Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis
about
Human SREBP1c expression in liver is directly regulated by peroxisome proliferator-activated receptor alpha (PPARalpha)Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissueEstablishment of a monoclonal antibody for human LXRalpha: Detection of LXRalpha protein expression in human macrophagesTranscriptional regulation of hepatic lipogenesisEnergy metabolism in the liverFasting-induced FGF21 is repressed by LXR activation via recruitment of an HDAC3 corepressor complex in miceTranscriptional control of hepatic lipid metabolism by SREBP and ChREBP.NPC1L1 inhibitor ezetimibe is a reliable therapeutic agent for non-obese patients with nonalcoholic fatty liver disease.LXRβ is required for glucocorticoid-induced hyperglycemia and hepatosteatosis in mice.Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosisDeciphering the nuclear bile acid receptor FXR paradigm.New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c.Effects of adiposity on plasma lipid response to reductions in dietary saturated fatty acids and cholesterol.Insulin regulation of cholesterol 7alpha-hydroxylase expression in human hepatocytes: roles of forkhead box O1 and sterol regulatory element-binding protein 1c.Early growth response 1 (Egr1) regulates cholesterol biosynthetic gene expression.Cholesterol synthesis is associated with hepatic lipid content and dependent on fructose/glucose intake in healthy humansLipoprotein kinetics in the metabolic syndrome: pathophysiological and therapeutic lessons from stable isotope studiesTranscriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR.Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake.Munc18c in adipose tissue is downregulated in obesity and is associated with insulinRole of ChREBP in hepatic steatosis and insulin resistance.Supra-molecular association and polymorphic behaviour in systems containing bile acid salts.Current role of fenofibrate in the prevention and management of non-alcoholic fatty liver diseaseRegulation of hepatic fatty acid elongase and desaturase expression in diabetes and obesity.Liver X receptor α mediates hepatic triglyceride accumulation through upregulation of G0/G1 Switch Gene 2 expression.Insulin signaling in fatty acid and fat synthesis: a transcriptional perspective.Hepatic steatosis in type 1 diabetes.Insulin-Mediated Downregulation of Apolipoprotein A-I Gene in Human Hepatoma Cell Line HepG2: The Role of Interaction Between FOXO1 and LXRβ Transcription Factors.Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity.Liver X receptor α is involved in the transcriptional regulation of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene.Effect of dietary fat on hepatic liver X receptor expression in P-glycoprotein deficient mice: implications for cholesterol metabolism.Nuclear receptor liver X receptor is O-GlcNAc-modified in response to glucose.Fibroblast growth factor-19, a novel factor that inhibits hepatic fatty acid synthesisThe liver X receptor ligand T0901317 down-regulates APOA5 gene expression through activation of SREBP-1c.Jatropha curcas Protein Concentrate Stimulates Insulin Signaling, Lipogenesis, Protein Synthesis and the PKCα Pathway in Rat Liver.Insulin activates the rat sterol-regulatory-element-binding protein 1c (SREBP-1c) promoter through the combinatorial actions of SREBP, LXR, Sp-1 and NF-Y cis-acting elements.Expression of the insulin-responsive glucose transporter GLUT4 in adipocytes is dependent on liver X receptor alpha.Identification of a novel rat hepatic gene induced early by insulin, independently of glucose.Hepatic glucose sensing: does flux matter?Selective proteolytic processing of rat hepatic sterol regulatory element binding protein-1 (SREBP-1) and SREBP-2 during postnatal development.
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P2860
Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis
description
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2002
@ast
im März 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/03/22)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/03/22)
@nl
наукова стаття, опублікована в березні 2002
@uk
name
Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis
@ast
Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis
@en
Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis
@nl
type
label
Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis
@ast
Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis
@en
Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis
@nl
prefLabel
Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis
@ast
Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis
@en
Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis
@nl
P2093
P2860
P356
P1476
Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis
@en
P2093
Gertrud U. Schuster
Hilde Hermansen Steineger
Hilde Irene Nebb
Kari Anne Risan Tobin
Sissel Mahle Andresen
P2860
P304
10691–10697
P356
10.1074/JBC.M109771200
P407
P577
2002-03-22T00:00:00Z