A dynamic model of interactions of Ca2+, calmodulin, and catalytic subunits of Ca2+/calmodulin-dependent protein kinase II
about
Calcium input frequency, duration and amplitude differentially modulate the relative activation of calcineurin and CaMKIIMechanisms of CaMKII action in long-term potentiationA Mechanism for Tunable Autoinhibition in the Structure of a Human Ca2+/Calmodulin- Dependent Kinase II HoloenzymeStructural analysis and stochastic modelling suggest a mechanism for calmodulin trapping by CaMKIITransfer functions for protein signal transduction: application to a model of striatal neural plasticityCaMKII activation and dynamics are independent of the holoenzyme structure: an infinite subunit holoenzyme approximationSKF83959, an agonist of phosphatidylinositol-linked D(1)-like receptors, promotes ERK1/2 activation and cell migration in cultured rat astrocytes.Reaction-diffusion in the NEURON simulator.Model reduction for stochastic CaMKII reaction kinetics in synapses by graph-constrained correlation dynamicsMolecular mechanism of activation-triggered subunit exchange in Ca(2+)/calmodulin-dependent protein kinase IIThe delicate bistability of CaMKIIA model for regulation by SynGAP-α1 of binding of synaptic proteins to PDZ-domain 'Slots' in the postsynaptic densityCombining modelling and experimental approaches to explain how calcium signatures are decoded by calmodulin-binding transcription activators (CAMTAs) to produce specific gene expression responses.Postsynaptic signal transduction models for long-term potentiation and depression.Cooperative binding mitigates the high-dose hook effect.A novel explanation for observed CaMKII dynamics in dendritic spines with added EGTA or BAPTA.Calcium messenger heterogeneity: a possible signal for spike timing-dependent plasticity.Competitive tuning: Competition's role in setting the frequency-dependence of Ca2+-dependent proteins.Biophysical attributes that affect CaMKII activation deduced with a novel spatial stochastic simulation approach.
P2860
Q21134074-8F3581B1-CC5E-49F0-82C4-34D2896D5849Q26998387-7A3F458A-4E97-4E50-BD67-76DFAE175B81Q27672798-A7D1B7C5-A538-4E17-8D70-7260D7B3FFABQ28478949-CF5DB462-1500-45A6-BE9D-D140457A879BQ28485989-720F964C-BE0B-4205-84F3-19DE718CFDAAQ34280253-F14271EE-EDA4-414C-A553-0DF949E4F965Q34490765-D4B3548A-4157-469B-85BA-8B56694D9CF0Q35057897-9B34F154-2339-4224-BD5A-E00BACD97730Q35667128-86D499CE-AAAE-48CC-98BA-AFCC317A7A22Q36879246-B26B10BC-3277-4F5E-A8DF-708B44D8B1FBQ37078290-FECC64AB-2FC3-48B9-A604-6090A19B9151Q37292998-CA2CA075-C183-4DDC-9AA5-6730F37C1FC5Q40194341-3541CAE6-C49A-41AE-B06B-8B51BE6EEB9FQ41331576-39CBFA4A-74D2-48FC-858F-97877539E7B2Q41396728-E03DB22F-7AE4-4914-A3EE-A8F56C46FAF2Q41403267-CED60C48-573A-40BB-A86F-818D68368805Q42576076-69A6FBC8-5D3B-457C-80D5-208CCAB2A0B4Q45787586-4E793437-A7B4-42DB-A66E-1C948D53434CQ48105788-C2E53ED1-24AE-4BA9-A231-D9F1C4793433
P2860
A dynamic model of interactions of Ca2+, calmodulin, and catalytic subunits of Ca2+/calmodulin-dependent protein kinase II
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A dynamic model of interaction ...... in-dependent protein kinase II
@ast
A dynamic model of interaction ...... in-dependent protein kinase II
@en
A dynamic model of interaction ...... in-dependent protein kinase II
@nl
type
label
A dynamic model of interaction ...... in-dependent protein kinase II
@ast
A dynamic model of interaction ...... in-dependent protein kinase II
@en
A dynamic model of interaction ...... in-dependent protein kinase II
@nl
prefLabel
A dynamic model of interaction ...... in-dependent protein kinase II
@ast
A dynamic model of interaction ...... in-dependent protein kinase II
@en
A dynamic model of interaction ...... in-dependent protein kinase II
@nl
P2093
P2860
P3181
P1476
A dynamic model of interaction ...... in-dependent protein kinase II
@en
P2093
Mary B Kennedy
Shirley Pepke
Stefan Mihalas
Tamara Kinzer-Ursem
P2860
P304
P3181
P356
10.1371/JOURNAL.PCBI.1000675
P407
P577
2010-02-12T00:00:00Z