Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer
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Epigenetic perturbations in aging stem cellsCurrent understanding concerning intestinal stem cellsFrequent Somatic Mutation in Adult Intestinal Stem Cells Drives Neoplasia and Genetic Mosaicism during AgingAcceleration of leukocytes' epigenetic age as an early tumor and sex-specific marker of breast and colorectal cancer.Inhibition of NF-κB improves the stress resistance and myogenic differentiation of MDSPCs isolated from naturally aged miceIdentification of Aging-Associated Gene Expression Signatures That Precede Intestinal Tumorigenesis.Autologous hematopoietic stem cell transplantation in lymphoma patients is associated with a decrease in the double strand break repair capacity of peripheral blood lymphocytesUnderstanding the physiology of the ageing individual: computational modelling of changes in metabolism and endurance.Increased IL-6 secretion by aged human mesenchymal stromal cells disrupts hematopoietic stem and progenitor cells' homeostasis.Canine Adipose Derived Mesenchymal Stem Cells Transcriptome Composition Alterations: A Step towards Standardizing Therapeutic.Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regionsGenomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions.Epigenetic drift, epigenetic clocks and cancer risk.Metabolic regulation of stem cell function in tissue homeostasis and organismal ageing.Are microRNAs true sensors of ageing and cellular senescence?Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation.DNA-damage response in hematopoietic stem cells: an evolutionary trade-off between blood regeneration and leukemia suppression.Defective replication stress response inhibits lymphomagenesis and impairs lymphocyte reconstitution.Steroid Hormones and the Physiological Regulation of Tissue-Resident Stem Cells: Lessons from the Drosophila Ovary.Neurobiological mechanisms of stress resilience and implications for the aged population.Ubiquitin-Dependent Regulation of Stem Cell Biology.Ultra-sensitive Sequencing Identifies High Prevalence of Clonal Hematopoiesis-Associated Mutations throughout Adult Life.Cell-based immunotherapy with cytokine-induced killer (CIK) cells: From preparation and testing to clinical application.Hematopoietic Stem Cells Are the Major Source of Multilineage Hematopoiesis in Adult AnimalsIsolation and Characterization of Mesenchymal Stromal Cells from Human Umbilical Cord and Fetal Placenta.A Thymic Epithelial Stem Cell Pool Persists throughout Ontogeny and Is Modulated by TGF-β.Tissue-resident stem cell activity: a view from the adult Drosophila gastrointestinal tract.RNA Splicing Modulation Selectively Impairs Leukemia Stem Cell Maintenance in Secondary Human AMLPiwi Is Required to Limit Exhaustion of Aging Somatic Stem Cells.Oral primary care: an analysis of its impact on the incidence and mortality rates of oral cancer.Measuring mutation accumulation in single human adult stem cells by whole-genome sequencing of organoid cultures.Dietary Regulation of Adult Stem Cells.PARI Regulates Stalled Replication Fork Processing To Maintain Genome Stability upon Replication Stress in Mice.Therapeutic Potential and Cellular Mechanisms of Panax Notoginseng on Prevention of Aging and Cell Senescence-Associated Diseases.Clonality in context: hematopoietic clones in their marrow environment.Clonal Hematopoiesis and Evolution to Hematopoietic Malignancies.Leukaemia: Vitamin C regulates stem cells and cancer.Somatic mutagenesis in satellite cells associates with human skeletal muscle aging.Nucleotide Excision Repair: From Neurodegeneration to Cancer.Donor cell leukemia arising from preleukemic clones with a novel germline DDX41 mutation after allogenic hematopoietic stem cell transplantation.
P2860
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P2860
Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer
description
2015 nî lūn-bûn
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2015 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունիսին հրատարակված գիտական հոդված
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2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
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name
Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer
@ast
Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer
@en
Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer
@nl
type
label
Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer
@ast
Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer
@en
Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer
@nl
prefLabel
Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer
@ast
Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer
@en
Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer
@nl
P2860
P921
P3181
P1433
P1476
Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer
@en
P2093
Heinrich Jasper
Peter D Adams
P2860
P304
P3181
P356
10.1016/J.STEM.2015.05.002
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P5008
P577
2015-06-04T00:00:00Z