BRCA2 deficiency in mice leads to meiotic impairment and infertility
about
Clarifying the mechanics of DNA strand exchange in meiotic recombinationBRCA2 suppresses cell proliferation via stabilizing MAGE-D1Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1Association of BRCA1 mutations with occult primary ovarian insufficiency: a possible explanation for the link between infertility and breast/ovarian cancer risksRPA homologs and ssDNA processing during meiotic recombinationRoles of brca2 (fancd1) in oocyte nuclear architecture, gametogenesis, gonad tumors, and genome stability in zebrafishDSS1 is required for the stability of BRCA2Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosisGenetic evidence suggests that Spata22 is required for the maintenance of Rad51 foci in mammalian meiosisCharacterizing a rat Brca2 knockout modelRAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in femalesMEIOB targets single-strand DNA and is necessary for meiotic recombinationMeiotic cohesin complexes are essential for the formation of the axial element in miceMouse TRIP13/PCH2 is required for recombination and normal higher-order chromosome structure during meiosisHomologs of breast cancer genes in plantsRAD-51-dependent and -independent roles of a Caenorhabditis elegans BRCA2-related protein during DNA double-strand break repair.Suppression of the DNA repair defects of BRCA2-deficient cells with heterologous protein fusions.BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice.BRCA1 and BRCA2 mutations and female fertilityLong human CHGA flanking chromosome 14 sequence required for optimal BAC transgenic "rescue" of disease phenotypes in the mouse Chga knockout.Hypertension from targeted ablation of chromogranin A can be rescued by the human orthologPlasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains.BRCA1 and BRCA2: breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair.BRCA2 is a mediator of RAD51- and DMC1-facilitated homologous recombination in Arabidopsis thaliana.brca2 in zebrafish ovarian development, spermatogenesis, and tumorigenesisFANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis.BRCA2 regulates DMC1-mediated recombination through the BRC repeats.BRCA2: a universal recombinase regulator.Seeking new meiotic genes.The spatial and mechanical challenges of female meiosis.Resolving RAD51C function in late stages of homologous recombinationDearth and Delayed Maturation of Testicular Germ Cells in Fanconi Anemia E Mutant Male MiceHomologous recombination and its regulationMouse models for genes involved in impaired spermatogenesis.Double-stranded DNA breaks and gene functions in recombination and meiosis.Mouse embryonic stem cell-based functional assay to evaluate mutations in BRCA2Sex chromosome inactivation in germ cells: emerging roles of DNA damage response pathways.MRG15 is required for pre-mRNA splicing and spermatogenesis.Brca2 is involved in meiosis in Arabidopsis thaliana as suggested by its interaction with Dmc1.The Fanconi anemia/BRCA gene network in zebrafish: embryonic expression and comparative genomics.
P2860
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P2860
BRCA2 deficiency in mice leads to meiotic impairment and infertility
description
2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Januar 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/01/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/01/01)
@nl
наукова стаття, опублікована в січні 2004
@uk
مقالة علمية (نشرت عام 2004)
@ar
name
BRCA2 deficiency in mice leads to meiotic impairment and infertility
@ast
BRCA2 deficiency in mice leads to meiotic impairment and infertility
@en
BRCA2 deficiency in mice leads to meiotic impairment and infertility
@nl
type
label
BRCA2 deficiency in mice leads to meiotic impairment and infertility
@ast
BRCA2 deficiency in mice leads to meiotic impairment and infertility
@en
BRCA2 deficiency in mice leads to meiotic impairment and infertility
@nl
prefLabel
BRCA2 deficiency in mice leads to meiotic impairment and infertility
@ast
BRCA2 deficiency in mice leads to meiotic impairment and infertility
@en
BRCA2 deficiency in mice leads to meiotic impairment and infertility
@nl
P2093
P3181
P356
P1433
P1476
BRCA2 deficiency in mice leads to meiotic impairment and infertility
@en
P2093
April Pyle
Betty K. Martin
Deborah Swing
Jamie Benedict
Janice Babus
Janice P. Evans
Jodi A. Flaws
Lino Tessarollo
Mary Ann Handel
Shyam K. Sharan
P304
P3181
P356
10.1242/DEV.00888
P407
P577
2004-01-01T00:00:00Z