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Cellular roles of dna topoisomerases: a molecular perspectiveConstruction, characterization, and complementation of a conditional-lethal DNA topoisomerase IIalpha mutant human cell lineNuclear interactions of topoisomerase II alpha and beta with phospholipid scramblase 1Chromosomal variation in neurons of the developing and adult mammalian nervous system(-)-Epigallocatechin gallate, a major constituent of green tea, poisons human type II topoisomerasesBioflavonoids as poisons of human topoisomerase II alpha and II betaTo build a synapse: signaling pathways in neuromuscular junction assemblyDietary polyphenols as topoisomerase II poisons: B ring and C ring substituents determine the mechanism of enzyme-mediated DNA cleavage enhancementCollision of Trapped Topoisomerase 2 with Transcription and Replication: Generation and Repair of DNA Double-Strand Breaks with 5' AdductsMolecular mechanisms of etoposideThe role of muscle-specific tyrosine kinase (MuSK) and mystery of MuSK myasthenia gravisEnhanced etoposide sensitivity following adenovirus-mediated human topoisomerase IIalpha gene transfer is independent of topoisomerase IIbetaLrp4 is a retrograde signal for presynaptic differentiation at neuromuscular synapsesCD24 is expressed by myofiber synaptic nuclei and regulates synaptic transmission.Aberrant lamination in the cerebral cortex of mouse embryos lacking DNA topoisomerase IIbetaReplication-dependent and transcription-dependent mechanisms of DNA double-strand break induction by the topoisomerase 2-targeting drug etoposideNovel DNA topoisomerase IIα inhibitors from combined ligand- and structure-based virtual screeningRegulation of DNA Topoisomerase IIbeta through RNA-dependent association with heterogeneous nuclear ribonucleoprotein U (hnRNP U)p53 Deficiency rescues neuronal apoptosis but not differentiation in DNA polymerase beta-deficient miceDNA topoisomerase II distribution in mouse preimplantation embryosDNA topoisomerase II is essential for preimplantation mouse developmentTopoisomerase IIbeta is required for lamina-specific targeting of retinal ganglion cell axons and dendritesMuscle-wide secretion of a miniaturized form of neural agrin rescues focal neuromuscular innervation in agrin mutant mice.Essential roles of the acetylcholine receptor gamma-subunit in neuromuscular synaptic patterning.A novel role for MuSK and non-canonical Wnt signaling during segmental neural crest cell migration.Initiation of synapse formation by Wnt-induced MuSK endocytosis.Recovery of the poisoned topoisomerase II for DNA religation: coordinated motion of the cleavage core revealed with the microsecond atomistic simulation.Enforced cytokinesis without complete nuclear division in embryonic cells depleting the activity of DNA topoisomerase IIalpha.Development of neuromuscular junctions in the mouse esophagus: morphology suggests a role for enteric coinnervation during maturation of vagal myoneural contacts.Meltrin beta/ADAM19 interacting with EphA4 in developing neural cells participates in formation of the neuromuscular junction.Topoisomerase IIbeta activates a subset of neuronal genes that are repressed in AT-rich genomic environment.Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogueTopoisomerase IIalpha binding domains of adenomatous polyposis coli influence cell cycle progression and aneuploidy.Sensitivity of human type II topoisomerases to DNA damage: stimulation of enzyme-mediated DNA cleavage by abasic, oxidized and alkylated lesionsTOP2β is essential for ovarian follicles that are hypersensitive to chemotherapeutic drugsTransgene-mediated co-suppression of DNA topoisomerase-1 gene in Caenorhabditis elegans.Increased negative supercoiling of mtDNA in TOP1mt knockout mice and presence of topoisomerases IIα and IIβ in vertebrate mitochondria.Organization of synaptic myonuclei by Syne proteins and their role during the formation of the nerve-muscle synapseInduction of multiple signaling loops by MuSK during neuromuscular synapse formation.The use of divalent metal ions by type II topoisomerases.
