S-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivo
about
Genetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligasesTranscriptional regulation of S phase kinase-associated protein 2 by NR4A orphan nuclear receptor NOR1 in vascular smooth muscle cellsAdhesion-dependent Skp2 transcription requires selenocysteine tRNA gene transcription-activating factor (STAF)MAPK phosphorylation of connexin 43 promotes binding of cyclin E and smooth muscle cell proliferation.miR-221/222 compensates for Skp2-mediated p27 degradation and is a primary target of cell cycle regulation by prostacyclin and cAMPTanshinone IIA inhibits hypoxia-induced pulmonary artery smooth muscle cell proliferation via Akt/Skp2/p27-associated pathway.Probucol suppresses human glioma cell proliferation in vitro via ROS production and LKB1-AMPK activationPKA and Epac synergistically inhibit smooth muscle cell proliferation.cAMP-induced actin cytoskeleton remodelling inhibits MKL1-dependent expression of the chemotactic and pro-proliferative factor, CCN1.Phosphorylation of ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) by Akt promotes stability and mitogenic function of S-phase kinase-associated protein-2 (Skp2).AMPKα2 deletion exacerbates neointima formation by upregulating Skp2 in vascular smooth muscle cells.The scaffolding protein EBP50 promotes vascular smooth muscle cell proliferation and neointima formation by regulating Skp2 and p21(cip1).The COP9 signalosome and vascular function: intriguing possibilities?Adenosine Attenuates Human Coronary Artery Smooth Muscle Cell Proliferation by Inhibiting Multiple Signaling Pathways That Converge on Cyclin D.Relative resistance to Mammalian target of rapamycin inhibition in vascular smooth muscle cells of diabetic donors.Epigallocatechin-3-gallate is a potent phytochemical inhibitor of intimal hyperplasia in the wire-injured carotid artery.Dysregulation of the Mammalian Target of Rapamycin and p27Kip1 Promotes Intimal Hyperplasia in Diabetes MellitusPhysiological and pathological role of the ubiquitin-proteasome system in the vascular smooth muscle cell.Protein kinase A and the exchange protein directly activated by cAMP (Epac) modulate phenotype plasticity in human airway smooth muscle.A receptor-specific function for Notch2 in mediating vascular smooth muscle cell growth arrest through cyclin-dependent kinase inhibitor 1B.
P2860
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P2860
S-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivo
description
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
scientific journal article
@en
vedecký článok (publikovaný 2009/11/01)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/11/01)
@nl
наукова стаття, опублікована в листопаді 2009
@uk
مقالة علمية (نشرت في نوفمبر 2009)
@ar
name
S-phase kinase-associated prot ...... nd neointima formation in vivo
@ast
S-phase kinase-associated prot ...... nd neointima formation in vivo
@en
S-phase kinase-associated prot ...... nd neointima formation in vivo
@nl
type
label
S-phase kinase-associated prot ...... nd neointima formation in vivo
@ast
S-phase kinase-associated prot ...... nd neointima formation in vivo
@en
S-phase kinase-associated prot ...... nd neointima formation in vivo
@nl
prefLabel
S-phase kinase-associated prot ...... nd neointima formation in vivo
@ast
S-phase kinase-associated prot ...... nd neointima formation in vivo
@en
S-phase kinase-associated prot ...... nd neointima formation in vivo
@nl
P2093
P2860
P1476
S-phase kinase-associated prot ...... nd neointima formation in vivo
@en
P2093
Andrew C Newby
Graciela B Sala-Newby
Hung-I Yeh
Keiichi I Nakayama
Keiko Nakayama
Kuo-Tung Shu
Yih-Jer Wu
P2860
P304
P356
10.1016/J.JVS.2009.07.066
P50
P577
2009-11-01T00:00:00Z