxide and growth phase.Activation of monocyte cyclooxygenase-2 gene expression by human herpesvirus 6. Role for cyclic AMP-responsive element-binding protein and activator protein-1.Astrocyte protection of neurons: role of transforming growth factor-beta signaling via a c-Jun-AP-1 protective pathway.Genetic deletion of NAD(P)H:quinone oxidoreductase 1 abrogates activation of nuclear factor-kappaB, IkappaBalpha kinase, c-Jun N-terminal kinase, Akt, p38, and p44/42 mitogen-activated protein kinases and potentiates apoptosis.
P2860
Q28274858-DED3D3E2-AF4B-4E89-8D1B-C81CF15E3DC8Q28344818-2721EDFB-83CC-4DCE-88CD-279C2ED34E6FQ28539534-D2160C22-6985-47B2-B3F4-1BD24C6410A7Q28577947-09806AB0-58F5-49AB-8505-CBAD3F3515C4Q30723911-E85B4883-7A25-4CC2-892F-D5170589198EQ31919510-28A20C58-D9C9-4340-8F2E-9BC81D43FB6BQ33627637-E17DE8D5-CE5E-4AFD-9825-634AF6834F9AQ33803278-0BA449D7-7DED-453F-B2CE-A2D2AB97A256Q33888914-FB1E76D7-2DF2-43ED-92BB-C124915B20A8Q34039916-2B7784D1-1C86-4A36-8A9B-8D5E18A359C1Q34440701-B135EC47-65C3-42B5-9CDB-9461061D3AD5Q36673564-36BC307F-7D2D-40E4-B05E-FE99209305D2Q37580906-38D188D5-0D92-4BDE-817F-F3866D573989Q39518600-40E4D79D-A333-4DBC-BB87-4403307D44CFQ39662389-E0C0D858-A069-4EDD-8AE9-45903E6D79CAQ39960419-179FEB53-F4C8-4FAB-8B4E-6FB0E372FC11Q40220387-73583FB8-ADE2-4261-AAE5-A741578FFD9DQ40260459-12D7B004-EE7C-4FB6-B567-4F2AE874DAEFQ40816417-F7F76C8A-DF5B-40C0-91A0-9B4C1EA11D73Q40817283-6CF718B0-AF9A-4872-A090-105BA828ADCCQ40899393-35CE0AE0-A3B2-4281-A61F-F7A43F21061BQ42169148-64FC9EC6-0CB4-49EB-A7C2-04A1C86E6EA8Q42636809-8D166F9C-8D80-40BF-AEE4-77B55F0E3A2BQ43548195-7121EC7F-9E2D-474C-A035-0B72F7ED057AQ43734045-9E470D24-8543-4D95-A74D-0BED659CA5F8Q43744817-A16DD00C-61D5-48AC-BDE9-4936D0F52423Q44030362-BA8A76D1-4944-48DF-8717-E4C619426A86Q44530869-152640F8-8C2F-4DC4-B470-C3FB8E957A68Q53346452-97B47DC1-F9D5-411E-B0E4-BEBC0D7B0A9E
P2860
Quinone reductase inhibitors block SAPK/JNK and NFkappaB pathways and potentiate apoptosis
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Quinone reductase inhibitors b ...... hways and potentiate apoptosis
@ast
Quinone reductase inhibitors b ...... hways and potentiate apoptosis
@en
Quinone reductase inhibitors b ...... hways and potentiate apoptosis
@nl
type
label
Quinone reductase inhibitors b ...... hways and potentiate apoptosis
@ast
Quinone reductase inhibitors b ...... hways and potentiate apoptosis
@en
Quinone reductase inhibitors b ...... hways and potentiate apoptosis
@nl
prefLabel
Quinone reductase inhibitors b ...... hways and potentiate apoptosis
@ast
Quinone reductase inhibitors b ...... hways and potentiate apoptosis
@en
Quinone reductase inhibitors b ...... hways and potentiate apoptosis
@nl
P2093
P2860
P356
P1476
Quinone reductase inhibitors b ...... hways and potentiate apoptosis
@en
P2093
D Gustafson
D J Templeton
L A Parrott
S Vande Pol
P2860
P304
P356
10.1074/JBC.274.44.31150
P407
P577
1999-10-29T00:00:00Z