about
The FGF21-adiponectin axis in controlling energy and vascular homeostasisFibroblast Growth Factor Signaling in Metabolic RegulationUnlock the Thermogenic Potential of Adipose Tissue: Pharmacological Modulation and Implications for Treatment of Diabetes and ObesityInventing new medicines: The FGF21 storyRational design of a fibroblast growth factor 21-based clinical candidate, LY2405319Hepatic Fgf21 Expression Is Repressed after Simvastatin Treatment in Miceβ-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue.Metabolic role of fibroblast growth factor 21 in liver, adipose and nervous system tissues.Reduced adiposity attenuates FGF21 mediated metabolic improvements in the Siberian hamster.Cellular mechanisms by which FGF21 improves insulin sensitivity in male miceFGF21 can be mimicked in vitro and in vivo by a novel anti-FGFR1c/β-Klotho bispecific protein.Tissue-specific actions of the metabolic hormones FGF15/19 and FGF21.LY2405319, an Engineered FGF21 Variant, Improves the Metabolic Status of Diabetic MonkeysAssociation between Serum Atypical Fibroblast Growth Factors 21 and 19 and Pediatric Nonalcoholic Fatty Liver Disease.Fibroblast growth factor 21 improves insulin sensitivity and synergizes with insulin in human adipose stem cell-derived (hASC) adipocytes.A preliminary candidate approach identifies the combination of chemerin, fetuin-A, and fibroblast growth factors 19 and 21 as a potential biomarker panel of successful aging.Adipose tissue plasticity from WAT to BAT and in between.Fibroblast growth factor 21 prevents atherosclerosis by suppression of hepatic sterol regulatory element-binding protein-2 and induction of adiponectin in mice.Central Fibroblast Growth Factor 21 Browns White Fat via Sympathetic Action in Male Mice.FGF21 Mediates Endocrine Control of Simple Sugar Intake and Sweet Taste Preference by the LiverMetabolic fibroblast growth factors (FGFs): Mediators of energy homeostasis.An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice.The Nuclear Receptor Rev-erbα Regulates Adipose Tissue-specific FGF21 Signaling.Endocrine protection of ischemic myocardium by FGF21 from the liver and adipose tissue.Expression profile and overexpression outcome indicate a role for βKlotho in skeletal muscle fibro/adipogenesis.Interplay between FGF21 and insulin action in the liver regulates metabolism.Therapeutic potential of the endocrine fibroblast growth factors FGF19, FGF21 and FGF23.FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in whole-body glucose homeostasis.The emerging role of fibroblast growth factor 21 in diabetic nephropathy.Cardiac actions of fibroblast growth factor 23.Fibroblast growth factor 21 night watch: advances and uncertainties in the field.Fibroblast Growth Factor 21-Null Mice Do Not Exhibit an Impaired Response to Fasting.Fibroblast growth factor 21 improves hepatic insulin sensitivity by inhibiting mammalian target of rapamycin complex 1 in mice.Novel sandwich immunoassays for the measurement of total and active FGF21.Fibroblast growth factor 21 is not required for the antidiabetic actions of the thiazoladinediones.Sugar-sweetened beverage intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta-analysis.Antibody-Mediated Targeting of the FGFR1c Isoform Increases Glucose Uptake in White and Brown Adipose Tissue in Male Mice.FGF21 Is an Insulin-Dependent Postprandial Hormone in Adult Humans.Peripherally derived FGF21 promotes remyelination in the central nervous system.FGF21, a liver hormone that inhibits alcohol intake in mice, increases in human circulation after acute alcohol ingestion and sustained binge drinking at Oktoberfest.
