Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine. - Test2 - elhamkhani - TriplyDB

Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine.

Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine.

http://www.wikidata.org/entity/Q36202841

about

GUCY2C reverse transcriptase PCR to stage pN0 colorectal cancer patients Hepatocyte Growth Factor from a Clinical Perspective: A Pancreatic Cancer Challenge Guanylyl cyclase C as a biomarker in colorectal cancer From Escherichia coli heat-stable enterotoxin to mammalian endogenous guanylin hormones GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrity Antiobesity pharmacotherapy: new drugs and emerging targets Bile acids initiate lineage-addicted gastroesophageal tumorigenesis by suppressing the EGF receptor-AKT axis.Sildenafil normalizes bowel transit in preclinical models of constipation Lack of guanylate cyclase C results in increased mortality in mice following liver injury.Translating colorectal cancer prevention through the guanylyl cyclase C signaling axis.Loss of guanylyl cyclase C (GCC) signaling leads to dysfunctional intestinal barrier The uroguanylin system and human disease.The paracrine hormone for the GUCY2C tumor suppressor, guanylin, is universally lost in colorectal cancer Prosequence switching: an effective strategy to produce biologically active E. coli heat-stable enterotoxin STh.Guanylate cyclase C limits systemic dissemination of a murine enteric pathogen.Bacterial heat-stable enterotoxins: translation of pathogenic peptides into novel targeted diagnostics and therapeutics.A novel CDX2 isoform regulates alternative splicing.A uroguanylin-GUCY2C endocrine axis regulates feeding in mice.Molecular staging individualizing cancer management.Plecanatide and dolcanatide, novel guanylate cyclase-C agonists, ameliorate gastrointestinal inflammation in experimental models of murine colitis.GUCY2C molecular staging personalizes colorectal cancer patient management GUCY2C: at the intersection of obesity and cancer Bardoxolone Methyl Prevents High-Fat Diet-Induced Colon Inflammation in Mice.Pharmacology and clinical potential of guanylyl cyclase C agonists in the treatment of ulcerative colitis.Enterotoxin preconditioning restores calcium-sensing receptor-mediated cytostasis in colon cancer cells Expression of guanylate cyclase-C, guanylin, and uroguanylin is downregulated proportionally to the ulcerative colitis disease activity index.Guanylyl cyclase structure, function and regulation.Regulation and therapeutic targeting of peptide-activated receptor guanylyl cyclases.GUCY2C ligand replacement to prevent colorectal cancer.Guanylyl cyclase C prevents colon cancer metastasis by regulating tumor epithelial cell matrix metalloproteinase-9 Guanylin and uroguanylin are produced by mouse intestinal epithelial cells of columnar and secretory lineage.Intestinal GUCY2C prevents TGF-β secretion coordinating desmoplasia and hyperproliferation in colorectal cancer.Guanylyl cyclase C in colorectal cancer: susceptibility gene and potential therapeutic target.Type 2 cGMP-dependent protein kinase regulates homeostasis by blocking c-Jun N-terminal kinase in the colon epithelium.GCC signaling in colorectal cancer: Is colorectal cancer a paracrine deficiency syndrome?Can colorectal cancer be prevented or treated by oral hormone replacement therapy?The role of cyclic nucleotide signaling pathways in cancer: targets for prevention and treatment Corruption of homeostatic mechanisms in the guanylyl cyclase C signaling pathway underlying colorectal tumorigenesis Radiometallated peptides targeting guanylate cyclase C and the urokinase-type plasminogen activator receptor.cGMP-dependent protein kinases as potential targets for colon cancer prevention and treatment.

