Interleukin-1 beta-mediated suppression of RXR:RAR transactivation of the Ntcp promoter is JNK-dependent
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Bile acid transportersEndotoxin leads to rapid subcellular re-localization of hepatic RXRalpha: A novel mechanism for reduced hepatic gene expression in inflammationThe role of inflammation in cholestasis: clinical and basic aspectsDegradation of the apical sodium-dependent bile acid transporter by the ubiquitin-proteasome pathway in cholangiocytesDecreased expression levels of rat liver glutathione S-transferase A2 and albumin during the acute phase response are mediated by HNF1 (hepatic nuclear factor 1) and IL6DEX-NPClinical application of transcriptional activators of bile salt transporters.Nuclear receptors: mediators and modifiers of inflammation-induced cholestasis.Role of liver-enriched transcription factors and nuclear receptors in regulating the human, mouse, and rat NTCP gene.The expression of the solute carriers NTCP and OCT-1 is regulated by cholesterol in HepG2 cells.Differential role of Toll-interleukin 1 receptor domain-containing adaptor protein in Toll-like receptor 2-mediated regulation of gene expression of hepatic cytokines and drug-metabolizing enzymes.Bile acids and cytokines inhibit the human cholesterol 7 alpha-hydroxylase gene via the JNK/c-jun pathway in human liver cellsHyperhomocysteinemia decreases circulating high-density lipoprotein by inhibiting apolipoprotein A-I Protein synthesis and enhancing HDL cholesterol clearanceRosiglitazone attenuates suppression of RXRalpha-dependent gene expression in inflamed liver.Elevated copper impairs hepatic nuclear receptor function in Wilson's disease.Role of Adaptor Protein Toll-Like Interleukin Domain Containing Adaptor Inducing Interferon β in Toll-Like Receptor 3- and 4-Mediated Regulation of Hepatic Drug Metabolizing Enzyme and Transporter Genes.Molecular and macromolecular alterations of recombinant adenoviral vectors do not resolve changes in hepatic drug metabolism during infectionMitogenic effect of orphan receptor TR3 and its regulation by MEKK1 in lung cancer cells.Regulation of gene expression of hepatic drug metabolizing enzymes and transporters by the Toll-like receptor 2 ligand, lipoteichoic acid.Curcumin improves sclerosing cholangitis in Mdr2-/- mice by inhibition of cholangiocyte inflammatory response and portal myofibroblast proliferation.Nuclear receptors as therapeutic targets in cholestatic liver diseases.Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease.Role of constitutive androstane receptor in Toll-like receptor-mediated regulation of gene expression of hepatic drug-metabolizing enzymes and transportersRegulation of human hepatic drug transporter expression by pro-inflammatory cytokines.Cytokine signaling modulates blood-brain barrier function.Inhibition of JNK signalling mediates PPARα-dependent protection against intrahepatic cholestasis by fenofibrate.Regulation of drug-metabolizing enzymes in infectious and inflammatory disease: implications for biologics-small molecule drug interactions.Phosphorylation of the human retinoid X receptor alpha at serine 260 impairs coactivator(s) recruitment and induces hormone resistance to multiple ligands.JNK- and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells.Nuclear export of retinoid X receptor alpha in response to interleukin-1beta-mediated cell signaling: roles for JNK and SER260.IL-1β-Induced Downregulation of the Multifunctional PDZ Adaptor PDZK1 Is Attenuated by ERK Inhibition, RXRα, or PPARα Stimulation in Enterocytes.Cytokine regulation of human sterol 12alpha-hydroxylase (CYP8B1) gene.Enhanced retinoid-induced apoptosis of MDA-MB-231 breast cancer cells by PKC inhibitors involves activation of ERK.Redundant roles for cJun-N-terminal kinase 1 and 2 in interleukin-1beta-mediated reduction and modification of murine hepatic nuclear retinoid X receptor alpha.Gene-specific alterations of hepatic gene expression by ligand activation or hepatocyte-selective inhibition of retinoid X receptor-α signalling during inflammation.Hepatoprotection in bile duct ligated mice mediated by darbepoetin-α is not caused by changes in hepatobiliary transporter expression.The CCT promoter directs high-level transgene expression in distal lung epithelial cell lines.Constitutive secretion of serum albumin requires reversible protein tyrosine phosphorylation events in trans-Golgi.Cytokine-dependent regulation of hepatic organic anion transporter gene transactivators in mouse liver.Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver.Degradation of the sodium taurocholate cotransporting polypeptide (NTCP) by the ubiquitin-proteasome system.
P2860
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P2860
Interleukin-1 beta-mediated suppression of RXR:RAR transactivation of the Ntcp promoter is JNK-dependent
description
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2002
@ast
im August 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/08/30)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/08/30)
@nl
наукова стаття, опублікована в серпні 2002
@uk
name
Interleukin-1 beta-mediated su ...... Ntcp promoter is JNK-dependent
@ast
Interleukin-1 beta-mediated su ...... Ntcp promoter is JNK-dependent
@en
Interleukin-1 beta-mediated su ...... Ntcp promoter is JNK-dependent
@nl
type
label
Interleukin-1 beta-mediated su ...... Ntcp promoter is JNK-dependent
@ast
Interleukin-1 beta-mediated su ...... Ntcp promoter is JNK-dependent
@en
Interleukin-1 beta-mediated su ...... Ntcp promoter is JNK-dependent
@nl
prefLabel
Interleukin-1 beta-mediated su ...... Ntcp promoter is JNK-dependent
@ast
Interleukin-1 beta-mediated su ...... Ntcp promoter is JNK-dependent
@en
Interleukin-1 beta-mediated su ...... Ntcp promoter is JNK-dependent
@nl
P2093
P2860
P356
P1476
Interleukin-1 beta-mediated su ...... Ntcp promoter is JNK-dependent
@en
P2093
Ho-Young Lee
Jonathan M. Kurie
Saul J. Karpen
Sundararajah Thevananther
Tracy L. Zimmerman
P2860
P304
31416–31422
P356
10.1074/JBC.M204818200
P407
P577
2002-08-30T00:00:00Z