Mouse mutants from chemically mutagenized embryonic stem cells
about
Embryonic stem cells and somatic cells differ in mutation frequency and typeMouse genetic and phenotypic resources for human geneticsEfficient gene-driven germ-line point mutagenesis of C57BL/6J miceVestibular defects in head-tilt mice result from mutations in Nox3, encoding an NADPH oxidasePositional cloning and characterization of Mei1, a vertebrate-specific gene required for normal meiotic chromosome synapsis in miceENU induced single mutation locus on chr 16 leads to high-frequency hearing loss in miceAn allelic series of mutations in Smad2 and Smad4 identified in a genotype-based screen of N-ethyl-N- nitrosourea-mutagenized mouse embryonic stem cells.Chemical genetics: ligand-based discovery of gene function.Expression and loss of alleles in cultured mouse embryonic fibroblasts and stem cells carrying allelic fluorescent protein genes.A dominant, recombination-defective allele of Dmc1 causing male-specific sterility.The expanding role of mouse genetics for understanding human biology and diseaseA homozygous mutant embryonic stem cell bank applicable for phenotype-driven genetic screening.A high throughput genetic screen identifies new early meiotic recombination functions in Arabidopsis thalianaTransmission of mutant phenotypes from ES cells to adult mice.Development of an enhanced GFP-based dual-color reporter to facilitate genetic screens for the recovery of mutations in miceInner ear proteomics of mouse models for deafness, a discovery strategy.N-ethyl-N-nitrosourea mutagenesis: boarding the mouse mutant express.Transgenic gene knock-outs: functional genomics and therapeutic target selection.Chromatin remodeling, DNA damage repair and aging.Mutation rate and predicted phenotypic target sizes in ethylnitrosourea-treated mice.DNA repair: the culprit for tumor-initiating cell survival?Mechanism and regulation of meiotic recombination initiation.Evidence Implicating CCNB1IP1, a RING Domain-Containing Protein Required for Meiotic Crossing Over in Mice, as an E3 SUMO Ligase.Moving forward with chemical mutagenesis in the mouse.Exploring the elephant: histopathology in high-throughput phenotyping of mutant mice.Kif18a is specifically required for mitotic progression during germ line development.Mouse models for genes involved in impaired spermatogenesis.Fast forward to new genes in mammalian reproduction.LIG4 mediates Wnt signalling-induced radioresistance.DNA repair in murine embryonic stem cells and differentiated cellsRandom mutagenesis of the mouse genome: a strategy for discovering gene function and the molecular basis of disease.Human induced pluripotent cells resemble embryonic stem cells demonstrating enhanced levels of DNA repair and efficacy of nonhomologous end-joining.Initiation of meiotic recombination in mammals.Pathology of the laboratory mouse: an International Workshop on Challenges for High Throughput Phenotyping.Mechanisms maintaining genomic integrity in embryonic stem cells and induced pluripotent stem cellsGenetic instability in human embryonic stem cells: prospects and caveats.An improved cryopreservation method for a mouse embryonic stem cell lineSlingshot: a PiggyBac based transposon system for tamoxifen-inducible 'self-inactivating' insertional mutagenesis.Efficient biallelic mutagenesis with Cre/loxP-mediated inter-chromosomal recombinationMolecular characterization of an allelic series of mutations in the mouse Nox3 gene
P2860
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P2860
Mouse mutants from chemically mutagenized embryonic stem cells
description
2000 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մարտին հրատարակված գիտական հոդված
@hy
articolo scientifico
@it
artículu científicu espublizáu en 2000
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im März 2000 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2000/03/01)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/03/01)
@nl
наукова стаття, опублікована в березні 2000
@uk
name
Mouse mutants from chemically mutagenized embryonic stem cells
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Mouse mutants from chemically mutagenized embryonic stem cells
@en
Mouse mutants from chemically mutagenized embryonic stem cells
@nl
type
label
Mouse mutants from chemically mutagenized embryonic stem cells
@ast
Mouse mutants from chemically mutagenized embryonic stem cells
@en
Mouse mutants from chemically mutagenized embryonic stem cells
@nl
prefLabel
Mouse mutants from chemically mutagenized embryonic stem cells
@ast
Mouse mutants from chemically mutagenized embryonic stem cells
@en
Mouse mutants from chemically mutagenized embryonic stem cells
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Mouse mutants from chemically mutagenized embryonic stem cells
@en
P2093
J. C. Schimenti
K. J. Schimenti
Q. Y. Zheng
R. A. Bergstrom
R. J. Munroe
S. W. John
V. L. Browning
P2860
P2888
P304
P3181
P356
10.1038/73563
P407
P577
2000-03-01T00:00:00Z
P5875
P6179
1013355710