Enforced cytokinesis without complete nuclear division in embryonic cells depleting the activity of DNA topoisomerase IIalpha.
about
Construction, characterization, and complementation of a conditional-lethal DNA topoisomerase IIalpha mutant human cell lineNuclear interactions of topoisomerase II alpha and beta with phospholipid scramblase 1c-erbB2 and topoisomerase IIalpha protein expression independently predict poor survival in primary human breast cancer: a retrospective studyTopoisomerase levels determine chemotherapy responsein vitroandin vivoTopoisomerase IIalpha maintains genomic stability through decatenation G(2) checkpoint signalingMitotic catenation is monitored and resolved by a PKCε-regulated pathwayPurification of GidA protein, a novel topoisomerase II inhibitor produced by Streptomyces flavoviridis.Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogueTopoisomerase IIalpha binding domains of adenomatous polyposis coli influence cell cycle progression and aneuploidy.Maternal topoisomerase II alpha, not topoisomerase II beta, enables embryonic development of zebrafish top2a-/- mutants.Depletion of topoisomerase IIalpha leads to shortening of the metaphase interkinetochore distance and abnormal persistence of PICH-coated anaphase threads.Topoisomerase II regulates the maintenance of DNA methylation.Revised genetic requirements for the decatenation G2 checkpoint: the role of ATM.Topoisomerase IIα in chromosome instability and personalized cancer therapy.Target genes of Topoisomerase IIβ regulate neuronal survival and are defined by their chromatin state.Iron chelators with topoisomerase-inhibitory activity and their anticancer applications.Expression dynamics and functional implications of DNA topoisomerase II beta in the brain.Regulation of the catalytic function of topoisomerase II alpha through association with RNAThe why and how of DNA unlinkingConcurrent inhibition of enzymatic activity and NF-Y-mediated transcription of Topoisomerase-IIα by bis-DemethoxyCurcumin in cancer cells.SUMO modification of DNA topoisomerase II: trying to get a CENse of it allTopoisomerase II beta interacts with cohesin and CTCF at topological domain bordersTopoisomerase II alpha is required for embryonic development and liver regeneration in zebrafish.Pharmacogenetics of genes across the doxorubicin pathway.The α isoform of topoisomerase II is required for hypercompaction of mitotic chromosomes in human cells.Topoisomerases and the regulation of neural function.RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylationStudying vertebrate topoisomerase 2 function using a conditional knockdown system in DT40 cells.NK314, a topoisomerase II inhibitor that specifically targets the alpha isoform.C-terminal regions of topoisomerase IIalpha and IIbeta determine isoform-specific functioning of the enzymes in vivo.Hypersensitivity of nonhomologous DNA end-joining mutants to VP-16 and ICRF-193: implications for the repair of topoisomerase II-mediated DNA damage.Genome-Scale Genetic Interactions and Cell Imaging Confirm Cytokinesis as Deleterious to Transient Topoisomerase II Deficiency in Saccharomyces cerevisiae.DNA topoisomerase II is required for the G0-to-S phase transition in Drosophila Schneider cells, but not in yeast.Gene regulation and priming by topoisomerase IIα in embryonic stem cells.TOP2B: The First Thirty Years
P2860
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P2860
Enforced cytokinesis without complete nuclear division in embryonic cells depleting the activity of DNA topoisomerase IIalpha.
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
name
Enforced cytokinesis without c ...... of DNA topoisomerase IIalpha.
@ast
Enforced cytokinesis without c ...... of DNA topoisomerase IIalpha.
@en
type
label
Enforced cytokinesis without c ...... of DNA topoisomerase IIalpha.
@ast
Enforced cytokinesis without c ...... of DNA topoisomerase IIalpha.
@en
prefLabel
Enforced cytokinesis without c ...... of DNA topoisomerase IIalpha.
@ast
Enforced cytokinesis without c ...... of DNA topoisomerase IIalpha.
@en
P2093
P2860
P1433
P1476
Enforced cytokinesis without c ...... of DNA topoisomerase IIalpha.
@en
P2093
Hideki Koyama
Hiroshi Hamamoto
Hiroshi Hirai
Kazuhisa Sekimizu
Masao Kobayashi
Muktadir S Hossain
Nobuyoshi Akimitsu
Noritaka Adachi
Yasuaki Aratani
P2860
P304
P356
10.1046/J.1365-2443.2003.00643.X
P577
2003-04-01T00:00:00Z