Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak
about
Inhibition of ADP/ATP exchange in receptor-interacting protein-mediated necrosis.Kinetic mechanism of AKT/PKB enzyme familyHexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channelsThe insulin-like growth factor-I-mTOR signaling pathway induces the mitochondrial pyrimidine nucleotide carrier to promote cell growthFas-mediated apoptosis is regulated by the extracellular matrix protein CCN1 (CYR61) in vitro and in vivoHexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondriaGLO1 overexpression in human malignant melanomaHexokinase II detachment from the mitochondria potentiates cisplatin induced cytotoxicity through a caspase-2 dependent mechanismHexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapyTargeting Cancer Metabolism - Revisiting the Warburg EffectsThe mTOR pathway and integrating immune regulationThe role of VDAC in cell death: friend or foe?Heterogeneity of glycolysis in cancers and therapeutic opportunities.Adipose tissue dysfunction and its effects on tumor metabolismMitochondrial tumour suppressors: a genetic and biochemical updateAmyloid-β triggers the release of neuronal hexokinase 1 from mitochondriaDynamic Metabolism in Immune ResponseClotrimazole preferentially inhibits human breast cancer cell proliferation, viability and glycolysisRegulation and cytoprotective role of hexokinase IIICardiac-specific hexokinase 2 overexpression attenuates hypertrophy by increasing pentose phosphate pathway fluxHexokinase II knockdown results in exaggerated cardiac hypertrophy via increased ROS productionMitochondrial adenine nucleotide transport and cardioprotectionAkt1 governs breast cancer progression in vivo.Matrine Suppresses the ER-positive MCF Cells by Regulating Energy Metabolism and Endoplasmic Reticulum Stress Signaling Pathway.Hexokinase II-derived cell-penetrating peptide targets mitochondria and triggers apoptosis in cancer cellsmiR-17/20 sensitization of breast cancer cells to chemotherapy-induced apoptosis requires Akt1.Is Akt the "Warburg kinase"?-Akt-energy metabolism interactions and oncogenesis.Voltage dependent anion channel-1 regulates death receptor mediated apoptosis by enabling cleavage of caspase-8.Mitochondrial and postmitochondrial survival signaling in cancer.Targeting hexokinase 2 inhibition promotes radiosensitization in HPV16 E7-induced cervical cancer and suppresses tumor growth.Akt and c-Myc differentially activate cellular metabolic programs and prime cells to bioenergetic inhibition.Proteomic analysis of extracellular ATP-regulated proteins identifies ATP synthase beta-subunit as a novel plant cell death regulator.Deguelin inhibits non-small cell lung cancer via down-regulating Hexokinases II-mediated glycolysis.Mitochondrial integrity: preservation through Akt/Pim-1 kinase signaling in the cardiomyocyteGene expression meta-analysis identifies VDAC1 as a predictor of poor outcome in early stage non-small cell lung cancer.Two novel types of hexokinases in the moss Physcomitrella patensBuilding a human kinase gene repository: bioinformatics, molecular cloning, and functional validationMitochondrial VDAC1: A Key Gatekeeper as Potential Therapeutic TargetAkt2 modulates glucose availability and downstream apoptotic pathways during development.Thyroid states regulate subcellular glucose phosphorylation activity in male mice.
P2860
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P2860
Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak
description
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Dezember 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/12/03)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/12/03)
@nl
наукова стаття, опублікована в грудні 2004
@uk
مقالة علمية (نشرت في 3-12-2004)
@ar
name
Hexokinase-mitochondria intera ...... ence or absence of Bax and Bak
@ast
Hexokinase-mitochondria intera ...... ence or absence of Bax and Bak
@en
Hexokinase-mitochondria intera ...... ence or absence of Bax and Bak
@nl
type
label
Hexokinase-mitochondria intera ...... ence or absence of Bax and Bak
@ast
Hexokinase-mitochondria intera ...... ence or absence of Bax and Bak
@en
Hexokinase-mitochondria intera ...... ence or absence of Bax and Bak
@nl
prefLabel
Hexokinase-mitochondria intera ...... ence or absence of Bax and Bak
@ast
Hexokinase-mitochondria intera ...... ence or absence of Bax and Bak
@en
Hexokinase-mitochondria intera ...... ence or absence of Bax and Bak
@nl
P2093
P3181
P1433
P1476
Hexokinase-mitochondria intera ...... ence or absence of Bax and Bak
@en
P2093
Craig B. Thompson
Jennifer E. Skeen
Kathrin Gottlob
Nathan Majewski
Navdeep S. Chandel
Nissim Hay
Platina E. Coy
Prashanth Bhaskar
Veronique Nogueira
P304
P3181
P356
10.1016/J.MOLCEL.2004.11.014
P577
2004-12-03T00:00:00Z