P2860
Q26753369-0E2D4ABD-EA4A-4691-8D29-00139B9A6AB8Q26772751-5285681C-EF51-483A-8925-0FCD1B9466E9Q26774736-3B102A18-6776-4A70-8B16-95431C608CBFQ26823319-75CBF3DF-8F98-438D-B7A3-E27FD94BCB3AQ28487909-BC6D934C-F6E8-4625-A845-4F471DB7AF1BQ28553822-7506BBA2-10E3-4F3D-A40B-3686E3646E7BQ33578966-7F3BCC75-795A-4329-B03E-6147487C2A98Q33685319-DA4FE427-1795-440D-B4AC-324810B67F4AQ33835303-E5E4BC2F-5E02-49E1-98AB-86405B3F12A9Q34350772-B6B3F706-E64E-4609-AD56-1A2F1BC37939Q34695496-8FBC947A-658E-4BFC-BC7F-1E6835FCD2DBQ34778879-79C35AA3-3844-4207-99BE-6ED87C3FA2BEQ34792753-60F98A25-C7F5-4DF1-AE8D-C6415C6A5E96Q34806589-A934F807-ED75-4437-AE7F-91268B080AE2Q35387801-B685CB7C-CB94-41EA-B452-543D33D91798Q35537498-87A2AF75-3BB3-4B33-B87C-B63AD3062561Q35619414-D80AD9FE-19EA-42F7-BB0B-1B912E88FBD8Q35648897-8D0A7864-65BC-413D-9847-3BC942950721Q35763646-984C643C-5E81-40EC-BE60-2D8BA3F2AF44Q36588765-25FCB5CE-F327-4119-A6AB-D0C50A0CE82EQ36746670-E2ECD8A5-F912-4B01-ADDA-7EC3B81B1E82Q36886578-1C8EC754-0420-4D8A-990E-FD9546119EA9Q36898306-E93AAA4A-EF01-45F5-8CAC-5B751B356906Q37199307-5E81B483-1E8C-49B9-AE8A-D032647E0B33Q37351645-32AE4508-E9B1-43B1-93D2-1F4B69E0A39BQ37524205-B9025639-3D19-49AD-B37A-59CDF57AA376Q38633258-EAD695E0-5040-4F7E-90A4-42F385DDDA35Q38744561-28F48C66-0D20-468F-A14E-F0DB7712B69AQ38750211-661D2F10-797E-4A16-A2A0-28B6C6B2964FQ38977291-63E7AD13-7E1C-4BFD-997D-FB5924D85FAAQ39017842-9B263CA3-2B10-47AE-A13A-E36936651D2FQ39572533-A76E932A-91E5-4FF1-AE52-C6AFF7596529Q40880973-714E0A0C-85A7-4427-BED1-B9D837E39E30Q41656537-9F174A07-D545-4388-9653-7A7933ACD321Q42619250-A0700450-2D4D-4DBC-AC14-15EF177DA43BQ45071780-95478E7C-A8EB-4A25-975A-381525FEAE32Q47761014-2134CE4B-A7AF-4501-B311-B00D28B4446CQ47761142-76FA6671-0FB8-40A4-BF25-3AE6E4C11AF6Q47927815-5CCF1209-A389-4DA9-BF86-EE62A743347AQ53416059-1AFE6632-8CEE-4B66-BF56-31BE05644AAD
P2860
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
FGF21 requires βklotho to act in vivo
@ast
FGF21 requires βklotho to act in vivo
@en
FGF21 requires βklotho to act in vivo
@nl
type
label
FGF21 requires βklotho to act in vivo
@ast
FGF21 requires βklotho to act in vivo
@en
FGF21 requires βklotho to act in vivo
@nl
prefLabel
FGF21 requires βklotho to act in vivo
@ast
FGF21 requires βklotho to act in vivo
@en
FGF21 requires βklotho to act in vivo
@nl
P2093
P2860
P3181
P1433
P1476
FGF21 requires βklotho to act in vivo
@en
P2093
Alexei Kharitonenkov
Andrew C Adams
Christine C Cheng
Tamer Coskun
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0049977
P407
P577
2012-01-01T00:00:00Z