Spatial mapping of the neurite and soma proteomes reveals a functional Cdc42/Rac regulatory network - Test2 - elhamkhani - TriplyDB

Spatial mapping of the neurite and soma proteomes reveals a functional Cdc42/Rac regulatory network

Spatial mapping of the neurite and soma proteomes reveals a functional Cdc42/Rac regulatory network

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Computer vision profiling of neurite outgrowth dynamics reveals spatiotemporal modularity of Rho GTPase signaling Growth cone MKK7 mRNA targeting regulates MAP1b-dependent microtubule bundling to control neurite elongation Growth Cone Localization of the mRNA Encoding the Chromatin Regulator HMGN5 Modulates Neurite Outgrowth.Two distinct filopodia populations at the growth cone allow to sense nanotopographical extracellular matrix cues to guide neurite outgrowth Structures of PHR Domains from Mus musculus Phr1 (Mycbp2) Explain the Loss-of-Function Mutation (Gly1092→Glu) of the C. elegans Ortholog RPM-1 The contribution of intrinsically disordered regions to protein function, cellular complexity, and human disease The inverse F-BAR domain protein srGAP2 acts through srGAP3 to modulate neuronal differentiation and neurite outgrowth of mouse neuroblastoma cells Structural History of Human SRGAP2 Proteins The N-terminal DH-PH domain of Trio induces cell spreading and migration by regulating lamellipodia dynamics in a Rac1-dependent fashion.Focal adhesion kinase modulates Cdc42 activity downstream of positive and negative axon guidance cues Spatial proteomic and phospho-proteomic organization in three prototypical cell migration modes.Regulation of protein levels in subcellular domains through mRNA transport and localized translation.Neuroproteomics approaches to decipher neuronal regeneration and degeneration.Functional complexity of the axonal growth cone: a proteomic analysis.Asymmetric mRNA localization contributes to fidelity and sensitivity of spatially localized systems Studies on the morphology and spreading of human endothelial cells define key inter- and intramolecular interactions for talin1.PEAK1, a novel kinase target in the fight against cancer.An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke.The trip of the tip: understanding the growth cone machinery.Spatial phosphoprotein profiling reveals a compartmentalized extracellular signal-regulated kinase switch governing neurite growth and retraction Filopodia: Nanodevices that sense nanotopographic ECM cues to orient neurite outgrowth Localized Rho GTPase activation regulates RNA dynamics and compartmentalization in tumor cell protrusions.Regulation of neuroblastoma differentiation by forkhead transcription factors FOXO1/3/4 through the receptor tyrosine kinase PDGFRA Identification of functional marker proteins in the mammalian growth cone.Rab5 and Rab4 regulate axon elongation in the Xenopus visual system.Scale Invariant Disordered Nanotopography Promotes Hippocampal Neuron Development and Maturation with Involvement of Mechanotransductive Pathways.Dock protein family in brain development and neurological disease.Galanin stimulates neurite outgrowth from sensory neurons by inhibition of Cdc42 and Rho GTPases and activation of cofilin.Rho-guanine nucleotide exchange factors during development: Force is nothing without control.The role of small GTPases in neuronal morphogenesis and polarity.Molecular symmetry-constrained systematic search approach to structure solution of the coiled-coil SRGAP2 F-BARx domain.Functional investigation of a schizophrenia GWAS signal at the CDC42 gene.Ethanol alters BDNF-induced Rho GTPase activation in axonal growth cones.Enhanced axonal regeneration by transplanted Wnt3a-secreting human mesenchymal stem cells in a rat model of spinal cord injury.Calcium signals and FGF-2 induced neurite growth in cultured parasympathetic neurons: spatial localization and mechanisms of activation.Arhgef1 negatively regulates neurite outgrowth through activation of RhoA signaling pathways.MARCKS regulates neuritogenesis and interacts with a CDC42 signaling network

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Spatial mapping of the neurite and soma proteomes reveals a functional Cdc42/Rac regulatory network

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description

2008 nî lūn-bûn

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2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2008年の論文

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Spatial mapping of the neurite ...... l Cdc42/Rac regulatory network

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Spatial mapping of the neurite ...... l Cdc42/Rac regulatory network

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Spatial mapping of the neurite ...... l Cdc42/Rac regulatory network

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Spatial mapping of the neurite ...... l Cdc42/Rac regulatory network

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Spatial mapping of the neurite ...... l Cdc42/Rac regulatory network

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Proceedings of the National Academy of Sciences of the United States of America

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Spatial mapping of the neurite ...... l Cdc42/Rac regulatory network

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David G Camp

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David J Anderson

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Feng Yang

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Kenneth J Auberry

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Laurie J Gay

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Therese R Clauss

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Wei Wang

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Yingchun Wang

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P2860

The c-Fes tyrosine kinase cooperates with the breakpoint cluster region protein (Bcr) to induce neurite extension in a Rac- and Cdc42-dependent manner

Endocytic protein intersectin-l regulates actin assembly via Cdc42 and N-WASP

Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway

The Human Rho-GEF trio and its target GTPase RhoG are involved in the NGF pathway, leading to neurite outgrowth

Human RhoGAP domain-containing proteins: structure, function and evolutionary relationships

Small GTPase Tc10 and its homologue RhoT induce N-WASP-mediated long process formation and neurite outgrowth

Generation and characterization of Rac3 knockout mice.

Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells.

Rho GTPases and their effector proteins

A network-based analysis of systemic inflammation in humans

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105

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Richard D. Smith

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5607571

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2542865

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