Small-molecule inhibitors identify the RAD52-ssDNA interaction as critical for recovery from replication stress and for survival of BRCA2 deficient cells
about
Reappearance from Obscurity: Mammalian Rad52 in Homologous RecombinationDrugging the Cancers Addicted to DNA Repair.Human RAD52 Captures and Holds DNA Strands, Increases DNA Flexibility, and Prevents Melting of Duplex DNA: Implications for DNA RecombinationSLX4 Prevents GEN1-Dependent DSBs During DNA Replication Arrest Under Pathological Conditions in Human Cells.Replication fork reversal triggers fork degradation in BRCA2-defective cells.The endonuclease EEPD1 mediates synthetic lethality in RAD52-depleted BRCA1 mutant breast cancer cells.Small-Molecule Inhibitors Targeting DNA Repair and DNA Repair Deficiency in Research and Cancer Therapy.Integrating Experimental and In Silico HTS in the Discovery of Inhibitors of Protein-Nucleic Acid Interactions.Phosphorylation by CK2 regulates MUS81/EME1 in mitosis and after replication stress.New Insights Into DNA Helicases as Druggable Targets for Cancer Therapy
P2860
Q28074245-CEB91D49-1D15-4C44-A101-CC884BA1694BQ33702497-4B59C7BE-6921-45F8-866F-69F8A6DD7DB0Q37736341-F8066B23-AB82-43C7-945F-D1D739015BD7Q40293893-2BD5B897-562A-4E29-8609-0C7AF43C7966Q42379022-09683753-AD39-43DB-9365-200FC11516A4Q45898863-F71DC7CF-D8A3-4527-B083-9254D2F58000Q47761787-13DAB2C8-D130-47AD-92A1-A0EF7F7163AAQ52361300-53532015-30B6-49F0-883C-13E51DAFAD05Q54977571-9E0DF6A7-FEEA-4415-ADCE-E522D555E04FQ56476152-E3DCBFD6-4610-44C7-AF82-5D8651D3C0C8
P2860
Small-molecule inhibitors identify the RAD52-ssDNA interaction as critical for recovery from replication stress and for survival of BRCA2 deficient cells
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 19 July 2016
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Small-molecule inhibitors iden ...... vival of BRCA2 deficient cells
@en
Small-molecule inhibitors iden ...... ival of BRCA2 deficient cells.
@nl
type
label
Small-molecule inhibitors iden ...... vival of BRCA2 deficient cells
@en
Small-molecule inhibitors iden ...... ival of BRCA2 deficient cells.
@nl
prefLabel
Small-molecule inhibitors iden ...... vival of BRCA2 deficient cells
@en
Small-molecule inhibitors iden ...... ival of BRCA2 deficient cells.
@nl
P2093
P2860
P50
P356
P1433
P1476
Small-molecule inhibitors iden ...... vival of BRCA2 deficient cells
@en
P2093
Andrea Diaz
Brandon G Koch
Eva Malacaria
Fletcher E Bain
Laura Folly da Silva Constantino
M Ashley Spies
Sarah R Hengel
P2860
P356
10.7554/ELIFE.14740
P407
P577
2016-07-19T00:00:00Z