Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling
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FGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase-FGFR4 complexInterlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MSPhospho-tyrosine dependent protein-protein interaction networkThe hedgehog pathway in triple-negative breast cancerCooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapySynthetic lethal screens as a means to understand and treat MYC-driven cancersStructures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate RecognitionEngagement of DYRK2 in proper control for cell divisionIntegrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapyKSHV reactivation from latency requires Pim-1 and Pim-3 kinases to inactivate the latency-associated nuclear antigen LANAMouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathwayTubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signalingDYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistanceThe primary cilium: a signalling centre during vertebrate developmentEphA2 cleavage by MT1-MMP triggers single cancer cell invasion via homotypic cell repulsion.Making sense of cancer genomic data.Mechanism and evolution of cytosolic Hedgehog signal transductionYeast-based assay identifies novel Shh/Gli target genes in vertebrate developmentDeep evolutionary conservation of an intramolecular protein kinase activation mechanism.Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway.Human kinome analysis reveals novel kinases contributing to virus infection and retinoic-acid inducible gene I-induced type I and type III IFN gene expression.Hedgehog activates fused through phosphorylation to elicit a full spectrum of pathway responsesClinical implications of hedgehog signaling pathway inhibitorsThe Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis.Post-Translational Modifications of Kaposi's Sarcoma-Associated Herpesvirus Regulatory Proteins - SUMO and KSHVProtein arginine methyltransferase 1-directed methylation of Kaposi sarcoma-associated herpesvirus latency-associated nuclear antigen.DYRK2 Negatively Regulates Type I Interferon Induction by Promoting TBK1 Degradation via Ser527 Phosphorylation.Oncogenic Herpesvirus Utilizes Stress-Induced Cell Cycle Checkpoints for Efficient Lytic ReplicationRegulation of Hedgehog signaling by ubiquitination.Sequential phosphorylation of smoothened transduces graded hedgehog signaling.Expression analysis of multiple myeloma CD138 negative progenitor cells using single molecule microarray readout.Receptor tyrosine kinase EphA7 is required for interneuron connectivity at specific subcellular compartments of granule cells.Isotope-coded ATP probe for quantitative affinity profiling of ATP-binding proteins.Hedgehog-Gli signaling pathway inhibitors as anticancer agents.Phosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells.Acute myeloid leukemia - strategies and challenges for targeting oncogenic Hedgehog/GLI signalingProtein kinase inhibitor SU6668 attenuates positive regulation of Gli proteins in cancer and multipotent progenitor cells.Activation of the hedgehog-signaling pathway in human cancer and the clinical implications.Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signalsHedgehog signaling in skin cancers
P2860
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P2860
Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Application of active and kina ...... regulating hedgehog signaling
@ast
Application of active and kina ...... regulating hedgehog signaling
@en
Application of active and kina ...... regulating hedgehog signaling
@en-gb
Application of active and kina ...... regulating hedgehog signaling
@nl
type
label
Application of active and kina ...... regulating hedgehog signaling
@ast
Application of active and kina ...... regulating hedgehog signaling
@en
Application of active and kina ...... regulating hedgehog signaling
@en-gb
Application of active and kina ...... regulating hedgehog signaling
@nl
prefLabel
Application of active and kina ...... regulating hedgehog signaling
@ast
Application of active and kina ...... regulating hedgehog signaling
@en
Application of active and kina ...... regulating hedgehog signaling
@en-gb
Application of active and kina ...... regulating hedgehog signaling
@nl
P2093
P50
P921
P3181
P1433
P1476
Application of active and kina ...... regulating hedgehog signaling
@en
P2093
Fang Cheng
Heidi Syvänen
Hendrik G Stunnenberg
Jussi Taipale
Sami Kilpinen
Teemu Kivioja
Zairen Sun
P304
P3181
P356
10.1016/J.CELL.2008.02.047
P407
P577
2008-05-01T00:00:00Z