Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks - Test2 - elhamkhani - TriplyDB

Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks

Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks

http://www.wikidata.org/entity/Q24612235

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Context-Dependent Regulation of Autophagy by IKK-NF-κB Signaling: Impact on the Aging Process ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells Sickness-Associated Anorexia: Mother Nature's Idea of Immunonutrition?Oncosuppressive functions of decorin New Potential Pharmacological Functions of Chinese Herbal Medicines via Regulation of Autophagy STING: infection, inflammation and cancer Inflammation and intracellular metabolism: new targets in OA Cell Death Conversion under Hypoxic Condition in Tumor Development and Therapy Autophagy signal transduction by ATG proteins: from hierarchies to networks Mitochondria-Associated Endoplasmic Reticulum Membranes Microenvironment: Targeting Autophagic and Apoptotic Pathways in Cancer Therapy Hepatitis C virus comes for dinner: How the hepatitis C virus interferes with autophagy Decoding the Matrix: Instructive Roles of Proteoglycan Receptors Regulation of adipocyte autophagy--the potential anti-obesity mechanism of high density lipoprotein and ApolipoproteinA-I Mitophagy in hematopoietic stem cells: the case for exploration You eat what you are: autophagy inhibition as a therapeutic strategy in leukemia Autophagy modulation as a potential therapeutic target for diverse diseases After the banquet: mitochondrial biogenesis, mitophagy, and cell survival Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy Transcriptional and epigenetic regulation of autophagy in aging Role of the inositol 1,4,5-trisphosphate receptor/Ca2+-release channel in autophagy Huntingtin functions as a scaffold for selective macroautophagy The hallmarks of aging Teaching the basics of autophagy and mitophagy to redox biologists--mechanisms and experimental approaches Autophagy induction is a Tor- and Tp53-independent cell survival response in a zebrafish model of disrupted ribosome biogenesis Stimulation of autophagy improves endoplasmic reticulum stress-induced diabetes Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy Inhibition of mTOR-dependent autophagy sensitizes leukemic cells to cytarabine-induced apoptotic death Autophagy activation is involved in 3,4-methylenedioxymethamphetamine ('ecstasy')--induced neurotoxicity in cultured cortical neurons AMDE-1 is a dual function chemical for autophagy activation and inhibition Impacts of autophagy-inducing ingredient of areca nut on tumor cells G9a Inhibition Induces Autophagic Cell Death via AMPK/mTOR Pathway in Bladder Transitional Cell Carcinoma Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1 Boning up on autophagy: the role of autophagy in skeletal biology mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1 Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator Regulation of Beclin 1 Protein Phosphorylation and Autophagy by Protein Phosphatase 2A (PP2A) and Death-associated Protein Kinase 3 (DAPK3).Regulation of ion channels and transporters by AMP-activated kinase (AMPK).Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells.How to explain exercise-induced phenotype from molecular data: rethink and reconstruction based on AMPK and mTOR signaling.

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Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks

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2012 nî lūn-bûn

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2012 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2012年の論文

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Antje S Löffler

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Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

Structure of mammalian AMPK and its regulation by ADP

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

Ambra1 regulates autophagy and development of the nervous system

Atg101, a novel mammalian autophagy protein interacting with Atg13

siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy

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2-11

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204098

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10.1128/MCB.06159-11

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1

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32

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Sebastian Alers

Sebastian Wesselborg

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2012-01-01T00:00:00Z

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22025673

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3255710

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