Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions
about
The deubiquitinating enzyme CYLD controls apical docking of basal bodies in ciliated epithelial cellsThe business of deubiquitination - location, location, locationProtein homeostasis at the plasma membraneLa FAM fatale: USP9X in development and diseaseUSP9X regulates centrosome duplication and promotes breast carcinogenesis.The USP21 short variant (USP21SV) lacking NES, located mostly in the nucleus in vivo, activates transcription by deubiquitylating ubH2A in vitro.Regulation of neuronal morphogenesis and positioning by ubiquitin-specific proteases in the cerebellum.Ubiquitin specific protease 21 is dispensable for normal development, hematopoiesis and lymphocyte differentiationReversible inactivation of deubiquitinases by reactive oxygen species in vitro and in cells.The deubiquitylase USP15 stabilizes newly synthesized REST and rescues its expression at mitotic exitThe Endosome-associated Deubiquitinating Enzyme USP8 Regulates BACE1 Enzyme Ubiquitination and Degradation.The deubiquitinase USP21 maintains the stemness of mouse embryonic stem cells via stabilization of Nanog.USP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase.Microtubule affinity-regulating kinase 4: structure, function, and regulation.Regulation of proteolysis by human deubiquitinating enzymes.Deubiquitylases from genes to organism.Mechanisms of regulation and diversification of deubiquitylating enzyme function.The X-linked deubiquitinase USP9X is an integral component of centrosome.STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling.Monitoring Target Engagement of Deubiquitylating Enzymes Using Activity Probes: Past, Present, and Future.USP30 deubiquitylates mitochondrial Parkin substrates and restricts apoptotic cell death.Integration of cellular ubiquitin and membrane traffic systems: focus on deubiquitylases.p38 inhibition provides anti-DNA virus immunity by regulation of USP21 phosphorylation and STING activation.Proteostasis, oxidative stress and aging.Structure-function analysis of USP1: insights into the role of Ser313 phosphorylation site and the effect of cancer-associated mutations on autocleavage.USP21 regulates Hippo pathway activity by mediating MARK protein turnover.The centrosomal deubiquitylase USP21 regulates Gli1 transcriptional activity and stability.Structural basis for recruiting and shuttling of the spliceosomal deubiquitinase USP4 by SART3.Regulation of the cell cycle and centrosome biology by deubiquitylases.Mechanism and regulation of the Lys6-selective deubiquitinase USP30.The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity.Otud7a Knockout Mice Recapitulate Many Neurological Features of 15q13.3 Microdeletion Syndrome.USP8 controls the trafficking and sorting of lysosomal enzymes.Dual role of USP30 in controlling basal pexophagy and mitophagy.
P2860
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P2860
Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions
description
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2012
@ast
im März 2012 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2012/03/01)
@sk
vědecký článek publikovaný v roce 2012
@cs
wetenschappelijk artikel (gepubliceerd op 2012/03/01)
@nl
наукова стаття, опублікована в березні 2012
@uk
مقالة علمية (نشرت في مارس 2012)
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name
Systematic survey of deubiquit ...... crotubule-associated functions
@ast
Systematic survey of deubiquit ...... crotubule-associated functions
@en
Systematic survey of deubiquit ...... crotubule-associated functions
@nl
type
label
Systematic survey of deubiquit ...... crotubule-associated functions
@ast
Systematic survey of deubiquit ...... crotubule-associated functions
@en
Systematic survey of deubiquit ...... crotubule-associated functions
@nl
prefLabel
Systematic survey of deubiquit ...... crotubule-associated functions
@ast
Systematic survey of deubiquit ...... crotubule-associated functions
@en
Systematic survey of deubiquit ...... crotubule-associated functions
@nl
P2093
P2860
P3181
P356
P1476
Systematic survey of deubiquit ...... crotubule-associated functions
@en
P2093
Claire Heride
Daniel J. Rigden
Michael J. Clague
Sebastian D. Hayes
P2860
P304
P3181
P356
10.1091/MBC.E11-08-0668
P577
2012-03-01T00:00:00Z