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Site specific mutation of the Zic2 locus by microinjection of TALEN mRNA in mouse CD1, C3H and C57BL/6J oocytesPhysical and functional interactions between Zic and Gli proteinsHow to form and close the brain: insight into the mechanism of cranial neural tube closure in mammalsValproic acid teratogenicity: a toxicogenomics approachUnique alterations of an ultraconserved non-coding element in the 3'UTR of ZIC2 in holoprosencephalyTowards a cellular and molecular understanding of neurulationRegulatory mechanisms for neural crest formationMolecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteinsZic2 regulates the expression of Sert to modulate eye-specific refinement at the visual targetsFunctional role of Zic2 phosphorylation in transcriptional regulationRines/RNF180, a novel RING finger gene-encoded product, is a membrane-bound ubiquitin ligaseBat Accelerated Regions Identify a Bat Forelimb Specific Enhancer in the HoxD LocusThe ZIC gene family encodes multi-functional proteins essential for patterning and morphogenesis.Spatiotemporal expression of Zic genes during vertebrate inner ear development.Zic2 hypomorphic mutant mice as a schizophrenia model and ZIC2 mutations identified in schizophrenia patientsLhx2 regulates the development of the forebrain hem system.Nodal signaling is required for closure of the anterior neural tube in zebrafish.Transcription factors Zic1 and Zic2 bind and transactivate the apolipoprotein E gene promoter.Holoprosencephaly.Expression of the zic1, zic2, zic3, and zic4 genes in early chick embryosThe molecular genetics of holoprosencephaly.Dysregulation of the SIRT1/OCT6 Axis Contributes to Environmental Stress-Induced Neural Induction Defects.Targeted disruption of Tgif, the mouse ortholog of a human holoprosencephaly gene, does not result in holoprosencephaly in mice.Sexual phenotype differences in zic2 mRNA abundance in the preoptic area of a protogynous teleost, Thalassoma bifasciatum.The role of Zic genes in inner ear development in the mouse: Exploring mutant mouse phenotypes.Midline and laterality defects: left and right meet in the middle.Neural induction takes a transcriptional twist.ZIC2-dependent transcriptional regulation is mediated by DNA-dependent protein kinase, poly(ADP-ribose) polymerase, and RNA helicase A.A role for Zic1 and Zic2 in Myf5 regulation and somite myogenesis.Molecular and comparative genetics of mental retardation.Folic acid supplementation can adversely affect murine neural tube closure and embryonic survival.The genetic basis of mammalian neurulation.Mutations in ZIC2 in human holoprosencephaly: description of a novel ZIC2 specific phenotype and comprehensive analysis of 157 individuals.Comparison of mutation findings in ZIC2 between microform and classical holoprosencephaly in a Brazilian cohortBrain enhancer activities at the gene-poor 5p14.1 autism-associated locus.The full spectrum of holoprosencephaly-associated mutations within the ZIC2 gene in humans predicts loss-of-function as the predominant disease mechanism.Shh/Boc signaling is required for sustained generation of ipsilateral projecting ganglion cells in the mouse retina.FGF signaling is strictly required to maintain early telencephalic precursor cell survivalZic2 regulates retinal ganglion cell axon avoidance of ephrinB2 through inducing expression of the guidance receptor EphB1.Pathogenesis of holoprosencephaly
P2860
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P2860
description
2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2000
@ast
im Februar 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/02/15)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/02/15)
@nl
наукова стаття, опублікована в лютому 2000
@uk
name
Zic2 regulates the kinetics of neurulation
@ast
Zic2 regulates the kinetics of neurulation
@en
Zic2 regulates the kinetics of neurulation
@nl
type
label
Zic2 regulates the kinetics of neurulation
@ast
Zic2 regulates the kinetics of neurulation
@en
Zic2 regulates the kinetics of neurulation
@nl
prefLabel
Zic2 regulates the kinetics of neurulation
@ast
Zic2 regulates the kinetics of neurulation
@en
Zic2 regulates the kinetics of neurulation
@nl
P2093
P2860
P3181
P356
P1476
Zic2 regulates the kinetics of neurulation
@en
P2093
K. Mikoshiba
T. Sugimoto
P2860
P304
P3181
P356
10.1073/PNAS.97.4.1618
P407
P577
2000-02-15T00:00:00Z