Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
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Altered hematopoiesis in mice lacking DNA polymerase mu is due to inefficient double-strand break repairA mouse model of ATR-Seckel shows embryonic replicative stress and accelerated agingThe role of glutathione S-transferase P in signaling pathways and S-glutathionylation in cancerThe DNA-damage response in human biology and diseaseThe telomere syndromesOxidative stress, mitochondrial dysfunction, and agingLymphocyte-specific compensation for XLF/cernunnos end-joining functions in V(D)J recombinationTwo faces of p53: aging and tumor suppressionAging of hematopoietic stem cells: DNA damage and mutations?DNA Damage Response in Hematopoietic Stem Cell AgeingEnergy Metabolism Plays a Critical Role in Stem Cell Maintenance and DifferentiationGenetic and Epigenetic Mechanisms That Maintain Hematopoietic Stem Cell FunctionEpigenetic Control of Haematopoietic Stem Cell Aging and Its Clinical ImplicationsIonizing Particle Radiation as a Modulator of Endogenous Bone Marrow Cell Reprogramming: Implications for Hematological CancersChanges in Regenerative Capacity through LifespanMolecular mechanisms controlling asymmetric and symmetric self-renewal of cancer stem cellsFine-tuning the ubiquitin code at DNA double-strand breaks: deubiquitinating enzymes at workKlotho, stem cells, and agingOxidative stress, bone marrow failure, and genome instability in hematopoietic stem cellsChanges in primary lymphoid organs with agingLeukemia and benzeneSirtuins in hematological aging and malignancyT cell ageing: effects of age on development, survival & functionEpigenetic regulation of hematopoietic stem cell agingTranscriptome analysis reveals strain-specific and conserved stemness genes in Schmidtea mediterraneaTopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive HematopoiesisSelf-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansionLifespan extension by preserving proliferative homeostasis in DrosophilaAdult stem cell and mesenchymal progenitor theories of aging.Balancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?Inflamm-Aging of Hematopoiesis, Hematopoietic Stem Cells, and the Bone Marrow MicroenvironmentEvolved Cellular Mechanisms to Respond to Genotoxic Insults: Implications for Radiation-Induced Hematologic MalignanciesThe hallmarks of agingRestoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscleTif1γ regulates the TGF-β1 receptor and promotes physiological aging of hematopoietic stem cellsLoss of a single allele for Ku80 leads to progenitor dysfunction and accelerated aging in skeletal muscleLinking functional decline of telomeres, mitochondria and stem cells during ageingERCC1-XPF endonuclease facilitates DNA double-strand break repairThe role of telomeres and telomerase in stem cell agingAging-Induced Stem Cell Mutations as Drivers for Disease and Cancer
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P2860
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
description
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 2007
@ast
scientific journal article
@en
vedecký článok (publikovaný 2007/06/07)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/06/07)
@nl
наукова стаття, опублікована в червні 2007
@uk
مقالة علمية (نشرت في 7-6-2007)
@ar
name
Deficiencies in DNA damage rep ...... atopoietic stem cells with age
@ast
Deficiencies in DNA damage rep ...... atopoietic stem cells with age
@en
Deficiencies in DNA damage rep ...... atopoietic stem cells with age
@nl
type
label
Deficiencies in DNA damage rep ...... atopoietic stem cells with age
@ast
Deficiencies in DNA damage rep ...... atopoietic stem cells with age
@en
Deficiencies in DNA damage rep ...... atopoietic stem cells with age
@nl
prefLabel
Deficiencies in DNA damage rep ...... atopoietic stem cells with age
@ast
Deficiencies in DNA damage rep ...... atopoietic stem cells with age
@en
Deficiencies in DNA damage rep ...... atopoietic stem cells with age
@nl
P2093
P3181
P356
P1433
P1476
Deficiencies in DNA damage rep ...... atopoietic stem cells with age
@en
P2093
Andre Nussenzweig
Derrick J Rossi
Irving L Weissman
Jan Hoeijmakers
P2888
P304
P3181
P356
10.1038/NATURE05862
P407
P577
2007-06-01T00:00:00Z
P6179
1004325946