Disruption of the guanylyl cyclase-C gene leads to a paradoxical phenotype of viable but heat-stable enterotoxin-resistant mice
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A novel PDZ protein regulates the activity of guanylyl cyclase C, the heat-stable enterotoxin receptorE. coli heat-stable enterotoxin and guanylyl cyclase C: new functions and unsuspected actionsGuanylate cyclase-C/cGMP: an emerging pathway in the regulation of visceral painExpression of the receptor guanylyl cyclase C and its ligands in reproductive tissues of the rat: a potential role for a novel signaling pathway in the epididymisThe cloning and expression of a new guanylyl cyclase orphan receptorCalorie-induced ER stress suppresses uroguanylin satiety signaling in diet-induced obesityGuanylyl cyclase C-induced immunotherapeutic responses opposing tumor metastases without autoimmunity.Intestinal Enteroids Model Guanylate Cyclase C-Dependent Secretion Induced by Heat-Stable Enterotoxins.Effect of E. coli heat-stable enterotoxin on colonic transport in guanylyl cyclase C receptor-deficient mice.IS1414, an Escherichia coli insertion sequence with a heat-stable enterotoxin gene embedded in a transposase-like geneLack of guanylate cyclase C results in increased mortality in mice following liver injury.Novel functions of photoreceptor guanylate cyclases revealed by targeted deletionGuanylin peptides: renal actions mediated by cyclic GMP.Natriuretic and antikaliuretic effects of uroguanylin and prouroguanylin in the ratInhibition of Heat-Stable Toxin-Induced Intestinal Salt and Water Secretion by a Novel Class of Guanylyl Cyclase C Inhibitors.Role for the membrane receptor guanylyl cyclase-C in attention deficiency and hyperactive behavior.Linaclotide - a secretagogue and antihyperalgesic agent - what next?Guanylate cyclase C limits systemic dissemination of a murine enteric pathogen.Bacterial heat-stable enterotoxins: translation of pathogenic peptides into novel targeted diagnostics and therapeutics.A uroguanylin-GUCY2C endocrine axis regulates feeding in mice.Targeted inactivation of the mouse guanylin gene results in altered dynamics of colonic epithelial proliferationMeconium ileus caused by mutations in GUCY2C, encoding the CFTR-activating guanylate cyclase 2CHomeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine.Membrane guanylyl cyclase receptors: an updatePharmacology and clinical potential of guanylyl cyclase C agonists in the treatment of ulcerative colitis.Enterotoxin preconditioning restores calcium-sensing receptor-mediated cytostasis in colon cancer cellsReview of efficacy and safety of laxatives use in geriatricsGuanylyl cyclase structure, function and regulation.Regulation and therapeutic targeting of peptide-activated receptor guanylyl cyclases.GUCY2C ligand replacement to prevent colorectal cancer.Activation of guanylate cyclase C signaling pathway protects intestinal epithelial cells from acute radiation-induced apoptosis.Guanylate cyclase C deficiency causes severe inflammation in a murine model of spontaneous colitisIntestinal cell proliferation and senescence are regulated by receptor guanylyl cyclase C and p21.Heat-stable enterotoxin of enterotoxigenic Escherichia coli as a vaccine targetLinaclotide, a synthetic guanylate cyclase C agonist, for the treatment of functional gastrointestinal disorders associated with constipation.Toxin mediated diarrhea in the 21 century: the pathophysiology of intestinal ion transport in the course of ETEC, V. cholerae and rotavirus infection.Cure and curse: E. coli heat-stable enterotoxin and its receptor guanylyl cyclase CThe multiple and enigmatic roles of guanylyl cyclase C in intestinal homeostasis.Linaclotide, novel therapy for the treatment of chronic idiopathic constipation and constipation-predominant irritable bowel syndrome.Current understanding of guanylin peptides actions.
P2860
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P2860
Disruption of the guanylyl cyclase-C gene leads to a paradoxical phenotype of viable but heat-stable enterotoxin-resistant mice
description
1997 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1997
@ast
im September 1997 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1997/09/15)
@sk
vědecký článek publikovaný v roce 1997
@cs
wetenschappelijk artikel (gepubliceerd op 1997/09/15)
@nl
наукова стаття, опублікована у вересні 1997
@uk
مقالة علمية (نشرت في 15-9-1997)
@ar
name
Disruption of the guanylyl cyc ...... ble enterotoxin-resistant mice
@ast
Disruption of the guanylyl cyc ...... ble enterotoxin-resistant mice
@en
Disruption of the guanylyl cyc ...... ble enterotoxin-resistant mice
@nl
type
label
Disruption of the guanylyl cyc ...... ble enterotoxin-resistant mice
@ast
Disruption of the guanylyl cyc ...... ble enterotoxin-resistant mice
@en
Disruption of the guanylyl cyc ...... ble enterotoxin-resistant mice
@nl
prefLabel
Disruption of the guanylyl cyc ...... ble enterotoxin-resistant mice
@ast
Disruption of the guanylyl cyc ...... ble enterotoxin-resistant mice
@en
Disruption of the guanylyl cyc ...... ble enterotoxin-resistant mice
@nl
P2093
P2860
P3181
P356
P1476
Disruption of the guanylyl cyc ...... ble enterotoxin-resistant mice
@en
P2093
D. L. Garbers
M. J. Lopez
P2860
P304
P3181
P356
10.1172/JCI119683
P407
P577
1997-09-15T00:00:00Z