Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
about
A role for Alström syndrome protein, alms1, in kidney ciliogenesis and cellular quiescenceA method for measuring electrical signals in a primary ciliumTrafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulationPolycystin-1 and polycystin-2 regulate the cell cycle through the helix-loop-helix inhibitor Id2Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1Bardet-Biedl syndrome proteins 1 and 3 regulate the ciliary trafficking of polycystic kidney disease 1 proteinA polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexesUromodulin is expressed in renal primary cilia and UMOD mutations result in decreased ciliary uromodulin expressionIndividuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathyPericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assemblyThe human polycystin-2 protein represents an integral membrane protein with six membrane-spanning domains and intracellular N- and C-terminiPKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cellsLRRC50, a conserved ciliary protein implicated in polycystic kidney diseaseCiliary polycystin-2 is a mechanosensitive calcium channel involved in nitric oxide signaling cascadesInteraction between PKD1L3 and PKD2L1 through their transmembrane domains is required for localization of PKD2L1 at taste pores in taste cells of circumvallate and foliate papillaeRab10 associates with primary cilia and the exocyst complex in renal epithelial cells.Ciliary and centrosomal defects associated with mutation and depletion of the Meckel syndrome genes MKS1 and MKS3PKD2 interacts and co-localizes with mDia1 to mitotic spindles of dividing cells: role of mDia1 IN PKD2 localization to mitotic spindlesNephronophthisisClinical and genetic epidemiology of Bardet-Biedl syndrome in Newfoundland: a 22-year prospective, population-based, cohort studyDisruption of Mks1 localization to the mother centriole causes cilia defects and developmental malformations in Meckel-Gruber syndromeThe primary cilium as a cellular signaling center: lessons from diseaseTRPC6 in glomerular health and disease: what we know and what we believeThe cells and logic for mammalian sour taste detectionNovel and de novo PKD1 mutations identified by multiple restriction fragment-single strand conformation polymorphism (MRF-SSCP)Role of calcium in polycystic kidney disease: From signaling to pathologyThe functions of TRPP2 in the vascular systemThe Role of G-Protein-Coupled Receptor Proteolysis Site Cleavage of Polycystin-1 in Renal Physiology and Polycystic Kidney DiseaseRole of the Polycystins in Cell Migration, Polarity, and Tissue MorphogenesisGenetics and biology of primary ciliary dyskinesiaVascular complications in autosomal dominant polycystic kidney diseaseA polycystin-centric view of cyst formation and disease: the polycystins revisitedMating behavior, male sensory cilia, and polycystins in Caenorhabditis elegansPolycystin-1: a master regulator of intersecting cystic pathwaysCilia in vertebrate development and diseaseMicroRNAs in the pathogenesis of cystic kidney diseaseRenal urinary shear stress: a novel actor in nephropathiesSensory functions of motile cilia and implication for bronchiectasisPathophysiology of childhood polycystic kidney diseases: new insights into disease-specific therapyHow do cilia organize signalling cascades?
P2860
0daa3d93eec8327bc36275051ceb7f5b90fe0d302923e57d87526865bf1baaa1f7267bc706c7f26b2edbafe0a0db43bfbe91b48ae032c8fa9916407b486de1abd4832e567bdf2fc7cbedc55cdd62dbee4c79c791f7b733f62633047dde84fcffdb17f98768df80f1cabf444e3c88dc45802ba4770e7bc600702eeabc41bc50ba4c0222f4391c86b2000a25a791acfbc5ce118bc0eaddb46acbf3a9fc306c1db79ed26cab542453115cc75889b5da222dec7c3568bc55237109237349ccad1c8490b17d61dc3925be
P248
Q21092494-B13254EF-B820-47E0-82A9-7076721391F1Q22001112-61AC5854-A6D7-4101-BEA2-8DF4DC44174AQ24293752-9538D0A1-2C01-4170-97AB-3BD218F5A703Q24297056-6281FDE3-EEAA-47DF-8D53-3D47EAA39DCBQ24299323-E38501AC-F60D-45E7-943E-1126491E7463Q24299480-670E0B27-8605-4F8B-80D4-3B37261AA472Q24300157-5BF726C1-5D69-4A29-9EC8-CF5DADC78BE9Q24300384-4C35C430-5961-4C33-A317-999693F0EB1DQ24300810-F3824E86-6793-450D-AE59-F348DC8744B0Q24302124-74A00E2B-3019-4653-82A5-8EA7E9ADAB20Q24305249-D72607B8-12C6-4197-BB1D-9D568A8D6C72Q24311878-ACC1FF50-20F7-4766-AD87-0BDD6A35994EQ24316336-D0055B7C-779F-4D6D-80BA-7ACB69B41007Q24318379-1C5366DD-3841-4EB2-91DC-0BF7E40BE853Q24318877-7F9F10D1-9D1D-4025-B36F-6368E2783BBFQ24336100-44598436-6304-47B3-A361-992BB1C52CAEQ24337720-0E02705F-0FA1-4333-8B82-F7B7662C09ADQ24338591-B0AF88D2-12D1-4ED6-B968-05920B6AF325Q24601139-D1D8FB60-A5A5-4BFC-BDD9-A5985F8B9C0CQ24622509-59E14F23-DBBB-4AA9-A9A7-25695E690850Q24622660-CE649566-E082-4A6C-A1A1-9A52D50682DAQ24632942-D1A82226-D849-4A7E-BCE6-DFBCB596DBF6Q24652809-CAE6CB96-9AE8-415C-8750-1FD8A4728298Q24675916-D6C6C1E6-06D3-4575-B045-F691FCB4DF5CQ24799068-D47A8B62-9D1D-48F3-9941-52EA70CF37D6Q26770740-AA002CF0-4A44-4C63-BB76-B46321A19E38Q26771361-E6C4E231-69F8-4683-8900-D20D7E1D6FA6Q26775090-D751D61E-CA54-4852-8BB1-F0A1D9ACAD49Q26777057-1325B97B-7075-4676-BD5D-864DF53BAF3BQ26782119-0C24C6C5-AA86-4D35-832C-3A5E8137AD09Q26799638-143D3F3F-AB82-4C94-A4DE-483D9E289A5BQ26800974-21215A4D-452D-4B80-AC29-D16A8F84F5CFQ26823989-76405DB8-9D2B-405D-B47A-B725FFB56EEFQ26826955-752E64B6-AD1C-428E-A214-F4F5830787C6Q26829114-83B77A22-87AD-4A83-9490-7E196C305FFDQ26852641-96154113-45F7-4C43-83CC-F4A01FCE0F16Q26865487-10064751-8A1E-4110-9B06-20217D2F3075Q26992107-42A7B723-80E1-4194-86A1-8DF6B9EB7E80Q27000075-D140C1D3-B33C-4E1B-8A6A-1B7E78FBE96BQ27005693-0377508A-807F-4359-A4C9-EC862AE5761D
P2860
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
name
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
@ast
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
@en
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
@nl
type
label
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
@ast
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
@en
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
@nl
prefLabel
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
@ast
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
@en
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
@nl
P2093
P921
P3181
P356
P1433
P1476
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
@en
P2093
Andrew E. H. Elia
Edward M. Brown
Eric Williams
Francis J. Alenghat
Peter Vassilev
Stephen J. Quinn
Surya M. Nauli
Xiaogang Li
P2888
P304
P3181
P356
10.1038/NG1076
P407
P577
2003-02-01T00:00:00Z