P2860
Q22121990-A30A4199-D5D1-46E8-8585-B0060A97EAC7Q24305823-85A6984A-2E9B-4BD0-ACF3-DC508388F595Q24310373-2E2AE58A-74D9-4E25-B9EA-B48C0C6EBE57Q24555100-5D787EB1-1D39-4780-87B0-146C721E3C42Q24627296-9E940252-C455-421E-A9F6-030E592A4A75Q24627367-2204F78A-FCA4-43ED-90F7-0B50AEFE37EBQ24631081-15629741-2EAA-48FB-B384-9A15BA73672FQ24642324-DCA0B6D7-CFB2-46B5-AED1-75D247C09439Q26744712-38E69D16-4A55-4DA2-A249-E147A206A85FQ26776299-CCDCB90B-03C2-48E2-A793-6AF3C1D46464Q27008264-C34FB2A8-5926-40C7-A3D8-B5F6335E00E9Q28348262-85E25E57-590F-4FFF-B7A2-5BFA27757C3CQ28507936-192C063A-E889-4240-9DB3-55266BD37C2DQ28508291-F09874FE-C8C6-4FBD-8723-5EFDFFDE5977Q28509730-0CF4CF29-6036-476D-97FE-FE462818A41EQ28534943-6766A86B-2B09-4FC1-A254-B0DC1904A507Q28542613-BB308D35-98B6-444F-812A-A08BAF80392FQ28577107-5A6BBF88-3DC0-4F8A-8E61-8C3164F6231FQ28585654-1C950CC8-0600-4FDF-9C6E-A637C5D58907Q28586945-1045C9AB-9056-4873-BAB1-493ADB70FD02Q28589046-E605B038-4780-46DC-9B1A-FE9DD3F5E4CDQ30466576-A074F5BC-5A1B-470C-844E-1C4A5B033650Q30482979-98ECC0CF-471B-4501-9B94-2F761C967519Q30486262-B95F9E31-AE39-4E03-967A-504D8C17D8F6Q30502383-853FFAE1-61B8-491E-9F6B-27C4D8E8AF81Q30504867-D12B41D8-F7B4-4567-8F68-82B1D1BC706CQ30661486-D7A1BDF9-E451-4690-80E1-D017B32F1432Q30903327-129B4C9F-ACD6-4BA3-B71A-A53D197E0B6DQ33203395-2D126666-A556-4E57-BEC7-AF9A97FE376CQ33373332-7E57A3F8-770C-4607-936A-FFDD99A5A4F3Q33396673-995E392D-D972-4FE6-A460-26DAD7864800Q33398170-D4C5DEB9-1207-49EB-AF5E-BA5573EACB25Q33549689-CBAFC0D9-C554-43EB-873E-5A79C7855561Q33631024-EA38C9CB-AE06-4E25-BB45-5D7A9A64CB1AQ33669250-60AB3AEF-F268-4177-8EFA-C70E4A04F112Q33760468-2EF0FDB9-39B4-4956-95D0-BB4B78C24D77Q33791241-35824C0E-658B-49DC-B22C-8A1537F2E693Q33936976-2DC19898-6E9B-43A2-86C1-5788B5902680Q33952121-73CF0027-F958-438A-AF40-107010201B7CQ34054930-00917380-E53E-40DA-8366-999791C5308D
P2860
description
2000 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 2000
@ast
im Januar 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/01/07)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/01/07)
@nl
наукова стаття, опублікована в січні 2000
@uk
name
DNA topoisomerase IIbeta and neural development
@ast
DNA topoisomerase IIbeta and neural development
@en
DNA topoisomerase IIbeta and neural development
@nl
type
label
DNA topoisomerase IIbeta and neural development
@ast
DNA topoisomerase IIbeta and neural development
@en
DNA topoisomerase IIbeta and neural development
@nl
prefLabel
DNA topoisomerase IIbeta and neural development
@ast
DNA topoisomerase IIbeta and neural development
@en
DNA topoisomerase IIbeta and neural development
@nl
P2093
P3181
P1433
P1476
DNA topoisomerase IIbeta and neural development
@en
P2093
P304
P3181
P356
10.1126/SCIENCE.287.5450.131
P407
P577
2000-01-07T00:00:00Z