about
Epistatic adaptive evolution of human color visionStability-mediated epistasis constrains the evolution of an influenza proteinPredictability of evolutionary trajectories in fitness landscapesFrom systems to structure: bridging networks and mechanismEvolution of mitochondrial power in vertebrate metazoansConnecting Active-Site Loop Conformations and Catalysis in Triosephosphate Isomerase: Insights from a Rare Variation at Residue 96 in the Plasmodial EnzymeCan the experimental evolution programme help us elucidate the genetic basis of adaptation in nature?Epistatic interaction maps relative to multiple metabolic phenotypesStrong Selection Significantly Increases Epistatic Interactions in the Long-Term Evolution of a ProteinReverse evolution leads to genotypic incompatibility despite functional and active site convergenceAdaptive evolutionary paths from UV reception to sensing violet light by epistatic interactionsThe Valley-of-Death: reciprocal sign epistasis constrains adaptive trajectories in a constant, nutrient limiting environmentContingency and entrenchment in protein evolution under purifying selectionCancer in light of experimental evolutionQuantification of the transferability of a designed protein specificity switch reveals extensive epistasis in molecular recognitionThe Patterns of Coevolution in Clade B HIV Envelope's N-Glycosylation SitesEstimating the rate of irreversibility in protein evolution.Residue mutations and their impact on protein structure and function: detecting beneficial and pathogenic changes.Identifying the elusive link between amino acid sequence and charge selectivity in pentameric ligand-gated ion channels.Inferring fitness landscapes by regression produces biased estimates of epistasis.Causes of molecular convergence and parallelism in protein evolution.Transcriptional robustness and protein interactions are associated in yeast.Reciprocal sign epistasis between frequently experimentally evolved adaptive mutations causes a rugged fitness landscape.An experimentally determined evolutionary model dramatically improves phylogenetic fit.Plastids, genomes, and the probability of gene transfer.An experimentally informed evolutionary model improves phylogenetic fit to divergent lactamase homologsAdaptive evolution: evaluating empirical support for theoretical predictions.Colon cancer associated genes exhibit signatures of positive selection at functionally significant positionsEvolutionary biochemistry: revealing the historical and physical causes of protein properties.Coevolution within and between regulatory loci can preserve promoter function despite evolutionary rate acceleration.Thermodynamic system drift in protein evolution.Replaying the tape of life: quantification of the predictability of evolution.Bacilli glutamate dehydrogenases diverged via coevolution of transcription and enzyme regulation.The environment affects epistatic interactions to alter the topology of an empirical fitness landscapeA systematic survey of an intragenic epistatic landscape.Environmental dependence of genetic constraint.Latent effects of Hsp90 mutants revealed at reduced expression levels.Mechanisms of protein sequence divergence and incompatibility.Slow protein evolutionary rates are dictated by surface-core association.Weighing the evidence for adaptation at the molecular level
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Pervasive cryptic epistasis in molecular evolution
@ast
Pervasive cryptic epistasis in molecular evolution
@en
Pervasive cryptic epistasis in molecular evolution
@nl
type
label
Pervasive cryptic epistasis in molecular evolution
@ast
Pervasive cryptic epistasis in molecular evolution
@en
Pervasive cryptic epistasis in molecular evolution
@nl
prefLabel
Pervasive cryptic epistasis in molecular evolution
@ast
Pervasive cryptic epistasis in molecular evolution
@en
Pervasive cryptic epistasis in molecular evolution
@nl
P2093
P2860
P3181
P1433
P1476
Pervasive cryptic epistasis in molecular evolution
@en
P2093
Antony M Dean
G Brian Golding
Mark Lunzer
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1001162
P407
P577
2010-10-21T00:00:00Z