Chemical chaperones improve protein secretion and rescue mutant factor VIII in mice with hemophilia A
about
Gene therapy for hemophiliaSynergistic Inhibition of Protein Fibrillation by Proline and Sorbitol: Biophysical InvestigationsThe F309S mutation increases factor VIII secretion in human cell lineSLC30A10 is a cell surface-localized manganese efflux transporter, and parkinsonism-causing mutations block its intracellular trafficking and efflux activityA thermolabile aldolase A mutant causes fever-induced recurrent rhabdomyolysis without hemolytic anemia.The impact of germline mutations on targeted therapy.Innovative strategies to treat protein misfolding in inborn errors of metabolism: pharmacological chaperones and proteostasis regulators.Use of a protein engineering strategy to overcome limitations in the production of "Difficult to Express" recombinant proteins.Integrated cell and process engineering for improved transient production of a "difficult-to-express" fusion protein by CHO cells.
P2860
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P2860
Chemical chaperones improve protein secretion and rescue mutant factor VIII in mice with hemophilia A
description
2012 nî lūn-bûn
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2012 թուականին հրատարակուած գիտական յօդուած
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2012 թվականին հրատարակված գիտական հոդված
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年论文
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name
Chemical chaperones improve pr ...... VIII in mice with hemophilia A
@ast
Chemical chaperones improve pr ...... VIII in mice with hemophilia A
@en
Chemical chaperones improve pr ...... VIII in mice with hemophilia A
@nl
type
label
Chemical chaperones improve pr ...... VIII in mice with hemophilia A
@ast
Chemical chaperones improve pr ...... VIII in mice with hemophilia A
@en
Chemical chaperones improve pr ...... VIII in mice with hemophilia A
@nl
prefLabel
Chemical chaperones improve pr ...... VIII in mice with hemophilia A
@ast
Chemical chaperones improve pr ...... VIII in mice with hemophilia A
@en
Chemical chaperones improve pr ...... VIII in mice with hemophilia A
@nl
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Chemical chaperones improve pr ...... VIII in mice with hemophilia A
@en
P2093
Christopher Ungerer
Daniela Abriss
Erhard Seifried
Patricia Quade-Lyssy
Peter Milanov
Stefanie D Roth
Torsten Tonn
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P304
P3181
P356
10.1371/JOURNAL.PONE.0044505
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2012-09-04T00:00:00Z