Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids.
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Neurosteroids: endogenous role in the human brain and therapeutic potentialsNeurosteroid regulation of central nervous system developmentFunctional insights from glutamate receptor ion channel structuresNMDA receptor modulators: an updated patent review (2013-2014)Glutamate receptor ion channels: structure, regulation, and functionSpinal translocator protein (TSPO) modulates pain behavior in rats with CFA-induced monoarthritisThe Major Brain Cholesterol Metabolite 24(S)-Hydroxycholesterol Is a Potent Allosteric Modulator of N-Methyl-D-Aspartate ReceptorsSpatial and temporal boundaries of NMDA receptor hypofunction leading to schizophrenia.Characterization of the convulsant action of pregnenolone sulfateThe Concise Guide to PHARMACOLOGY 2013/14: ligand-gated ion channels.Progesterone protects normative anxiety-like responding among ovariectomized female mice that conditionally express the HIV-1 regulatory protein, Tat, in the CNS.Membrane androgen receptors may mediate androgen reinforcement.Neurosteroids and epilepsy.A role for picomolar concentrations of pregnenolone sulfate in synaptic activity-dependent Ca2+ signaling and CREB activationA steroid modulatory domain on NR2B controls N-methyl-D-aspartate receptor proton sensitivityStructural determinants and mechanism of action of a GluN2C-selective NMDA receptor positive allosteric modulator.Pregnenolone sulfate: from steroid metabolite to TRP channel ligand.Pregnenolone sulfate and its enantiomer: differential modulation of memory in a spatial discrimination task using forebrain NMDA receptor deficient miceNeurosteroid biosynthesis downregulation and changes in GABAA receptor subunit composition: A biomarker axis in stress-induced cognitive and emotional impairment.Ethanol exposure in early adolescence inhibits intrinsic neuronal plasticity via sigma-1 receptor activation in hippocampal CA1 neurons.Pregnanolone sulfate promotes desensitization of activated NMDA receptors.New advances in NMDA receptor pharmacology.Differential regulation of ionotropic glutamate receptors.Block of NMDA receptor channels by endogenous neurosteroids: implications for the agonist induced conformational states of the channel vestibule.A steroid modulatory domain in NR2A collaborates with NR1 exon-5 to control NMDAR modulation by pregnenolone sulfate and protonsBidirectional Effect of Pregnenolone Sulfate on GluN1/GluN2A N-Methyl-D-Aspartate Receptor Gating Depending on Extracellular Calcium and Intracellular MilieuPregnenolone sulfate as a modulator of synaptic plasticity.Noncompetitive, voltage-dependent NMDA receptor antagonism by hydrophobic anionsNeurosteroids, stress and depression: potential therapeutic opportunities.Adolescents and androgens, receptors and rewards.Effects of neurosteroid actions at N-methyl-D-aspartate and GABA A receptors in the midbrain ventral tegmental area for anxiety-like and mating behavior of female rats.The neuroactive steroid pregnenolone sulfate stimulates trafficking of functional N-methyl D-aspartate receptors to the cell surface via a noncanonical, G protein, and Ca2+-dependent mechanism.Allosteric modulators of NR2B-containing NMDA receptors: molecular mechanisms and therapeutic potentialPharmacological modulation of NMDA receptor activity and the advent of negative and positive allosteric modulatorsProgesterone and its metabolites as therapeutic targets in psychiatric disorders.Calcium-engaged Mechanisms of Nongenomic Action of Neurosteroids.Nanomolar concentrations of pregnenolone sulfate enhance striatal dopamine overflow in vivoThe distribution of placental oxidoreductase isoforms provides different milieus of steroids influencing pregnancy in the maternal and fetal compartment.A NMDA-receptor calcium influx assay sensitive to stimulation by glutamate and glycine/D-serine.Pregnenolone sulfate induces NMDA receptor dependent release of dopamine from synaptic terminals in the striatum
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P2860
Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids.
description
2002 nî lūn-bûn
@nan
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Inhibition of the NMDA respons ...... ceptors by sulphated steroids.
@en
type
label
Inhibition of the NMDA respons ...... ceptors by sulphated steroids.
@en
prefLabel
Inhibition of the NMDA respons ...... ceptors by sulphated steroids.
@en
P2860
P356
P1476
Inhibition of the NMDA respons ...... ceptors by sulphated steroids.
@en
P2093
Andrew Malayev
P2860
P304
P356
10.1038/SJ.BJP.0704543
P407
P577
2002-02-01T00:00:00Z