Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia
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Evc2 is a positive modulator of Hedgehog signalling that interacts with Evc at the cilia membrane and is also found in the nucleusNephronophthisisCiliary abnormalities due to defects in the retrograde transport protein DYNC2H1 in short-rib polydactyly syndromeThe primary cilium as a dual sensor of mechanochemical signals in chondrocytesCilia/Ift protein and motor -related bone diseases and mouse modelsAxonemal positioning and orientation in three-dimensional space for primary cilia: what is known, what is assumed, and what needs clarificationDecoding the phosphorylation code in Hedgehog signal transductionDeletion in the EVC2 gene causes chondrodysplastic dwarfism in Tyrolean Grey cattleThe nonmotile ciliopathies.An Ift80 mouse model of short rib polydactyly syndromes shows defects in hedgehog signalling without loss or malformation of ciliaThe intraflagellar transport protein IFT80 is required for cilia formation and osteogenesisMolecular development of fibular reduction in birds and its evolution from dinosaursFunctional significance of SRJ domain mutations in CITED2The primary cilium: a signalling centre during vertebrate developmentOrthopaedic manifestations of chondroectodermal dysplasia: the Ellis-van Creveld syndrome.EFCAB7 and IQCE regulate hedgehog signaling by tethering the EVC-EVC2 complex to the base of primary cilia.Variations of CITED2 are associated with congenital heart disease (CHD) in Chinese population.Murine Joubert syndrome reveals Hedgehog signaling defects as a potential therapeutic target for nephronophthisisAnalysis of hedgehog signaling in mouse intraflagellar transport mutantsCiliopathies: an expanding disease spectrum.Low-frequency intermediate penetrance variants in the ROCK1 gene predispose to Tetralogy of FallotCilia involvement in patterning and maintenance of the skeletonMIM and cortactin antagonism regulates ciliogenesis and hedgehog signaling.The emerging face of primary cilia.Function and regulation of primary cilia and intraflagellar transport proteins in the skeletonThe ciliopathy gene Rpgrip1l is essential for hair follicle development.Specific variants in WDR35 cause a distinctive form of Ellis-van Creveld syndrome by disrupting the recruitment of the EvC complex and SMO into the cilium.Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice.Smoothened transduces Hedgehog signal by forming a complex with Evc/Evc2.From the transcription of genes involved in ectodermal dysplasias to the understanding of associated dental anomalies.Generation of Evc2/Limbin global and conditional KO mice and its roles during mineralized tissue formation.A Smoothened-Evc2 complex transduces the Hedgehog signal at primary cilia.A review of hedgehog signaling in cranial bone developmentThe primary cilia, a 'Rab-id' transit system for hedgehog signaling.The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and menThe primary cilium at the crossroads of mammalian hedgehog signalingAnalysis of Ellis van Creveld syndrome gene products: implications for cardiovascular development and diseaseThe primary cilium as a Hedgehog signal transduction machine.Cartilage cell clusters.Ellis-van Creveld syndrome and congenital heart defects: presentation of an additional 32 cases.
P2860
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P2860
Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia
description
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im August 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/08/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/08/01)
@nl
наукова стаття, опублікована в серпні 2007
@uk
مقالة علمية (نشرت في أغسطس 2007)
@ar
name
Evc is a positive mediator of ...... the base of chondrocyte cilia
@ast
Evc is a positive mediator of ...... the base of chondrocyte cilia
@en
Evc is a positive mediator of ...... the base of chondrocyte cilia
@nl
type
label
Evc is a positive mediator of ...... the base of chondrocyte cilia
@ast
Evc is a positive mediator of ...... the base of chondrocyte cilia
@en
Evc is a positive mediator of ...... the base of chondrocyte cilia
@nl
prefLabel
Evc is a positive mediator of ...... the base of chondrocyte cilia
@ast
Evc is a positive mediator of ...... the base of chondrocyte cilia
@en
Evc is a positive mediator of ...... the base of chondrocyte cilia
@nl
P2093
P356
P1433
P1476
Evc is a positive mediator of ...... the base of chondrocyte cilia
@en
P2093
Amy Wilson
Colin Miles
Heiko Peters
Helen J Blair
Judith A Goodship
M Elena Rodriguez-Andres
Maria Jose Blanco
Yu-Ning Liu
P304
P356
10.1242/DEV.007542
P407
P577
2007-08-01T00:00:00Z