Focal adhesion kinase (FAK)-dependent regulation of S-phase kinase-associated protein-2 (Skp-2) stability. A novel mechanism regulating smooth muscle cell proliferation
about
Growth control by intracellular tension and extracellular stiffnessMutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27Kip1 in human melanoma cellsTranscriptional regulation of S phase kinase-associated protein 2 by NR4A orphan nuclear receptor NOR1 in vascular smooth muscle cellsAdhesion-dependent Skp2 transcription requires selenocysteine tRNA gene transcription-activating factor (STAF)S-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivoHaploinsufficiency of the maspin tumor suppressor gene leads to hyperplastic lesions in prostateRole of smooth muscle cells in the initiation and early progression of atherosclerosis.Focal adhesion kinase controls cellular levels of p27/Kip1 and p21/Cip1 through Skp2-dependent and -independent mechanisms.PKA and Epac synergistically inhibit smooth muscle cell proliferation.Phosphorylation of ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) by Akt promotes stability and mitogenic function of S-phase kinase-associated protein-2 (Skp2).AMPKα2 deletion exacerbates neointima formation by upregulating Skp2 in vascular smooth muscle cells.The COP9 signalosome and vascular function: intriguing possibilities?Focal adhesion kinase is a phospho-regulated repressor of Rac and proliferation in human endothelial cells.Role of UDP-N-acetylglucosamine (GlcNAc) and O-GlcNAcylation of hyaluronan synthase 2 in the control of chondroitin sulfate and hyaluronan synthesis.Berberine cooperates with adrenal androgen dehydroepiandrosterone sulfate to attenuate PDGF-induced proliferation of vascular smooth muscle cell A7r5 through Skp2 signaling pathway.Acute inhibition of superoxide formation and Rac1 activation by nitric oxide and iloprost in human vascular smooth muscle cells in response to the thromboxane A2 analogue, U46619.Superoxide from NADPH oxidase upregulates type 5 phosphodiesterase in human vascular smooth muscle cells: inhibition with iloprost and NONOate.Rho GTPase, Rac1, regulates Skp2 levels, vascular smooth muscle cell proliferation, and intima formation in vitro and in vivo.
P2860
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P2860
Focal adhesion kinase (FAK)-dependent regulation of S-phase kinase-associated protein-2 (Skp-2) stability. A novel mechanism regulating smooth muscle cell proliferation
description
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2004
@ast
im September 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/09/03)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/09/03)
@nl
наукова стаття, опублікована у вересні 2004
@uk
name
Focal adhesion kinase (FAK)-de ...... ooth muscle cell proliferation
@ast
Focal adhesion kinase (FAK)-de ...... ooth muscle cell proliferation
@en
Focal adhesion kinase (FAK)-de ...... ooth muscle cell proliferation
@nl
type
label
Focal adhesion kinase (FAK)-de ...... ooth muscle cell proliferation
@ast
Focal adhesion kinase (FAK)-de ...... ooth muscle cell proliferation
@en
Focal adhesion kinase (FAK)-de ...... ooth muscle cell proliferation
@nl
prefLabel
Focal adhesion kinase (FAK)-de ...... ooth muscle cell proliferation
@ast
Focal adhesion kinase (FAK)-de ...... ooth muscle cell proliferation
@en
Focal adhesion kinase (FAK)-de ...... ooth muscle cell proliferation
@nl
P2093
P2860
P356
P1476
Focal adhesion kinase (FAK)-de ...... ooth muscle cell proliferation
@en
P2093
Andrew C. Newby
Graciela B. Sala-Newby
P2860
P304
37304–37310
P356
10.1074/JBC.M404307200
P407
P577
2004-09-03T00:00:00Z