Automated NMR fragment based screening identified a novel interface blocker to the LARG/RhoA complex
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Process of Fragment-Based Lead Discovery-A Perspective from NMRStructural Mechanisms and Drug Discovery Prospects of Rho GTPasesNMR Fragment Screening Hit Induces Plasticity of BRD7/9 BromodomainsThe polar warhead of a TRIM24 bromodomain inhibitor rearranges a water-mediated interaction network.Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions.NMR-based platform for fragment-based lead discovery used in screening BRD4-targeted compoundsScreening-based approaches to identify small molecules that inhibit protein-protein interactions.RSK2 drives cell motility by serine phosphorylation of LARG and activation of Rho GTPases.A small molecule inhibitor of Rheb selectively targets mTORC1 signaling.
P2860
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P2860
Automated NMR fragment based screening identified a novel interface blocker to the LARG/RhoA complex
description
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2014 թվականին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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name
Automated NMR fragment based s ...... ocker to the LARG/RhoA complex
@ast
Automated NMR fragment based s ...... ocker to the LARG/RhoA complex
@en
Automated NMR fragment based s ...... ocker to the LARG/RhoA complex
@nl
type
label
Automated NMR fragment based s ...... ocker to the LARG/RhoA complex
@ast
Automated NMR fragment based s ...... ocker to the LARG/RhoA complex
@en
Automated NMR fragment based s ...... ocker to the LARG/RhoA complex
@nl
prefLabel
Automated NMR fragment based s ...... ocker to the LARG/RhoA complex
@ast
Automated NMR fragment based s ...... ocker to the LARG/RhoA complex
@en
Automated NMR fragment based s ...... ocker to the LARG/RhoA complex
@nl
P2093
P2860
P3181
P1433
P1476
Automated NMR fragment based s ...... ocker to the LARG/RhoA complex
@en
P2093
David Snyderman
Rongsheng Ma
Ryan Sasaki
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0088098
P407
P50
P577
2014-01-01T00:00:00Z