Foxl2 disruption causes mouse ovarian failure by pervasive blockage of follicle development
about
A new model of development of the mammalian ovary and folliclesTranscription factor FIGLA is mutated in patients with premature ovarian failureMale sex determination: insights into molecular mechanismsContemporary genetic technologies and female reproductionFoxL2 and Smad3 coordinately regulate follistatin gene transcriptionGenetics of the ovarian reserveHow to make a gonad: cellular mechanisms governing formation of the testes and ovariesMolecular players involved in temperature-dependent sex determination and sex differentiation in Teleost fishFox tales: regulation of gonadotropin gene expression by forkhead transcription factorsJust how conserved is vertebrate sex determination?MicroRNAs Related to Polycystic Ovary Syndrome (PCOS)Glutamate Cysteine Ligase Modifier Subunit (Gclm) Null Mice Have Increased Ovarian Oxidative Stress and Accelerated Age-Related Ovarian FailureFoxl2, a forkhead transcription factor, modulates nonclassical activity of the estrogen receptor-alphaFSH and FOXO1 regulate genes in the sterol/steroid and lipid biosynthetic pathways in granulosa cellsDMRT1 prevents female reprogramming in the postnatal mammalian testisFoxl2 is required for commitment to ovary differentiationAntagonistic regulation of Cyp26b1 by transcription factors SOX9/SF1 and FOXL2 during gonadal development in miceTrajectories and phenotypes with estrogen exposures across the lifespan: What does Goldilocks have to do with it?The forkhead transcription factor Foxl2 is sumoylated in both human and mouse: sumoylation affects its stability, localization, and activity.The disparate origins of ovarian cancers: pathogenesis and prevention strategies.FOXO1/3 and PTEN Depletion in Granulosa Cells Promotes Ovarian Granulosa Cell Tumor Development.Constitutively active Foxo3 in oocytes preserves ovarian reserve in mice.Impaired fertility and FSH synthesis in gonadotrope-specific Foxl2 knockout miceImpaired FSHbeta expression in the pituitaries of Foxl2 mutant animals.Dysregulation of WNT/CTNNB1 and PI3K/AKT signaling in testicular stromal cells causes granulosa cell tumor of the testisConditional deletion of the retinoblastoma (Rb) gene in ovarian granulosa cells leads to premature ovarian failure.Notch gain of function in mouse periocular mesenchyme downregulates FoxL2 and impairs eyelid levator muscle formation, leading to congenital blepharophimosis.Comparing the DNA hypermethylome with gene mutations in human colorectal cancer.R-spondin1 and FOXL2 act into two distinct cellular types during goat ovarian differentiation.Identification of transcripts involved in meiosis and follicle formation during ovine ovary development.A novel SRY missense mutation affecting nuclear import in a 46,XY female patient with bilateral gonadoblastoma.Foxl2 functions in sex determination and histogenesis throughout mouse ovary development.Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.FOXL2 interacts with steroidogenic factor-1 (SF-1) and represses SF-1-induced CYP17 transcription in granulosa cells.FOXL2 suppresses proliferation, invasion and promotes apoptosis of cervical cancer cellsEx vivo cultures combined with vivo-morpholino induced gene knockdown provide a system to assess the role of WT1 and GATA4 during gonad differentiation.Minireview: Activin Signaling in Gonadotropes: What Does the FOX say… to the SMAD?Pituitary gland development and disease: from stem cell to hormone productionMicroarray analysis of Foxl2 mediated gene regulation in the mouse ovary derived KK1 granulosa cell line: Over-expression of Foxl2 leads to activation of the gonadotropin releasing hormone receptor gene promoter.The ovary: basic biology and clinical implications
P2860
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P2860
Foxl2 disruption causes mouse ovarian failure by pervasive blockage of follicle development
description
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Juni 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/06/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/06/01)
@nl
наукова стаття, опублікована в червні 2004
@uk
مقالة علمية (نشرت في يونيو 2004)
@ar
name
Foxl2 disruption causes mouse ...... ockage of follicle development
@ast
Foxl2 disruption causes mouse ...... ockage of follicle development
@en
Foxl2 disruption causes mouse ...... ockage of follicle development
@nl
type
label
Foxl2 disruption causes mouse ...... ockage of follicle development
@ast
Foxl2 disruption causes mouse ...... ockage of follicle development
@en
Foxl2 disruption causes mouse ...... ockage of follicle development
@nl
prefLabel
Foxl2 disruption causes mouse ...... ockage of follicle development
@ast
Foxl2 disruption causes mouse ...... ockage of follicle development
@en
Foxl2 disruption causes mouse ...... ockage of follicle development
@nl
P50
P3181
P356
P1476
Foxl2 disruption causes mouse ...... ockage of follicle development
@en
P2093
Jose Elias Garcia
Wendy Kimber
P304
P3181
P356
10.1093/HMG/DDH124
P50
P577
2004-06-01T00:00:00Z