A broad phenotypic screen identifies novel phenotypes driven by a single mutant allele in Huntington's disease CAG knock-in mice.
about
HdhQ111 Mice Exhibit Tissue Specific Metabolite Profiles that Include Striatal Lipid AccumulationMotivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington's disease.High-resolution respirometry of fine-needle muscle biopsies in pre-manifest Huntington's disease expansion mutation carriers shows normal mitochondrial respiratory function.Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington's diseaseA selective inhibitor of histone deacetylase 3 prevents cognitive deficits and suppresses striatal CAG repeat expansions in Huntington's disease miceChromosome substitution strain assessment of a Huntington's disease modifier locusConditional Reduction of Adult Born Doublecortin-Positive Neurons Reversibly Impairs Selective Behaviors.Quantitative Electroencephalographic Analysis Provides an Early-Stage Indicator of Disease Onset and Progression in the zQ175 Knock-In Mouse Model of Huntington's Disease.Effects of Pin1 Loss in Hdh(Q111) Knock-in Mice.A Longitudinal Motor Characterisation of the HdhQ111 Mouse Model of Huntington's DiseaseGenetic modifiers of Huntington's disease.Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms.Methylene Blue Partially Rescues Heart Defects in a Drosophila Model of Huntington's Disease.Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss.Meis1: effects on motor phenotypes and the sensorimotor system in miceHigh resolution time-course mapping of early transcriptomic, molecular and cellular phenotypes in Huntington's disease CAG knock-in mice across multiple genetic backgrounds.Fgf9 (Y162C) Mutation Alters Information Processing and Social Memory in Mice.Progress in developing transgenic monkey model for Huntington's disease.HttQ111/+ Huntington's Disease Knock-in Mice Exhibit Brain Region-Specific Morphological Changes and Synaptic Dysfunction.
P2860
Q28386493-9C2EBC77-1DC6-442C-9E01-2CF80DFC1CB6Q30837903-D3F074ED-DDB2-46B4-8F48-2A739660FD78Q33562672-F61CFD5B-F6FB-4BFA-BBDA-27890018545AQ33614987-941951DA-9768-43EE-ADED-0206D798E04AQ33920945-79394156-B411-43E9-AEC6-7D3FE3C94165Q35214662-81CCF025-6582-4F58-BBB1-72300FB82E1CQ36272958-A7DFD32D-FC01-4FDB-8ED9-800A9E4BB71EQ36461072-2227F205-3F87-472F-B3CD-76BF16C8DFE1Q36854994-265E0D35-34AF-49F9-9E7C-668730251B07Q37089398-895120D1-CEFD-4587-8EF2-801AFBAD7206Q38243002-946F4161-BA52-412E-BF57-F83EBE060087Q39134355-C03455CB-15CC-4E77-9E88-8B444DE6ECEBQ40511148-DBBA537F-6B87-48E8-9889-C10509A376D7Q40999814-41468C65-E072-4583-827E-6AA18B04F81CQ41440563-683B8098-167D-428B-ACF3-74D0879942FAQ45301191-CFB447AF-8AC7-42BB-A182-8A96EB153253Q47787881-79BEFD67-4A48-410F-8CC6-289C5EFA118EQ47974512-C866C889-1515-4CDD-A847-A1AB7353DD0EQ52685690-309303AD-5535-4C07-8FF6-8163477F43D4
P2860
A broad phenotypic screen identifies novel phenotypes driven by a single mutant allele in Huntington's disease CAG knock-in mice.
description
2013 nî lūn-bûn
@nan
2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
A broad phenotypic screen iden ...... on's disease CAG knock-in mice
@nl
A broad phenotypic screen iden ...... n's disease CAG knock-in mice.
@ast
A broad phenotypic screen iden ...... n's disease CAG knock-in mice.
@en
type
label
A broad phenotypic screen iden ...... on's disease CAG knock-in mice
@nl
A broad phenotypic screen iden ...... n's disease CAG knock-in mice.
@ast
A broad phenotypic screen iden ...... n's disease CAG knock-in mice.
@en
prefLabel
A broad phenotypic screen iden ...... on's disease CAG knock-in mice
@nl
A broad phenotypic screen iden ...... n's disease CAG knock-in mice.
@ast
A broad phenotypic screen iden ...... n's disease CAG knock-in mice.
@en
P2093
P2860
P50
P3181
P1433
P1476
A broad phenotypic screen iden ...... n's disease CAG knock-in mice.
@en
P2093
Alexander Götz
Anja Schrewed
Birgit Rathkolb
Eckhard Wolf
Edith Lopez
Helmut Fuchs
Hiroko Wakimoto
Holger Schulz
Jolene Guide
Jonathan Seidman
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0080923
P407
P50
P577
2013-11-22T00:00:00Z