The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues
about
Titanium dioxide (TiO2) nanoparticles preferentially induce cell death in transformed cells in a Bak/Bax-independent fashionHypoxia and defective apoptosis drive genomic instability and tumorigenesisMonosaccharide digitoxin derivative sensitize human non-small cell lung cancer cells to anoikis through Mcl-1 proteasomal degradationTumor necrosis factor-alpha induces Bax-Bak interaction and apoptosis, which is inhibited by adenovirus E1B 19KBAD is a pro-survival factor prior to activation of its pro-apoptotic functionInteraction of F1L with the BH3 domain of Bak is responsible for inhibiting vaccinia-induced apoptosisProapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.Heterodimerization of BAK and MCL-1 activated by detergent micellesBH3 domains other than Bim and Bid can directly activate Bax/BakASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathwayThe vaccinia virus protein F1L interacts with Bim and inhibits activation of the pro-apoptotic protein BaxChemical genomics identifies small-molecule MCL1 repressors and BCL-xL as a predictor of MCL1 dependencyThe tyrosine kinase Lck is a positive regulator of the mitochondrial apoptosis pathway by controlling Bak expressionVaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligandsMutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosisMAP-1 is a mitochondrial effector of Bax.Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosisThe Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinaseTumor suppressors: enhancers or suppressors of regeneration?The Bcl-2 apoptotic switch in cancer development and therapySmall-molecule Bcl-2 antagonists as targeted therapy in oncologyProapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activityInhibition of ubiquitin-mediated degradation of MOAP-1 by apoptotic stimuli promotes Bax function in mitochondriaRole of Bax in resveratrol-induced apoptosis of colorectal carcinoma cells.Oncogenic MicroRNAs: Key Players in Malignant TransformationNecroptotic Cell Death Signaling and Execution Pathway: Lessons from Knockout MiceBH3 profiling--measuring integrated function of the mitochondrial apoptotic pathway to predict cell fate decisionsReactive oxygen species, apoptosis, and mitochondrial dysfunction in hearing loss.A High-Throughput Small Molecule Screen for C. elegans Linker Cell Death InhibitorsEstrogen-dependent proteolytic cleavage of semaphorin 4D and plexin-B1 enhances semaphorin 4D-induced apoptosis during postnatal vaginal remodeling in pubescent miceBH3 peptides induce mitochondrial fission and cell death independent of BAX/BAKBID-induced structural changes in BAK promote apoptosisA1/Bfl-1 in leukocyte development and cell deathHumanin binds and nullifies Bid activity by blocking its activation of Bax and BakInactivation of caspase-8 on mitochondria of Bcl-xL-expressing MCF7-Fas cells: role for the bifunctional apoptosis regulator proteinTCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xLBuilding blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosisDamage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate.Regulation of mitochondrial ceramide distribution by members of the BCL-2 familyMitochondria: diversity in the regulation of the NLRP3 inflammasome.
P2860
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P2860
The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年學術文章
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name
The combined functions of proa ...... evelopment of multiple tissues
@ast
The combined functions of proa ...... evelopment of multiple tissues
@en
The combined functions of proa ...... evelopment of multiple tissues
@nl
type
label
The combined functions of proa ...... evelopment of multiple tissues
@ast
The combined functions of proa ...... evelopment of multiple tissues
@en
The combined functions of proa ...... evelopment of multiple tissues
@nl
prefLabel
The combined functions of proa ...... evelopment of multiple tissues
@ast
The combined functions of proa ...... evelopment of multiple tissues
@en
The combined functions of proa ...... evelopment of multiple tissues
@nl
P2093
P2860
P3181
P1433
P1476
The combined functions of proa ...... evelopment of multiple tissues
@en
P2093
A. J. Ross
C. B. Thompson
D. M. Adelman
G. R. MacGregor
H. A. Shiels
J. A. Golden
P2860
P304
P3181
P356
10.1016/S1097-2765(00)00136-2
P577
2000-12-01T00:00:00Z