The free energy profile of tubulin straight-bent conformational changes, with implications for microtubule assembly and drug discovery
about
Maintenance of electrostatic stabilization in altered tubulin lateral contacts may facilitate formation of helical filaments in foraminiferaTubulin bond energies and microtubule biomechanics determined from nanoindentation in silico.Designing and Testing of Novel Taxanes to Probe the Highly Complex Mechanisms by Which Taxanes Bind to Microtubules and Cause Cytotoxicity to Cancer CellsThe synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity.Elucidating the mechanism of action of the clinically approved taxanes: a comprehensive comparison of local and allosteric effects.The subtle allostery of microtubule dynamics.Microtubule assembly governed by tubulin allosteric gain in flexibility and lattice induced fit.Tubulin's response to external electric fields by molecular dynamics simulations
P2860
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P2860
The free energy profile of tubulin straight-bent conformational changes, with implications for microtubule assembly and drug discovery
description
2014 nî lūn-bûn
@nan
2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
The free energy profile of tub ...... le assembly and drug discovery
@ast
The free energy profile of tub ...... le assembly and drug discovery
@en
The free energy profile of tub ...... le assembly and drug discovery
@nl
type
label
The free energy profile of tub ...... le assembly and drug discovery
@ast
The free energy profile of tub ...... le assembly and drug discovery
@en
The free energy profile of tub ...... le assembly and drug discovery
@nl
prefLabel
The free energy profile of tub ...... le assembly and drug discovery
@ast
The free energy profile of tub ...... le assembly and drug discovery
@en
The free energy profile of tub ...... le assembly and drug discovery
@nl
P2093
P2860
P3181
P1476
The free energy profile of tub ...... le assembly and drug discovery
@en
P2093
David A Agard
Lili X Peng
Massimiliano Bonomi
Monica T Hsu
P2860
P304
P3181
P356
10.1371/JOURNAL.PCBI.1003464
P407
P577
2014-02-01T00:00:00Z