Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1
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The neurology of mTORTherapeutic targeting of cellular metabolism in cells with hyperactive mTORC1: a paradigm shiftCerebellar Development and Autism Spectrum Disorder in Tuberous Sclerosis Complex.Oxidative Stress Challenge Uncovers Trichloroacetaldehyde Hydrate-Induced Mitoplasticity in Autistic and Control Lymphoblastoid Cell Lines.Genetic activation of mTORC1 signaling worsens neurocognitive outcome after traumatic brain injury.Activity-dependent neuroprotective protein (ADNP) exhibits striking sexual dichotomy impacting on autistic and Alzheimer's pathologies.Tuberous Sclerosis: A New Frontier in Targeted Treatment of AutismmTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy.Sustained activation of mTORC1 in macrophages increases AMPKα-dependent autophagy to maintain cellular homeostasisDehydroandrographolide, an iNOS inhibitor, extracted from Andrographis paniculata (Burm.f.) Nees, induces autophagy in human oral cancer cells.Evidence Supporting a Lymphatic Endothelium Origin for Angiomyolipoma, a TSC2(-) Tumor Related to Lymphangioleiomyomatosis.Regulation of PERK-eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytesmTOR, a Potential Target to Treat Autism Spectrum Disorder.Impaired Mitochondrial Dynamics and Mitophagy in Neuronal Models of Tuberous Sclerosis Complex.TSC but not PTEN loss in starving cones of retinitis pigmentosa mice leads to an autophagy defect and mTORC1 dissociation from the lysosome.Dysfunctional mTORC1 Signaling: A Convergent Mechanism between Syndromic and Nonsyndromic Forms of Autism Spectrum Disorder?Autophagy in neuronal cells: general principles and physiological and pathological functions.Pimozide reduces toxic forms of tau in TauC3 mice via 5' adenosine monophosphate-activated protein kinase-mediated autophagy.Congenital disorders of autophagy: an emerging novel class of inborn errors of neuro-metabolism.Endosomal system genetics and autism spectrum disorders: A literature review.Hydrogen sulfide reduces serum triglyceride by activating liver autophagy via the AMPK-mTOR pathway.Modulation of Autophagy by Calcium Signalosome in Human Disease.Coordinated activation of AMP-activated protein kinase, extracellular signal-regulated kinase, and autophagy regulates phorbol myristate acetate-induced differentiation of SH-SY5Y neuroblastoma cells.Neurodegeneration in ataxia-telangiectasia: Multiple roles of ATM kinase in cellular homeostasis.Hypothalamic AMPK-induced autophagy increases food intake by regulating NPY and POMC expression.TCS2 Increases Olaquindox-Induced Apoptosis by Upregulation of ROS Production and Downregulation of Autophagy in HEK293 Cells.Purkinje cells derived from TSC patients display hypoexcitability and synaptic deficits associated with reduced FMRP levels and reversed by rapamycin.LicA induces autophagy through ULK1/Atg13 and ROS pathway in human hepatocellular carcinoma cells.Inhibition of p70 S6 kinase activity by A77 1726 induces autophagy and enhances the degradation of superoxide dismutase 1 (SOD1) protein aggregates.Role of mTOR Complexes in Neurogenesis.
P2860
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P2860
Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1
description
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2014
@ast
im Juli 2014 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2014/07/15)
@sk
vědecký článek publikovaný v roce 2014
@cs
wetenschappelijk artikel (gepubliceerd op 2014/07/15)
@nl
наукова стаття, опублікована в липні 2014
@uk
مقالة علمية (نشرت في 15-7-2014)
@ar
name
Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1
@ast
Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1
@en
Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1
@nl
type
label
Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1
@ast
Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1
@en
Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1
@nl
prefLabel
Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1
@ast
Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1
@en
Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1
@nl
P2093
P2860
P50
P3181
P356
P1476
Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1
@en
P2093
Alessia Di Nardo
David J Kwiatkowski
Delia M Talos
Emily Greene-Colozzi
Erica Kwiatkowski
Jarrett D Leech
Mary H Wertz
Pelin Dilsiz
Peter T Tsai
P2860
P304
P3181
P356
10.1093/HMG/DDU101
P577
2014-03-05T00:00:00Z