Decoding the phosphorylation code in Hedgehog signal transduction - Test2 - elhamkhani - TriplyDB

Decoding the phosphorylation code in Hedgehog signal transduction

Decoding the phosphorylation code in Hedgehog signal transduction

http://www.wikidata.org/entity/Q27021981

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Disruption of G-protein γ5 subtype causes embryonic lethality in mice GSK3β-Dzip1-Rab8 cascade regulates ciliogenesis after mitosis Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development.Smoothened Regulation: A Tale of Two Signals.Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling.Hedgehog-induced phosphorylation by CK1 sustains the activity of Ci/Gli activator A broadly conserved g-protein-coupled receptor kinase phosphorylation mechanism controls Drosophila smoothened activity.The intersection of the extrinsic hedgehog and WNT/wingless signals with the intrinsic Hox code underpins branching pattern and tube shape diversity in the drosophila airways.MiR-218 inhibits multidrug resistance (MDR) of gastric cancer cells by targeting Hedgehog/smoothened.Functional Interaction between HEXIM and Hedgehog Signaling during Drosophila Wing Development.Regulation of Smoothened Phosphorylation and High-Level Hedgehog Signaling Activity by a Plasma Membrane Associated Kinase.Molecular Characterization of Bovine SMO Gene and Effects of Its Genetic Variations on Body Size Traits in Qinchuan Cattle (Bos taurus).Hedgehog induces formation of PKA-Smoothened complexes to promote Smoothened phosphorylation and pathway activation.Smoothened regulation in response to Hedgehog stimulation.Hedgehog signaling and steroidogenesis.The G protein Gαs acts as a tumor suppressor in sonic hedgehog signaling-driven tumorigenesis.Suppressor of fused impedes Ci/Gli nuclear import by opposing Trn/Kapβ2 in Hedgehog signaling.SUMO regulates the activity of Smoothened and Costal-2 in Drosophila Hedgehog signaling.Smoothened is a poor prognosis factor and a potential therapeutic target in glioma.Hedgehog signaling from the primary cilium to the nucleus: an emerging picture of ciliary localization, trafficking and transduction Hedgehog: Multiple Paths for Multiple Roles in Shaping the Brain and Spinal Cord.Decoding Ci: from partial degradation to inhibition.Establishment of basal cell carcinoma animal model in Chinese tree shrew (Tupaia belangeri chinensis).SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development.Hedgehog Signal Transduction: Key Players, Oncogenic Drivers, and Cancer Therapy.CK1 in Developmental Signaling: Hedgehog and Wnt.Hedgehog signalling is required for cell survival in Drosophila wing pouch cells The emerging roles of phosphatases in Hedgehog pathway.The human Smoothened inhibitor PF-04449913 induces exit from quiescence and loss of multipotent Drosophila hematopoietic progenitor cells.The centrosomal deubiquitylase USP21 regulates Gli1 transcriptional activity and stability.Cerebrospinal fluid from patients with amyotrophic lateral sclerosis inhibits sonic hedgehog function.Hrs promotes ubiquitination and mediates endosomal trafficking of smoothened in Drosophila hedgehog signaling.Regulation of Smoothened Trafficking and Hedgehog Signaling by the SUMO Pathway.An intracellular activation of Smoothened that is independent of Hedgehog stimulation in Drosophila.Antagonism between Hedgehog and Wnt signaling pathways regulates tumorigenicity.Sqh is involved in the regulation of Ci stability in Hh signaling pathway.[Structure of the Smoothened receptor].Role of GLI Transcription Factors in Pathogenesis and Their Potential as New Therapeutic Targets Role of canonical Hedgehog signaling pathway in liver Emerging Roles of Sonic Hedgehog in Adult Neurological Diseases: Neurogenesis and Beyond

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P2860

Decoding the phosphorylation code in Hedgehog signal transduction

http://www.wikidata.org/entity/Q27021981

description

2013 nî lūn-bûn

@nan

2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Decoding the phosphorylation code in Hedgehog signal transduction

@ast

Decoding the phosphorylation code in Hedgehog signal transduction

@en

Decoding the phosphorylation code in Hedgehog signal transduction

@nl

type

label

Decoding the phosphorylation code in Hedgehog signal transduction

@ast

Decoding the phosphorylation code in Hedgehog signal transduction

@en

Decoding the phosphorylation code in Hedgehog signal transduction

@nl

prefLabel

Decoding the phosphorylation code in Hedgehog signal transduction

@ast

Decoding the phosphorylation code in Hedgehog signal transduction

@en

Decoding the phosphorylation code in Hedgehog signal transduction

@nl

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Decoding the phosphorylation code in Hedgehog signal transduction

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Jin Jiang

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Yongbin Chen

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

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Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

Evc2 is a positive modulator of Hedgehog signalling that interacts with Evc at the cilia membrane and is also found in the nucleus

Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing

The crosstalk of mTOR/S6K1 and Hedgehog pathways

Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites

Identification of a novel serine/threonine kinase ULK3 as a positive regulator of Hedgehog pathway

The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development

Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt

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186-200

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908684

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10.1038/CR.2013.10

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1022042696

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phosphorylation

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