Identification of a novel isopeptidase with dual specificity for ubiquitin- and NEDD8-conjugated proteins
about
The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondriaStructural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1.The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8pOptimising methods for the preservation, capture and identification of ubiquitin chains and ubiquitylated proteins by immunoblottingInhibition of NEDD8-conjugation pathway by novel molecules: potential approaches to anticancer therapyPolyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21Targeting of NEDD8 and its conjugates for proteasomal degradation by NUB1PIAS1-mediated sumoylation of focal adhesion kinase activates its autophosphorylationIdentification and characterization of DEN1, a deneddylase of the ULP familyProgressive Hearing Loss in Mice Carrying a Mutation in Usp53.Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functionsTbata modulates thymic stromal cell proliferation and thymus functionDeubiquitylation of histone H2A activates transcriptional initiation via trans-histone cross-talk with H3K4 di- and trimethylationRegulation of the NEDD8 conjugation system by a splicing variant, NUB1L.echinus, required for interommatidial cell sorting and cell death in the Drosophila pupal retina, encodes a protein with homology to ubiquitin-specific proteases.Ubiquitin-specific peptidase 21 inhibits tumor necrosis factor alpha-induced nuclear factor kappaB activation via binding to and deubiquitinating receptor-interacting protein 1.The molecular determinants for distinguishing between ubiquitin and NEDD8 by USP2.NUB1, a NEDD8-interacting protein, is induced by interferon and down-regulates the NEDD8 expression.Mechanism of processing of the NF-kappa B2 p100 precursor: identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCF(beta-TrCP) ubiquitin ligase.Nedd8 on cullin: building an expressway to protein destruction.The molecular determinants of NEDD8 specific recognition by human SENP8.SUMO: of branched proteins and nuclear bodies.Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteins.Targeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapyCaspase-1 promotes Epstein-Barr virus replication by targeting the large tegument protein deneddylase to the nucleus of productively infected cells.Two closely related ubiquitin C-terminal hydrolase isozymes function as reciprocal modulators of germ cell apoptosis in cryptorchid testis.Ubiquitin specific protease 21 is dispensable for normal development, hematopoiesis and lymphocyte differentiationCalorie-related rapid onset of alveolar loss, regeneration, and changes in mouse lung gene expression.Function and regulation of protein neddylation. 'Protein modifications: beyond the usual suspects' review seriesNEDD8 ultimate buster-1 long (NUB1L) protein promotes transfer of NEDD8 to proteasome for degradation through the P97UFD1/NPL4 complex.Expression of neddylation-related proteins in melanoma cell lines and the effect of neddylation on melanoma proliferation.Ubiquitination of E3 ubiquitin ligase TRIM5 alpha and its potential role.Degradation of wild-type vasopressin precursor and pathogenic mutants by the proteasome.A general chemical ligation approach towards isopeptide-linked ubiquitin and ubiquitin-like assay reagents.The NEDD8 pathway is essential for SCF(beta -TrCP)-mediated ubiquitination and processing of the NF-kappa B precursor p105.sNASP inhibits TLR signaling to regulate immune response in sepsis.Apicomplexan UCHL3 retains dual specificity for ubiquitin and Nedd8 throughout evolution
P2860
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P2860
Identification of a novel isopeptidase with dual specificity for ubiquitin- and NEDD8-conjugated proteins
description
2000 nî lūn-bûn
@nan
2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Identification of a novel isop ...... and NEDD8-conjugated proteins
@ast
Identification of a novel isop ...... and NEDD8-conjugated proteins
@en
Identification of a novel isop ...... and NEDD8-conjugated proteins
@en-gb
Identification of a novel isop ...... and NEDD8-conjugated proteins
@nl
type
label
Identification of a novel isop ...... and NEDD8-conjugated proteins
@ast
Identification of a novel isop ...... and NEDD8-conjugated proteins
@en
Identification of a novel isop ...... and NEDD8-conjugated proteins
@en-gb
Identification of a novel isop ...... and NEDD8-conjugated proteins
@nl
prefLabel
Identification of a novel isop ...... and NEDD8-conjugated proteins
@ast
Identification of a novel isop ...... and NEDD8-conjugated proteins
@en
Identification of a novel isop ...... and NEDD8-conjugated proteins
@en-gb
Identification of a novel isop ...... and NEDD8-conjugated proteins
@nl
P2093
P2860
P356
P1476
Identification of a novel isop ...... and NEDD8-conjugated proteins
@en
P2093
P2860
P304
P356
10.1074/JBC.275.19.14212
P407
P577
2000-05-12T00:00:00Z