Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection
about
Reappearance from Obscurity: Mammalian Rad52 in Homologous RecombinationDrugging the Cancers Addicted to DNA Repair.Human RAD52 interactions with replication protein A and the RAD51 presynaptic complex.Small-molecule inhibitors identify the RAD52-ssDNA interaction as critical for recovery from replication stress and for survival of BRCA2 deficient cellsAberrant DNA Double-strand Break Repair Threads in Breast Carcinoma: Orchestrating Genomic Insult Survival.Personalised Medicine: Genome Maintenance Lessons Learned from Studies in Yeast as a Model Organism.Tracking metastatic breast cancer: the future of biology in biosensors.Corrupting the DNA damage response: a critical role for Rad52 in tumor cell survivalHomologous recombination in budding yeast expressing the human RAD52 gene reveals a Rad51-independent mechanism of conservative double-strand break repair.Replication fork reversal triggers fork degradation in BRCA2-defective cells.The endonuclease EEPD1 mediates synthetic lethality in RAD52-depleted BRCA1 mutant breast cancer cells.A composite docking approach for the identification and characterization of ectosteric inhibitors of cathepsin K.Small-Molecule Inhibitors Targeting DNA Repair and DNA Repair Deficiency in Research and Cancer Therapy.Synthetic lethality in DNA repair network: A novel avenue in targeted cancer therapy and combination therapeutics.Advances in therapeutic targeting of the DNA damage response in cancer.
P2860
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P2860
Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection
description
2016 nî lūn-bûn
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2016 թուականին հրատարակուած գիտական յօդուած
@hyw
2016 թվականին հրատարակված գիտական հոդված
@hy
2016年の論文
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2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
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name
Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection
@ast
Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection
@en
Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection
@nl
type
label
Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection
@ast
Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection
@en
Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection
@nl
prefLabel
Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection
@ast
Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection
@en
Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection
@nl
P2093
P2860
P3181
P1433
P1476
Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection
@en
P2093
Daniel L McElroy
David A Ostrov
Katherine Sullivan
Kimberly Cramer-Morales
Kimberly Haas
Robert Hromas
Tomasz Skorski
Wayne Childers
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0147230
P407
P577
2016-01-01T00:00:00Z