Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways
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PRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12Identification and characterization of a novel lysophosphatidic acid receptor, p2y5/LPA6AKAP13 Rho-GEF and PKD-binding domain deficient mice develop normally but have an abnormal response to β-adrenergic-induced cardiac hypertrophyG proteins G12 and G13 control the dynamic turnover of growth factor-induced dorsal rufflesChanges in global gene expression during in vitro decidualization of rat endometrial stromal cellsA new approach to producing functional G alpha subunits yields the activated and deactivated structures of G alpha(12/13) proteinsS1pr2/Gα13 signaling controls myocardial migration by regulating endoderm convergence.Galpha13 regulates MEF2-dependent gene transcription in endothelial cells: role in angiogenesis.G-protein stimulatory subunit alpha and Gq/11α G-proteins are both required to maintain quiescent stem-like chondrocytes.Polycystin-1 and Gα12 regulate the cleavage of E-cadherin in kidney epithelial cellsResistance to inhibitors of cholinesterase-8A (Ric-8A) is critical for growth factor receptor-induced actin cytoskeletal reorganization.Heterotrimeric G proteins, focal adhesion kinase, and endothelial barrier function.H2O2 activates G protein, α 12 to disrupt the junctional complex and enhance ischemia reperfusion injuryRole of Galpha12 and Galpha13 as novel switches for the activity of Nrf2, a key antioxidative transcription factor.5-HT7R/G12 signaling regulates neuronal morphology and function in an age-dependent manner.G proteins in development.Galpha13 mediates a signal that is essential for proliferation and survival of thymocyte progenitors.Determinants at the N- and C-termini of Gα12 required for activation of Rho-mediated signaling.PDZ-RhoGEF and LARG are essential for embryonic development and provide a link between thrombin and LPA receptors and Rho activationThe gep proto-oncogene Gα13 mediates lysophosphatidic acid-mediated migration of pancreatic cancer cells.Anaphylactic shock depends on endothelial Gq/G11.Atypical protein kinase Cλ is critical for growth factor receptor-induced dorsal ruffle turnover and cell migrationRegulation and physiological functions of G12/13-mediated signaling pathways.Regulation of RhoGEF proteins by G12/13-coupled receptors.Autotaxin/lysophospholipase D-mediated lysophosphatidic acid signaling is required to form distinctive large lysosomes in the visceral endoderm cells of the mouse yolk sac.Suppression of tumor angiogenesis by Galpha(13) haploinsufficiency.Role of G12 proteins in oncogenesis and metastasisGα12 structural determinants of Hsp90 interaction are necessary for serum response element-mediated transcriptional activation.G12/13-dependent signaling of G-protein-coupled receptors: disease context and impact on drug discovery.The regulating function of heterotrimeric G proteins in the immune system.Gα13 is closely related to hematopoiesis in zebrafish.Gα12 gep oncogene deregulation of p53-responsive microRNAs promotes epithelial-mesenchymal transition of hepatocellular carcinoma.Regulation, Signaling, and Physiological Functions of G-Proteins.Role of G Protein-Coupled Receptors in the Regulation of Structural Plasticity and Cognitive Function.Galpha12 specifically regulates COX-2 induction by sphingosine 1-phosphate. Role for JNK-dependent ubiquitination and degradation of IkappaBalpha.Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during developmentGα12 is required for renal cystogenesis induced by Pkd1 inactivation.Succinate promotes stem cell migration through the GPR91-dependent regulation of DRP1-mediated mitochondrial fission.Galpha12/Galpha13 deficiency causes localized overmigration of neurons in the developing cerebral and cerebellar cortices.Galpha13 stimulates cell migration through cortactin-interacting protein Hax-1.
P2860
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P2860
Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways
description
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2002
@ast
im Juli 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/07/09)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/07/09)
@nl
наукова стаття, опублікована в липні 2002
@uk
name
Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways
@ast
Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways
@en
Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways
@nl
type
label
Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways
@ast
Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways
@en
Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways
@nl
prefLabel
Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways
@ast
Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways
@en
Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways
@nl
P2093
P2860
P921
P356
P1476
Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways
@en
P2093
Jennifer L. Gu
Melvin I. Simon
Stefan Müller
Valeria Mancino
P2860
P304
P356
10.1073/PNAS.102291599
P407
P577
2002-07-09T00:00:00Z