Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathway
about
The notch regulator MAML1 interacts with p53 and functions as a coactivatorBovine Herpes Virus 1 (BHV-1) and Herpes Simplex Virus Type 1 (HSV-1) Promote Survival of Latently Infected Sensory Neurons, in Part by Inhibiting ApoptosisPostnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic nicheGenome-wide analysis of N1ICD/RBPJ targets in vivo reveals direct transcriptional regulation of Wnt, SHH, and hippo pathway effectors by Notch1Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epitheliumGrowth and folding of the mammalian cerebral cortex: from molecules to malformationsNotch-1 regulates transcription of the epidermal growth factor receptor through p53.Notch1 activation in mice causes arteriovenous malformations phenocopied by ephrinB2 and EphB4 mutants.SOX2 maintains the quiescent progenitor cell state of postnatal retinal Muller glia.Numb family proteins are essential for cardiac morphogenesis and progenitor differentiationA multi-resource data integration approach: identification of candidate genes regulating cell proliferation during neocortical development.Cleft palate is caused by CNS dysfunction in Gad1 and Viaat knockout mice.The contribution of Notch1 to nephron segmentation in the developing kidney is revealed in a sensitized Notch2 background and can be augmented by reducing Mint dosage.Notch signaling functions in lymphatic valve formation.Murine Notch1 is required for lymphatic vascular morphogenesis during developmentNotch signaling is required for the formation of mesangial cells from a stromal mesenchyme precursor during kidney development.Reduced Notch signaling leads to renal cysts and papillary microadenomas.Embryonic expression of cyclooxygenase-2 causes malformations in axial skeleton.A Disintegrin and Metalloprotease 10 in neuronal maturation and gliogenesis during cortex development.HIV-1 Rev-binding protein accelerates cellular uptake of iron to drive Notch-induced T cell leukemogenesis in miceValproic acid activates Notch1 signaling and induces apoptosis in medullary thyroid cancer cellsThe disintegrin/metalloproteinase ADAM10 is essential for the establishment of the brain cortexGamma-secretase-regulated proteolysis of the Notch receptor by mitochondrial intermediate peptidaseInhibition of Notch signaling promotes browning of white adipose tissue and ameliorates obesityNotch signaling differentially regulates Atoh7 and Neurog2 in the distal mouse retina.Morphine modulates mouse hippocampal progenitor cell lineages by upregulating miR-181a level.Generation of anti-Notch antibodies and their application in blocking Notch signalling in neural stem cells.Endocardial to myocardial notch-wnt-bmp axis regulates early heart valve developmentNOTCH1 gain of function in germ cells causes failure of spermatogenesis in male miceSuppression of insulin-like3 receptor reveals the role of β-catenin and Notch signaling in gubernaculum development.A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia.DDR1 receptor tyrosine kinase promotes prosurvival pathway through Notch1 activation.Perturbed neurogenesis in the adult hippocampus associated with presenilin-1 A246E mutation.Molecular profiles of parvalbumin-immunoreactive neurons in the superior temporal cortex in schizophrenia.Persistent expression of activated Notch inhibits corticotrope and melanotrope differentiation and results in dysfunction of the HPA axis.Notch1 controls macrophage recruitment and Notch signaling is activated at sites of endothelial cell anastomosis during retinal angiogenesis in mice.Osteoclast progenitors reside in the peroxisome proliferator-activated receptor γ-expressing bone marrow cell population.Notch receptor regulation of intestinal stem cell homeostasis and crypt regeneration.Restoration of p53 expression in human cancer cell lines upregulates the expression of Notch1: implications for cancer cell fate determination after genotoxic stressThe intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis
P2860
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P2860
Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathway
description
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Mai 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/05/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/05/01)
@nl
наукова стаття, опублікована в травні 2004
@uk
مقالة علمية (نشرت في مايو 2004)
@ar
name
Notch activation induces apopt ...... hrough a p53-dependent pathway
@ast
Notch activation induces apopt ...... hrough a p53-dependent pathway
@en
Notch activation induces apopt ...... hrough a p53-dependent pathway
@nl
type
label
Notch activation induces apopt ...... hrough a p53-dependent pathway
@ast
Notch activation induces apopt ...... hrough a p53-dependent pathway
@en
Notch activation induces apopt ...... hrough a p53-dependent pathway
@nl
prefLabel
Notch activation induces apopt ...... hrough a p53-dependent pathway
@ast
Notch activation induces apopt ...... hrough a p53-dependent pathway
@en
Notch activation induces apopt ...... hrough a p53-dependent pathway
@nl
P2093
P3181
P1476
Notch activation induces apopt ...... hrough a p53-dependent pathway
@en
P2093
Rüdiger Klein
Xiaolin Tian
Xudong Yang
P3181
P356
10.1016/J.YDBIO.2004.01.014
P407
P577
2004-05-01T00:00:00Z