KSHV reactivation from latency requires Pim-1 and Pim-3 kinases to inactivate the latency-associated nuclear antigen LANA - Test2 - elhamkhani - TriplyDB

KSHV reactivation from latency requires Pim-1 and Pim-3 kinases to inactivate the latency-associated nuclear antigen LANA

KSHV reactivation from latency requires Pim-1 and Pim-3 kinases to inactivate the latency-associated nuclear antigen LANA

http://www.wikidata.org/entity/Q28474913

about

PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers Kaposi's Sarcoma Herpesvirus Genome Persistence Activation of DNA Damage Response Induced by the Kaposi's Sarcoma-Associated Herpes Virus Cell Cycle Regulatory Functions of the KSHV Oncoprotein LANA Tricyclic Benzo[cd]azulenes selectively inhibit activities of Pim kinases and restrict growth of Epstein-Barr virus-transformed cells KSHV reactivation and novel implications of protein isomerization on lytic switch control The PIM kinases in hematological cancers Nucleophosmin phosphorylation by v-cyclin-CDK6 controls KSHV latency.Downregulation of IRF4 induces lytic reactivation of KSHV in primary effusion lymphoma cells CDK9 inhibitor FIT-039 prevents replication of multiple DNA viruses.Pathophysiological roles of Pim-3 kinase in pancreatic cancer development and progression.Viral latency and its regulation: lessons from the gamma-herpesviruses.Phosphorylation of the chromatin binding domain of KSHV LANA Altering the Anti-inflammatory Lipoxin Microenvironment: a New Insight into Kaposi's Sarcoma-Associated Herpesvirus Pathogenesis.KSHV LANA--the master regulator of KSHV latency.Mechanisms of Kaposi's Sarcoma-Associated Herpesvirus Latency and Reactivation Molecular biology of KSHV lytic reactivation.Cellular MicroRNA Let-7a Suppresses KSHV Replication through Targeting MAP4K4 Signaling Pathways.Post-Translational Modifications of Kaposi's Sarcoma-Associated Herpesvirus Regulatory Proteins - SUMO and KSHV Protein arginine methyltransferase 1-directed methylation of Kaposi sarcoma-associated herpesvirus latency-associated nuclear antigen.Oncogenic Herpesvirus Utilizes Stress-Induced Cell Cycle Checkpoints for Efficient Lytic Replication Kaposi's sarcoma-associated herpesvirus inhibits expression and function of endothelial cell major histocompatibility complex class II via suppressor of cytokine signaling 3 Professional antigen presenting cells in human herpesvirus 8 infection.The inflammatory kinase MAP4K4 promotes reactivation of Kaposi's sarcoma herpesvirus and enhances the invasiveness of infected endothelial cells The latency-associated nuclear antigen, a multifunctional protein central to Kaposi's sarcoma-associated herpesvirus latency.Phosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells.The PIM family of serine/threonine kinases in cancer.Epigenetic regulation of EBV and KSHV latency The chromatin landscape of Kaposi's sarcoma-associated herpesvirus.The role of Kaposi sarcoma-associated herpesvirus in the pathogenesis of Kaposi sarcoma.PIM kinase (and Akt) biology and signaling in tumors.The Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus Inhibits Expression of SUMO/Sentrin-Specific Peptidase 6 To Facilitate Establishment of Latency.The K1 Protein of Kaposi's Sarcoma-Associated Herpesvirus Augments Viral Lytic Replication.Full-Length Isoforms of Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Accumulate in the Cytoplasm of Cells Undergoing the Lytic Cycle of Replication.The Kaposi's sarcoma-associated herpesvirus (KSHV) non-structural membrane protein K15 is required for viral lytic replication and may represent a therapeutic target.Tousled-like kinases modulate reactivation of gammaherpesviruses from latency.Kaposi's sarcoma herpesvirus lytic replication compromises apoptotic response to p53 reactivation in virus-induced lymphomas.The regulatory role of protein phosphorylation in human gammaherpesvirus associated cancers.Nucleolar stress enhances lytic reactivation of the Kaposi's sarcoma-associated herpesvirus.

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KSHV reactivation from latency requires Pim-1 and Pim-3 kinases to inactivate the latency-associated nuclear antigen LANA

http://www.wikidata.org/entity/Q28474913

description

2009 nî lūn-bûn

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2009 թուականի Մարտին հրատարակուած գիտական յօդուած

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2009 թվականի մարտին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

KSHV reactivation from latency ...... ssociated nuclear antigen LANA

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KSHV reactivation from latency ...... ssociated nuclear antigen LANA

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KSHV reactivation from latency ...... ssociated nuclear antigen LANA

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type

label

KSHV reactivation from latency ...... ssociated nuclear antigen LANA

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KSHV reactivation from latency ...... ssociated nuclear antigen LANA

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KSHV reactivation from latency ...... ssociated nuclear antigen LANA

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prefLabel

KSHV reactivation from latency ...... ssociated nuclear antigen LANA

@ast

KSHV reactivation from latency ...... ssociated nuclear antigen LANA

@en

KSHV reactivation from latency ...... ssociated nuclear antigen LANA

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JOURNAL.PPAT.1000324

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KSHV reactivation from latency ...... ssociated nuclear antigen LANA

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Anne Lehtonen

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Eeva-Marja Rainio

http://www.w3.org/2001/XMLSchema#string

Fang Cheng

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Jussi Taipale

http://www.w3.org/2001/XMLSchema#string

Magdalena Weidner-Glunde

http://www.w3.org/2001/XMLSchema#string

Markku Varjosalo

http://www.w3.org/2001/XMLSchema#string

Päivi J Koskinen

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Päivi M Ojala

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Thomas F Schulz

http://www.w3.org/2001/XMLSchema#string

P2860

Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling

The human protooncogene product p33pim is expressed during fetal hematopoiesis and in diverse leukemias

Identification of the gene encoding the major latency-associated nuclear antigen of the Kaposi's sarcoma-associated herpesvirus

Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors

The 222- to 234-kilodalton latent nuclear protein (LNA) of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) is encoded by orf73 and is a component of the latency-associated nuclear antigen

Pim kinases are upregulated during Epstein-Barr virus infection and enhance EBNA2 activity

The serine/threonine kinase Pim-1

Delineation of prognostic biomarkers in prostate cancer

Structure and substrate specificity of the Pim-1 kinase.

Systematic identification of cellular signals reactivating Kaposi sarcoma-associated herpesvirus.

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e1000324

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10.1371/JOURNAL.PPAT.1000324

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