Targeted disruption of the Walker-Warburg syndrome gene Pomt1 in mouse results in embryonic lethality
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Walker-Warburg syndromeO Mannosylation of alpha-dystroglycan is essential for lymphocytic choriomeningitis virus receptor functionThe glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated α-dystroglycan functional glycosylationTumor suppressor function of laminin-binding alpha-dystroglycan requires a distinct beta3-N-acetylglucosaminyltransferaseMouse fukutin deletion impairs dystroglycan processing and recapitulates muscular dystrophyMammalian O-mannosylation: unsolved questions of structure/functionO-Mannosylation and human diseaseSwimming into prominence: the zebrafish as a valuable tool for studying human myopathies and muscular dystrophies.Mutations in POMGNT1 cause non-syndromic retinitis pigmentosaCharacterization of the LARGE family of putative glycosyltransferases associated with dystroglycanopathiesProtein O-Glucosyltransferase 1 (POGLUT1) Promotes Mouse Gastrulation through Modification of the Apical Polarity Protein CRUMBS2Expression of the murine Pomt1 gene in both the developing brain and adult muscle tissues and its relationship with clinical aspects of Walker-Warburg syndromeXylosyl- and glucuronyltransferase functions of LARGE in α-dystroglycan modification are conserved in LARGE2A POGLUT1 mutation causes a muscular dystrophy with reduced Notch signaling and satellite cell loss.Characterization of the PMT gene family in Cryptococcus neoformans.Zebrafish models for human FKRP muscular dystrophiesThe dystroglycanopathies: the new disorders of O-linked glycosylationIncreased apoptosis of myoblasts in Drosophila model for the Walker-Warburg syndromePhysical and functional association of human protein O-mannosyltransferases 1 and 2.Genetic defects in the human glycome.The twisted gene encodes Drosophila protein O-mannosyltransferase 2 and genetically interacts with the rotated abdomen gene encoding Drosophila protein O-mannosyltransferase 1.Protein O-mannosylation: conserved from bacteria to humans.Dynamic regulation of alpha-dystroglycan in mouse placenta.Protein Glycosylation in Aspergillus fumigatus Is Essential for Cell Wall Synthesis and Serves as a Promising Model of Multicellular Eukaryotic Development.Hansenula polymorpha Pmt4p Plays Critical Roles in O-Mannosylation of Surface Membrane Proteins and Participates in Heteromeric Complex Formation.Membrane association is a determinant for substrate recognition by PMT4 protein O-mannosyltransferases.Protein O-Mannosylation in the Murine Brain: Occurrence of Mono-O-Mannosyl Glycans and Identification of New SubstratesDevelopmental expression of the neuron-specific N-acetylglucosaminyltransferase Vb (GnT-Vb/IX) and identification of its in vivo glycan products in comparison with those of its paralog, GnT-VO-Mannosyltransferase 1 in Aspergillus fumigatus (AfPmt1p) is crucial for cell wall integrity and conidium morphology, especially at an elevated temperature.Mechanisms of disease: congenital muscular dystrophies-glycosylation takes center stage.Mapping the O-Mannose Glycoproteome in Saccharomyces cerevisiaeConditional knockout of protein O-mannosyltransferase 2 reveals tissue-specific roles of O-mannosyl glycosylation in brain development.Biochemical and biophysical changes underlie the mechanisms of basement membrane disruptions in a mouse model of dystroglycanopathy.Congenital muscular dystrophies involving the O-mannose pathway.Muscular dystrophies due to defective glycosylation of dystroglycan.Brain and eye malformations resembling Walker-Warburg syndrome are recapitulated in mice by dystroglycan deletion in the epiblastRole of unusual O-glycans in intercellular signalingTherapeutic possibilities in the autosomal recessive limb-girdle muscular dystrophies.Protein O-mannosylation is crucial for E-cadherin-mediated cell adhesion.Protein O-mannosylation in animal development and physiology: from human disorders to Drosophila phenotypes
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P2860
Targeted disruption of the Walker-Warburg syndrome gene Pomt1 in mouse results in embryonic lethality
description
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
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artículu científicu espublizáu en 2004
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im September 2004 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2004/09/28)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/09/28)
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наукова стаття, опублікована у вересні 2004
@uk
name
Targeted disruption of the Wal ...... results in embryonic lethality
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Targeted disruption of the Wal ...... results in embryonic lethality
@en
Targeted disruption of the Wal ...... results in embryonic lethality
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type
label
Targeted disruption of the Wal ...... results in embryonic lethality
@ast
Targeted disruption of the Wal ...... results in embryonic lethality
@en
Targeted disruption of the Wal ...... results in embryonic lethality
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prefLabel
Targeted disruption of the Wal ...... results in embryonic lethality
@ast
Targeted disruption of the Wal ...... results in embryonic lethality
@en
Targeted disruption of the Wal ...... results in embryonic lethality
@nl
P2093
P2860
P50
P3181
P356
P1476
Targeted disruption of the Wal ...... results in embryonic lethality
@en
P2093
Antonio Coloma
Belén Prados
Gerhard K. H. Przemeck
Ingrid Renner-Müller
Jesús Cruces
M. Carmen Valero
Mark Lommel
Sabine Strahl
Tobias Willer
Widmar Tanner
P2860
P304
14126–14131
P3181
P356
10.1073/PNAS.0405899101
P407
P577
2004-09-28T00:00:00Z