P2860

Q24641833-3639A0BE-CACB-4D75-80C4-5EFE0F244581 Q26781273-19A47938-F30D-4D99-905F-37031C09221A Q27011759-7E0B37C0-C788-4EC7-816F-2251BCD6EF7F Q27025808-559CA372-3F52-4F36-B489-AF57034A8018 Q27308895-B945B3D9-45D3-429D-B5D1-D3056B798502 Q30354242-073865D4-8758-46C1-9F45-46A8B999BEEB Q33610075-99ACF6BC-271C-4582-B3A9-8E0AC10E6981 Q33610799-17EDA200-1545-4334-A2E2-C395543F7EA9 Q33647422-6D0E4923-A534-4D13-87A0-68D232F61256 Q33722761-B447FB48-49D7-4B77-A6A8-0E0E3BC20634 Q33816018-92754FB1-FD09-4031-A1FF-09B889B84442 Q34293073-36A589D0-7AB9-4D18-879F-FCBE76C00309 Q34458591-8E4F061C-FC6D-498A-BFCF-EEFFA131D727 Q34966887-64D96D2E-224D-4494-8517-80046498DA25 Q34978181-AD42DAD6-338D-4274-865A-6D7CFDF55945 Q35155933-F68D0955-E51D-486E-AF92-F110255AA092 Q35220948-40E6F28D-B9A3-4535-BF23-C3FEF34B5513 Q35572696-5598EAB5-4C6B-4917-9955-4759FE091B86 Q35854173-83353A33-F2F7-49CB-ACCF-5C77BF140D32 Q36254155-6BB368E6-CA68-426A-9A67-DC74172E7F66 Q36336227-47FA6DDC-3390-427C-A967-E0850EA9DBCC Q36741685-AC850AD2-5D7A-43B6-BC4C-43CDCF73444F Q36756653-723B47B9-F30C-4567-9D38-5E305AEC2D03 Q36790193-A1A46515-3EF8-4250-9C07-D2A6931E39B8 Q36838038-3841EF31-B02F-47B1-A42F-EF26B57BB044 Q36850377-2CEB3CE4-D092-4C6A-8DBA-C502CBA9755F Q36867727-85CE19F8-5680-4456-9F1F-418FFCDD54BD Q36867743-49BB5761-A17E-4DE2-A014-C39DD49C560E Q37146309-AB8C8856-D17C-468A-B3E4-465200441D4E Q37208825-003CEF52-E2D1-4147-BFB2-597FAACA9DBE Q37284644-9E068A9B-C809-4739-AF23-63F82C866E62 Q37337701-9A157E90-E4FA-48C1-A2DC-E786FAFC9C4D Q37486782-FEDBCE77-B8BA-424D-81E9-CDDC838107E5 Q37578804-B54E3641-4DA5-4DDD-9058-A38DA88BD9FF Q37601318-DBEA0C29-7185-4FE2-BF95-22D3A2734EFB Q37659196-4016F872-0795-44D5-9BC3-5D21E8F8451F Q37693485-65311C92-C005-42D1-8BEC-1D46FFDCC3EE Q37769045-66A84E94-3E72-4CCC-85FD-B75F9B43ED36 Q37783622-CBC6756A-0370-4F65-B11A-3E58EC42D8F3 Q37855854-33578381-8FD5-4B16-AE8E-ACDE521732CF

P2860

Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine.

http://www.wikidata.org/entity/Q36202841

description

2007 nî lūn-bûn

@nan

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

2007年论文

@zh

2007年论文

@zh-cn

name

Homeostatic control of the cry ...... ting compartment in intestine.

@ast

Homeostatic control of the cry ...... ting compartment in intestine.

@en

type

label

Homeostatic control of the cry ...... ting compartment in intestine.

@ast

Homeostatic control of the cry ...... ting compartment in intestine.

@en

prefLabel

Homeostatic control of the cry ...... ting compartment in intestine.

@ast

Homeostatic control of the cry ...... ting compartment in intestine.

