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Interaction of Rac exchange factors Tiam1 and Ras-GRF1 with a scaffold for the p38 mitogen-activated protein kinase cascadeMechanical tension can specify axonal fate in hippocampal neuronsRho GTPases at the crossroad of signaling networks in mammals: impact of Rho-GTPases on microtubule organization and dynamicsRho family GTPases: key players in neuronal development, neuronal survival, and neurodegenerationTiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neuronsTrkB binds and tyrosine-phosphorylates Tiam1, leading to activation of Rac1 and induction of changes in cellular morphologyTiam1 mediates neurite outgrowth induced by ephrin-B1 and EphA2Agrin induced morphological and structural changes in growth cones of cultured hippocampal neuronsLocal phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells.Tiam1 as a signaling mediator of nerve growth factor-dependent neurite outgrowthThe light chain 1 subunit of the microtubule-associated protein 1B (MAP1B) is responsible for Tiam1 binding and Rac1 activation in neuronal cellsThe dynein light chain Tctex-1 has a dynein-independent role in actin remodeling during neurite outgrowthRegulation of spine density and morphology by IQGAP1 protein domainsLIMK1 regulates Golgi dynamics, traffic of Golgi-derived vesicles, and process extension in primary cultured neuronsLis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization.Growth cone-like waves transport actin and promote axonogenesis and neurite branching.Evidence for the involvement of Lfc and Tctex-1 in axon formationGenome-wide methylation analysis of a large population sample shows neurological pathways involvement in chronic widespread musculoskeletal pain.Distinct ligand specificity of the Tiam1 and Tiam2 PDZ domainsDiscovery of long-range inhibitory signaling to ensure single axon formation.Evaluation of candidate genes from orphan FEB and GEFS+ loci by analysis of human brain gene expression atlasesMAP1B regulates axonal development by modulating Rho-GTPase Rac1 activityCell biology in neuroscience: Cellular and molecular mechanisms underlying axon formation, growth, and branching.The ADNP derived peptide, NAP modulates the tubulin pool: implication for neurotrophic and neuroprotective activitiesCalpain activation by Wingless-type murine mammary tumor virus integration site family, member 5A (Wnt5a) promotes axonal growth.Control of synapse development and plasticity by Rho GTPase regulatory proteins.Involvement of SARA in Axon and Dendrite Growth.The Rac activator Tiam1 is required for polarized protrusional outgrowth of primary astrocytes by affecting the organization of the microtubule network.Neuronal polarity: demarcation, growth and commitment.Microtubule stabilization specifies initial neuronal polarization.Regulation of microtubule stability and organization by mammalian Par3 in specifying neuronal polarity.Protein kinase d regulates trafficking of dendritic membrane proteins in developing neurons.Neuronal cell depolarization induces intragenic chromatin modifications affecting NCAM alternative splicing.KIF4 mediates anterograde translocation and positioning of ribosomal constituents to axons.Dosage of amyloid precursor protein affects axonal contact guidance in Down syndrome.A gene trap knockout of the Tiam-1 protein results in malformation of the early embryonic brain.Establishment of axon-dendrite polarity in developing neurons.Neuronal Rho GEFs in synaptic physiology and behavior.Par proteins and neuronal polarity.Rho-guanine nucleotide exchange factors during development: Force is nothing without control.
P2860
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P2860
description
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
@ast
im April 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/04/01)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/04/01)
@nl
наукова стаття, опублікована у квітні 2001
@uk
مقالة علمية (نشرت في أبريل 2001)
@ar
name
Evidence for the involvement of Tiam1 in axon formation
@ast
Evidence for the involvement of Tiam1 in axon formation
@en
Evidence for the involvement of Tiam1 in axon formation
@nl
type
label
Evidence for the involvement of Tiam1 in axon formation
@ast
Evidence for the involvement of Tiam1 in axon formation
@en
Evidence for the involvement of Tiam1 in axon formation
@nl
prefLabel
Evidence for the involvement of Tiam1 in axon formation
@ast
Evidence for the involvement of Tiam1 in axon formation
@en
Evidence for the involvement of Tiam1 in axon formation
@nl
P2093
P1476
Evidence for the involvement of Tiam1 in axon formation
@en
P2093
P304
P356
10.1523/JNEUROSCI.21-07-02361.2001
P407
P577
2001-04-01T00:00:00Z