TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis - Test2 - elhamkhani - TriplyDB

TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis

TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis

http://www.wikidata.org/entity/Q28583900

about

Protein prenylation and synaptic plasticity: implications for Alzheimer's disease Mice deficient in brain-derived neurotrophic factor have altered development of gastric vagal sensory innervation Isoprenoids, small GTPases and Alzheimer's disease.Brain-derived neurotrophic factor and the development of structural neuronal connectivity.Geranylgeranyltransferase I is essential for dendritic development of cerebellar Purkinje cells.Splice variants of SmgGDS control small GTPase prenylation and membrane localization An adenosine-mediated signaling pathway suppresses prenylation of the GTPase Rap1B and promotes cell scattering.NEDD4-1 regulates migration and invasion of glioma cells through CNrasGEF ubiquitination in vitro.Aberrant differentiation of fibroblast progenitors contributes to fibrosis in the aged murine heart: role of elevated circulating insulin levels.Maturation and integration of adult born hippocampal neurons: signal convergence onto small Rho GTPases.Neuronal cholesterol metabolism increases dendritic outgrowth and synaptic markers via a concerted action of GGTase-I and Trk.Regulation of protein prenyltransferase in central neurons.Impaired geranylgeranyltransferase-I regulation reduces membrane-associated Rho protein levels in aged mouse brain.Synapse formation and remodeling.Physical exercise alleviates debilities of normal aging and Alzheimer's disease.Influence of physical exercise on traumatic brain injury deficits: scaffolding effect.The Role of Geranylgeranyltransferase I-Mediated Protein Prenylation in the Brain.Geranylgeranyltransferase I regulates HIF-1α promoting glioblastoma cell migration and invasion.Geranylgeranyltransferase I promotes human glioma cell growth through Rac1 membrane association and activation.Ethanol alters BDNF-induced Rho GTPase activation in axonal growth cones.Geranylgeranyltransferase I mediates BDNF-induced synaptogenesis.Inhibiting geranylgeranyltransferase I activity decreases spine density in central nervous system.Systemic or Forebrain Neuron-Specific Deficiency of Geranylgeranyltransferase-1 Impairs Synaptic Plasticity and Reduces Dendritic Spine Density.Isoprenoids and protein prenylation: implications in the pathogenesis and therapeutic intervention of Alzheimer's disease.

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P2860

TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis

http://www.wikidata.org/entity/Q28583900

description

2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

article publié dans les Procee ...... f the United States of America

@fr

artículu científicu espublizáu en 2008

@ast

im November 2008 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 2008/11/04)

@sk

vědecký článek publikovaný v roce 2008

@cs

wetenschappelijk artikel (gepubliceerd op 2008/11/04)

@nl

наукова стаття, опублікована в листопаді 2008

@uk

name

TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis

@ast

TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis

@en

TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis

@nl

type

label

TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis

@ast

TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis

@en

TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis

@nl

prefLabel

TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis

@ast

TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis

@en

TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis

@nl

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PNAS.0800846105

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Proceedings of the National Academy of Sciences of the United States of America

P1476

TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis

@en

P2093

Bin Liang

http://www.w3.org/2001/XMLSchema#string

Kong-Yan Wu

http://www.w3.org/2001/XMLSchema#string

Xiu-Ping Zhou

http://www.w3.org/2001/XMLSchema#string

Xiu-Qing Fu

http://www.w3.org/2001/XMLSchema#string

Zhen-Ge Luo

http://www.w3.org/2001/XMLSchema#string

P2860

Rho GTPases and the actin cytoskeleton

The Rac1-GEF Tiam1 couples the NMDA receptor to the activity-dependent development of dendritic arbors and spines

The Human Rho-GEF trio and its target GTPase RhoG are involved in the NGF pathway, leading to neurite outgrowth

Mutational analysis of alpha-subunit of protein farnesyltransferase. Evidence for a catalytic role

Distribution of prenyltransferases in rat tissues. Evidence for a cytosolic all-trans-geranylgeranyl diphosphate synthase

All ras proteins are polyisoprenylated but only some are palmitoylated

TrkB binds and tyrosine-phosphorylates Tiam1, leading to activation of Rac1 and induction of changes in cellular morphology

Implication of geranylgeranyltransferase I in synapse formation

Brain-derived neurotrophic factor is required for the maintenance of cortical dendrites

Experience-dependent coincident expression of the effector immediate-early genes arc and Homer 1a in hippocampal and neocortical neuronal networks

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10.1073/PNAS.0800846105

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105

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