The Connectivity Map: a new tool for biomedical research
about
Genome-scale screening of drug-target associations relevant to Ki using a chemogenomics approachCombinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90Functional genomic analysis of amniotic fluid cell-free mRNA suggests that oxidative stress is significant in Down syndrome fetusesComputational approaches in target identification and drug discoveryStepping into the omics era: Opportunities and challenges for biomaterials science and engineeringTranslational Bioinformatics: Past, Present, and FutureSystems Pharmacology in Small Molecular Drug DiscoveryA survey on the computational approaches to identify drug targets in the postgenomic eraTargeted therapy in gastric cancer: personalizing cancer treatment based on patient genomeDrug repositioning approaches for the discovery of new therapeutics for Alzheimer's diseasePREDICT: a method for inferring novel drug indications with application to personalized medicineToward the Replacement of Animal Experiments through the Bioinformatics-driven Analysis of 'Omics' Data from Human Cell CulturesUsing Pharmacogenomic Databases for Discovering Patient-Target Genes and Small Molecule Candidates to Cancer TherapyPrediction of pharmacological and xenobiotic responses to drugs based on time course gene expression profilesGene expression signature-based screening identifies new broadly effective influenza a antiviralsBuilding disease-specific drug-protein connectivity maps from molecular interaction networks and PubMed abstractsHuman disease-drug network based on genomic expression profilesThe Mycobacterium tuberculosis drugome and its polypharmacological implicationsTranscriptional profiling of the dose response: a more powerful approach for characterizing drug activitiesIdentification of candidate small-molecule therapeutics to cancer by gene-signature perturbation in connectivity mappingGene expression signature analysis identifies vorinostat as a candidate therapy for gastric cancerLarge-scale elucidation of drug response pathways in humansUsing functional signatures to identify repositioned drugs for breast, myelogenous leukemia and prostate cancerIntegrating constitutive gene expression and chemoactivity: mining the NCI60 anticancer screenLeveraging systems biology approaches in clinical pharmacologyDiscovering hidden connections among diseases, genes and drugs based on microarray expression profiles with negative-term filteringData Mining Approaches for Genomic Biomarker Development: Applications Using Drug Screening Data from the Cancer Genome Project and the Cancer Cell Line EncyclopediaCancer Biology, Toxicology and Alternative Methods Development Go Hand-in-HandA Semi-Supervised Approach for Refining Transcriptional Signatures of Drug Response and Repositioning PredictionsA Systematic Framework for Drug Repositioning from Integrated Omics and Drug Phenotype Profiles Using Pathway-Drug NetworkSystematic Quality Control Analysis of LINCS DataApplication of the TGx-28.65 transcriptomic biomarker to classify genotoxic and non-genotoxic chemicals in human TK6 cells in the presence of rat liver S9High throughput toxicity screening and intracellular detection of nanomaterialsTranscriptomic characterization of the novel avian-origin influenza A (H7N9) virus: specific host response and responses intermediate between avian (H5N1 and H7N7) and human (H3N2) viruses and implications for treatment optionsHarnessing systems biology approaches to engineer functional microvascular networksRational drug repositioning guided by an integrated pharmacological network of protein, disease and drug.Early repositioning through compound set enrichment analysis: a knowledge-recycling strategy.Human mucosal in vivo transcriptome responses to three lactobacilli indicate how probiotics may modulate human cellular pathways.Transcriptional data: a new gateway to drug repositioning?Finding the targets of a drug by integration of gene expression data with a protein interaction network.
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P2860
The Connectivity Map: a new tool for biomedical research
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The Connectivity Map: a new tool for biomedical research
@ast
The Connectivity Map: a new tool for biomedical research
@en
The Connectivity Map: a new tool for biomedical research
@nl
type
label
The Connectivity Map: a new tool for biomedical research
@ast
The Connectivity Map: a new tool for biomedical research
@en
The Connectivity Map: a new tool for biomedical research
@nl
prefLabel
The Connectivity Map: a new tool for biomedical research
@ast
The Connectivity Map: a new tool for biomedical research
@en
The Connectivity Map: a new tool for biomedical research
@nl
P3181
P356
P1476
The Connectivity Map: a new tool for biomedical research
@en
P2093
Justin Lamb
P2860
P2888
P3181
P356
10.1038/NRC2044
P407
P577
2007-01-01T00:00:00Z
P5875
P6179
1012791529