Cloning and characterization of a 72-kDa inositol-polyphosphate 5-phosphatase localized to the Golgi network
about
Identification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic reticulum and translocates to membrane ruffles ...Mutations in KIF7 link Joubert syndrome with Sonic Hedgehog signaling and microtubule dynamicsINPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouseCellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteinsInositol polyphosphate 5-phosphatases; new players in the regulation of cilia and ciliopathiesPhosphoinositides: tiny lipids with giant impact on cell regulationThe yeast inositol polyphosphate 5-phosphatase Inp54p localizes to the endoplasmic reticulum via a C-terminal hydrophobic anchoring tail: regulation of secretion from the endoplasmic reticulum.The inositol polyphosphate 5-phosphatase, PIPP, Is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation.Genetic Variants Associated With Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium.A novel receptor-mediated regulation mechanism of type I inositol polyphosphate 5-phosphatase by calcium/calmodulin-dependent protein kinase II phosphorylation.Characterization of an adapter subunit to a phosphatidylinositol (3)P 3-phosphatase: identification of a myotubularin-related protein lacking catalytic activityReactive oxygen species enhance insulin sensitivityThe structure of phosphoinositide phosphatases: Insights into substrate specificity and catalysis.Rapidly inducible changes in phosphatidylinositol 4,5-bisphosphate levels influence multiple regulatory functions of the lipid in intact living cellsThe Shc-binding site of the betac subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesisArf-like Protein 3 (ARL3) Regulates Protein Trafficking and Ciliogenesis in Mouse Photoreceptors.Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P(2).INPP5E regulates phosphoinositide-dependent cilia transition zone function.Inositol lipid phosphatases in membrane trafficking and human disease.Phosphatidylinositol 3-phosphate [PtdIns3P] is generated at the plasma membrane by an inositol polyphosphate 5-phosphatase: endogenous PtdIns3P can promote GLUT4 translocation to the plasma membrane.Phosphatidylinositolphosphate phosphatase activities and cancer.The Joubert Syndrome Protein Inpp5e Controls Ciliogenesis by Regulating Phosphoinositides at the Apical Membrane.Autophagosome-lysosome fusion in neurons requires INPP5E, a protein associated with Joubert syndrome.Detection of novel intracellular agonist responsive pools of phosphatidylinositol 3,4-bisphosphate using the TAPP1 pleckstrin homology domain in immunoelectron microscopy.Autophagosome-lysosome fusion: PIs to the rescue.Evidence of a role of inositol polyphosphate 5-phosphatase INPP5E in cilia formation in zebrafishLarge scale screening for novel rab effectors reveals unexpected broad Rab binding specificity.A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma.PI(4;5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membraneInpp5e suppresses polycystic kidney disease via inhibition of PI3K/Akt-dependent mTORC1 signaling.Relationship Between INPP5E Gene Expression and Embryonic Neural Development in a Mouse Model of Neural Tube Defect.The PH domain from the Toxoplasma gondii PH-containing protein-1 (TgPH1) serves as an ectopic reporter of phosphatidylinositol 3-phosphate in mammalian cells.
P2860
Q24292896-C0D51099-CE93-4A1A-9424-498CC98D7D83Q24305196-4AD556FF-21B2-46F8-B694-8064B130D1B4Q24323384-BBBAB69B-50B6-478D-A0C5-E5474523B438Q24532611-8C85515D-0E16-4D6F-BDB6-6A56E6D78C4DQ27012842-624EE7CB-A97A-4F08-8043-5E4199D70309Q27012953-78A764DA-C41F-404A-A121-E218C74D8EE7Q27940135-89B5BF56-3E42-4DC1-84CF-3625EF1D26BDQ28583817-F6074B07-525C-4856-B48F-EFCAE84AFC5DQ30301097-3A2DF7A1-B837-43DA-8190-F7810C99C20AQ30702659-3A1BA1AA-A863-4F67-83E2-3C7B3C9B5638Q33932541-87D80134-C68B-4F02-9B07-24FC7DAE1F98Q33941647-EB42BD74-43A9-4FB8-B050-04921EA9293BQ35225936-2CCCD970-36B6-40F9-B31D-A4D82D177299Q36118986-76516B8B-8E2C-43F4-BA61-FFD23500D50EQ36141626-39C4FF94-1D1D-4859-ACDA-F0D39D12CD97Q36727473-EB9BED5E-2741-41E3-AA93-DF3F2BC35508Q37292741-8211CC15-A0A9-4782-8BD9-97A4C93458C3Q37576577-82A9EE32-60F3-45C4-BD02-9568B8495CC4Q38223317-E7BE489E-1C9D-4FE9-9E1A-F59CC562022DQ38409013-21AED60F-282A-4DE2-9456-946CF89CE07FQ38572786-AEB0EB8D-5DA0-4528-AB16-DFC0347DF00DQ39612709-E7D8FC25-C15C-439C-B703-DF9AFBABFBFFQ39658143-617FEBAB-219B-4C91-9F18-113FC5C6B054Q40618985-23FAE084-C37F-4C42-B505-637FE71C7F79Q40991344-076B0CEF-D760-4C85-AF13-D9A0F18FBCC9Q42070844-20136D73-2A4F-4E3E-90E9-8D2C6BB981BAQ46767758-0290D0EE-5E83-4380-A83D-6D915DA504C6Q48222748-1E4D0CCD-4394-4C55-906A-10DB0C66AF04Q50293915-C56631CE-88ED-4DF6-A9AB-2E27EE45D2A4Q50481460-D77E08E0-5F65-4E3D-A151-D4CF03B3C443Q54974024-16CE6D92-E6A9-4D90-83A0-AC9349A627D0Q55160467-CBA80023-6A01-4F39-B652-2018824EA4B1
P2860
Cloning and characterization of a 72-kDa inositol-polyphosphate 5-phosphatase localized to the Golgi network
description
2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2000
@ast
im August 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/08/04)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/08/04)
@nl
наукова стаття, опублікована в серпні 2000
@uk
name
Cloning and characterization o ...... localized to the Golgi network
@ast
Cloning and characterization o ...... localized to the Golgi network
@en
Cloning and characterization o ...... localized to the Golgi network
@nl
type
label
Cloning and characterization o ...... localized to the Golgi network
@ast
Cloning and characterization o ...... localized to the Golgi network
@en
Cloning and characterization o ...... localized to the Golgi network
@nl
prefLabel
Cloning and characterization o ...... localized to the Golgi network
@ast
Cloning and characterization o ...... localized to the Golgi network
@en
Cloning and characterization o ...... localized to the Golgi network
@nl
P2093
P2860
P356
P1476
Cloning and characterization o ...... localized to the Golgi network
@en
P2093
A. M. Kong
C. A. Mitchell
C. J. O'Malley
C. J. Speed
K. L. Loveland
L. M. Ooms
M. J. Layton
P2860
P304
24052–24064
P356
10.1074/JBC.M000874200
P407
P577
2000-08-04T00:00:00Z