@en

P1433

Q36202841-7926CAC2-7B5B-4757-A8E9-477CB63320A7

P1476

Q36202841-B93A65EC-C56E-4C74-919E-696AB441E80A

P2093

Q36202841-117149DD-BCF1-4046-BBD7-1ED158F6EC00

Q36202841-43301F09-0D13-4C3E-AA43-B16350BD475E

Q36202841-50D23D60-A46E-4646-820A-2EF57DCEFC22

Q36202841-CEA9BAD4-8529-4782-9442-1D192DC56FAB

Q36202841-FDB62AF9-BA05-40F3-9AF2-9644FA5EC9D1

P2860

Q36202841-017D209B-6BD3-4EBC-A510-E064A803F751

Q36202841-05919CC8-17D0-4317-AC15-5853A93B7610

Q36202841-0A3CBF64-9C92-4596-AAE6-8726A4737B23

Q36202841-0B031914-27CB-454F-AD2E-B3F4FBEBB58A

Q36202841-11E4EB29-9100-4C6F-A2E3-F59F96629CC4

Q36202841-14FB1A07-11A0-4858-979F-883FB653CA6A

Q36202841-157C1AAA-7068-4F1B-B165-D1113A255F9E

Q36202841-1B41AF45-8BB5-4527-AFAB-CD0BCCF20029

Q36202841-1B7A7089-FE17-44F1-95C6-60B3646791F3

Q36202841-24094DCE-C21B-4A4A-AA70-4C3531CC129C

P304

Q36202841-E653EC74-0D70-4A58-A5BA-81FED28E2E00

P31

Q36202841-71C0D1C7-6A0C-4F14-8B0F-DDA332B606E7

P356

Q36202841-FBBA2F04-C1F2-480C-8ED2-55E19BDD8B7E

P407

Q36202841-1DC5346D-FA2D-4E3B-91E8-294F229A6EB3

P433

Q36202841-520ACE2C-B5A1-4821-AECD-D26BF63F92FC

P478

Q36202841-1872C341-F5DB-4F41-AE92-875459C2D64C

P50

Q36202841-67D151F9-DBDA-40E3-B006-E2BC7C455D74

P577

Q36202841-EEBECAF3-8679-4C98-8B08-F170133F2E58

P5875

Q36202841-A93E3ACA-2E09-454C-BC23-9949430E038D

P698

Q36202841-E684EACA-5259-4AA3-904C-2AB1AC8BAF4E

P932

Q36202841-CE9D29BD-61E3-45E2-96BF-C9B566683647

P356

AJPATH.2007.070198

P1433

The American Journal of Pathology

P1476

Homeostatic control of the cry ...... ating compartment in intestine

@en

P2093

Giovanni M Pitari

http://www.w3.org/2001/XMLSchema#string

Inna Chervoneva

http://www.w3.org/2001/XMLSchema#string

Jieru E Lin

http://www.w3.org/2001/XMLSchema#string

Peng Li

http://www.w3.org/2001/XMLSchema#string

Stephanie Schulz

http://www.w3.org/2001/XMLSchema#string

P2860

A Western-style diet induces benign and malignant neoplasms in the colon of normal C57Bl/6 mice

Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation

Lack of guanylyl cyclase C, the receptor for Escherichia coli heat-stable enterotoxin, results in reduced polyp formation and increased apoptosis in the multiple intestinal neoplasia (Min) mouse model

A validated quantitative assay to detect occult micrometastases by reverse transcriptase-polymerase chain reaction of guanylyl cyclase C in patients with colorectal cancer

Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes

Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity

Colorectal cancer in mice genetically deficient in the mucin Muc2

Disruption of the guanylyl cyclase-C gene leads to a paradoxical phenotype of viable but heat-stable enterotoxin-resistant mice

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

Stem cells: attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt

P304

1847-1858

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.2353/AJPATH.2007.070198

http://www.w3.org/2001/XMLSchema#string

P407

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

171

http://www.w3.org/2001/XMLSchema#string

P50

Scott A. Waldman

P577

2007-11-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5871105

http://www.w3.org/2001/XMLSchema#string

P698

17974601

http://www.w3.org/2001/XMLSchema#string

P932

2111108

http://www.w3.org/2001/XMLSchema#string