Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice - Test2 - elhamkhani - TriplyDB

Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice

Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice

http://www.wikidata.org/entity/Q28508807

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Phosphorylation of Tyr1214 within VEGFR-2 triggers the recruitment of Nck and activation of Fyn leading to SAPK2/p38 activation and endothelial cell migration in response to VEGF The myosin motor Myo1c is required for VEGFR2 delivery to the cell surface and for angiogenic signaling Protein kinase D-dependent phosphorylation and nuclear export of histone deacetylase 5 mediates vascular endothelial growth factor-induced gene expression and angiogenesis Endorepellin laminin-like globular 1/2 domains bind Ig3-5 of vascular endothelial growth factor (VEGF) receptor 2 and block pro-angiogenic signaling by VEGFA in endothelial cells Src homology 2 (SH2) domain containing protein tyrosine phosphatase-1 (SHP-1) dephosphorylates VEGF Receptor-2 and attenuates endothelial DNA synthesis, but not migration VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis.Intruders below the radar: molecular pathogenesis of Bartonella spp Vascular endothelial growth factor A: just one of multiple mechanisms for sex-specific vascular development within the testis?The Emerging Regulation of VEGFR-2 in Triple-Negative Breast Cancer Vascular endothelial growth factor and its receptor system: physiological functions in angiogenesis and pathological roles in various diseases Vitreous mediators in retinal hypoxic diseases Vascular permeability--the essentials Quercetin-4'-O-β-D-glucopyranoside (QODG) inhibits angiogenesis by suppressing VEGFR2-mediated signaling in zebrafish and endothelial cells Blood vessels as targets in tumor therapy Phosphorylation of Akt and ERK1/2 is required for VEGF-A/VEGFR2-induced proliferation and migration of lymphatic endothelium VEGF165b Modulates Endothelial VEGFR1-STAT3 Signaling Pathway and Angiogenesis in Human and Experimental Peripheral Arterial Disease.VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd.Chemical modulation of receptor signaling inhibits regenerative angiogenesis in adult zebrafish KIF13B regulates angiogenesis through Golgi to plasma membrane trafficking of VEGFR2 Precancerous stem cells can serve as tumor vasculogenic progenitors.IQGAP1-dependent signaling pathway regulates endothelial cell proliferation and angiogenesis.Lymphoma cell VEGFR2 expression detected by immunohistochemistry predicts poor overall survival in diffuse large B cell lymphoma treated with immunochemotherapy (R-CHOP).Role of c-Cbl-dependent regulation of phospholipase Cgamma1 activation in experimental choroidal neovascularization Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells.Vascular endothelial growth factor signaling in hypoxia and inflammation.Phospholipase Cgamma activation drives increased production of autotaxin in endothelial cells and lysophosphatidic acid-dependent regression.Endothelial cell activation in a VEGF-A gradient: relevance to cell fate decisions.hSulf-1 gene exhibits anticancer efficacy through negatively regulating VEGFR-2 signaling in human cancers VEGFR-1 and VEGFR-2: two non-identical twins with a unique physiognomy A novel role of vascular endothelial cadherin in modulating c-Src activation and downstream signaling of vascular endothelial growth factor Protein kinase C-dependent protein kinase D activation modulates ERK signal pathway and endothelial cell proliferation by vascular endothelial growth factor Design of growth factor sequestering biomaterials κ Opioid receptor ligands regulate angiogenesis in development and in tumours.Tyrosine Kinase Receptor Flt/VEGFR Family: Its Characterization Related to Angiogenesis and Cancer.Emerging roles of post-translational modifications in signal transduction and angiogenesis Priming of the vascular endothelial growth factor signaling pathway by thrombospondin-1, CD36, and spleen tyrosine kinase.Vascular endothelial growth factor receptors: molecular mechanisms of activation and therapeutic potentials.The docking protein FRS2α is a critical regulator of VEGF receptors signaling Involvement of Flt-1 (VEGF receptor-1) in cancer and preeclampsia.Vascular endothelial growth factor receptor 2 direct interaction with nephrin links VEGF-A signals to actin in kidney podocytes

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P2860

Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice

http://www.wikidata.org/entity/Q28508807

description

2005 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի հունվարին հրատարակված գիտական հոդված

@hy

article publié dans les Procee ...... f the United States of America

@fr

artículu científicu espublizáu en 2005

@ast

im Januar 2005 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 2005/01/25)

@sk

vědecký článek publikovaný v roce 2005

@cs

wetenschappelijk artikel (gepubliceerd op 2005/01/25)

@nl

наукова стаття, опублікована в січні 2005

@uk

name

Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice

@ast

Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice

@en

Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice

@nl

type

label

Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice

@ast

Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice

@en

Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice

@nl

prefLabel

Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice

@ast

Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice

@en

Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice

@nl

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P356

PNAS.0404984102

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice

@en

P2093

Kaori Ohgimoto

http://www.w3.org/2001/XMLSchema#string

Masabumi Shibuya

http://www.w3.org/2001/XMLSchema#string

Nobuaki Yoshida

http://www.w3.org/2001/XMLSchema#string

Yoshiko Sakurai

http://www.w3.org/2001/XMLSchema#string

Yuki Kataoka

http://www.w3.org/2001/XMLSchema#string

P2860

Autophosphorylation of KDR in the kinase domain is required for maximal VEGF-stimulated kinase activity and receptor internalization

A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells

Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor

Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family

The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

The biology of VEGF and its receptors

Biological activity and phosphorylation sites of the bacterially expressed cytosolic domain of the KDR VEGF-receptor

Interactions of FLT-1 and KDR with phospholipase C gamma: identification of the phosphotyrosine binding sites

The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration

Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

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1076–1081

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scholarly article

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2507984

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P356

10.1073/PNAS.0404984102

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P407

P433

4

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P478

102

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P577

2005-01-25T00:00:00Z

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P5875

8087871

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P698

15644447

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P921

Vascular endothelial growth factor receptor 2

P932

545830

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