Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors
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Taking the time to study competitive antagonismStructural Determinants of Agonist Efficacy at the Glutamate Binding Site of N-Methyl-D-Aspartate ReceptorsGlutamate receptor ion channels: structure, regulation, and functionAllosteric modulation of [3H]-CGP39653 binding through the glycine site of the NMDA receptor: further studies in rat and human brainDesensitization of NMDA receptor channels is modulated by glutamate agonists.Influence of a threonine residue in the S2 ligand binding domain in determining agonist potency and deactivation rate of recombinant NR1a/NR2D NMDA receptorsStationary gating of GluN1/GluN2B receptors in intact membrane patchesStaggering of subunits in NMDAR channels.Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids.Agonist-specific gating of NMDA receptors.Characterization of the gating conformational changes in the felbamate binding site in NMDA channelsMutations at F637 in the NMDA receptor NR2A subunit M3 domain influence agonist potency, ion channel gating and alcohol actionElectrogenic glutamate transporters in the CNS: molecular mechanism, pre-steady-state kinetics, and their impact on synaptic signaling.Modulation of NMDA receptor properties and synaptic transmission by the NR3A subunit in mouse hippocampal and cerebrocortical neuronsPharmacological insights obtained from structure-function studies of ionotropic glutamate receptors.Atomistic mechanism for the activation and desensitization of an AMPA-subtype glutamate receptorOlfactory nerve-evoked, metabotropic glutamate receptor-mediated synaptic responses in rat olfactory bulb mitral cells.A family of photoswitchable NMDA receptors.Synthesis and structure activity relationship of tetrahydroisoquinoline-based potentiators of GluN2C and GluN2D containing N-methyl-D-aspartate receptorsD-cycloserine enhances short-delay, but not long-delay, conditioned taste aversion learning in ratsBlockade of hindbrain NMDA receptors containing NR2 subunits increases sucrose intakeInfluence of GluN2 subunit identity on NMDA receptor function.The glutamatergic aspects of schizophrenia molecular pathophysiology: role of the postsynaptic density, and implications for treatmentDistinct functional and pharmacological properties of Triheteromeric GluN1/GluN2A/GluN2B NMDA receptors.Expression and characterization of a glycine-binding fragment of the N-methyl-D-aspartate receptor subunit NR1.AMPA receptors and bacterial periplasmic amino acid-binding proteins share the ionic mechanism of ligand recognition.Novel glycine-dependent inactivation of NMDA receptors in cultured hippocampal neurons.Cloning and Phylogenetic Analysis of NMDA Receptor Subunits NR1, NR2A and NR2B in Xenopus laevis Tadpoles.Single-channel analysis of an NMDA receptor possessing a mutation in the region of the glutamate binding site.Maximum likelihood fitting of single channel NMDA activity with a mechanism composed of independent dimers of subunits.Single-channel analysis of a point mutation of a conserved serine residue in the S2 ligand-binding domain of the NR2A NMDA receptor subunit.A Microfluidic Platform for the Characterisation of CNS Active Compounds.Mg2+ and memantine block of rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes.Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes.
P2860
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P2860
Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
name
Identification of amino acid r ...... binant NR1/NR2A NMDA receptors
@ast
Identification of amino acid r ...... binant NR1/NR2A NMDA receptors
@en
Identification of amino acid r ...... binant NR1/NR2A NMDA receptors
@nl
type
label
Identification of amino acid r ...... binant NR1/NR2A NMDA receptors
@ast
Identification of amino acid r ...... binant NR1/NR2A NMDA receptors
@en
Identification of amino acid r ...... binant NR1/NR2A NMDA receptors
@nl
prefLabel
Identification of amino acid r ...... binant NR1/NR2A NMDA receptors
@ast
Identification of amino acid r ...... binant NR1/NR2A NMDA receptors
@en
Identification of amino acid r ...... binant NR1/NR2A NMDA receptors
@nl
P2093
P1476
Identification of amino acid r ...... binant NR1/NR2A NMDA receptors
@en
P2093
D Colquhoun
R Schoepfer
P304
P356
10.1523/JNEUROSCI.18-02-00581.1998
P407
P577
1998-01-01T00:00:00Z