Decoding hematopoietic specificity in the helix-loop-helix domain of the transcription factor SCL/Tal-1
about
LMO4 controls the balance between excitatory and inhibitory spinal V2 interneuronsStructural Basis for LMO2-Driven Recruitment of the SCL:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional TargetsSpecification of astrocytes by bHLH protein SCL in a restricted region of the neural tubeAngiopoietin-2 is a direct transcriptional target of TAL1, LYL1 and LMO2 in endothelial cellsMll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reassignment in tumorigenesisSCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cellsTAL-1/SCL and its partners E47 and LMO2 up-regulate VE-cadherin expression in endothelial cells.LMO2 Oncoprotein Stability in T-Cell Leukemia Requires Direct LDB1 Binding.Concise review: Blood relatives: formation and regulation of hematopoietic stem cells by the basic helix-loop-helix transcription factors stem cell leukemia and lymphoblastic leukemia-derived sequence 1.ETO-2 associates with SCL in erythroid cells and megakaryocytes and provides repressor functions in erythropoiesis.Purification, crystallization and preliminary X-ray analysis of a fusion of the LIM domains of LMO2 and the LID domain of Ldb1.LMO2 is required for TAL1 DNA binding activity and initiation of definitive haematopoiesis at the haemangioblast stage.Protein stability and transcription factor complex assembly determined by the SCL-LMO2 interaction.A DNA-binding mutant of TAL1 cooperates with LMO2 to cause T cell leukemia in mice.
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P2860
Decoding hematopoietic specificity in the helix-loop-helix domain of the transcription factor SCL/Tal-1
description
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
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im September 2004 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2004/09/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/09/01)
@nl
наукова стаття, опублікована у вересні 2004
@uk
مقالة علمية (نشرت في سبتمبر 2004)
@ar
name
Decoding hematopoietic specifi ...... transcription factor SCL/Tal-1
@ast
Decoding hematopoietic specifi ...... transcription factor SCL/Tal-1
@en
Decoding hematopoietic specifi ...... transcription factor SCL/Tal-1
@nl
type
label
Decoding hematopoietic specifi ...... transcription factor SCL/Tal-1
@ast
Decoding hematopoietic specifi ...... transcription factor SCL/Tal-1
@en
Decoding hematopoietic specifi ...... transcription factor SCL/Tal-1
@nl
prefLabel
Decoding hematopoietic specifi ...... transcription factor SCL/Tal-1
@ast
Decoding hematopoietic specifi ...... transcription factor SCL/Tal-1
@en
Decoding hematopoietic specifi ...... transcription factor SCL/Tal-1
@nl
P2093
P2860
P1476
Decoding hematopoietic specifi ...... transcription factor SCL/Tal-1
@en
P2093
Andreas Fisher
Anna Schuh
Catherine Porcher
Hanna Mikkola
Simon Flitter
Stuart H. Orkin
Thorsten M. Schlaeger
P2860
P304
P356
10.1128/MCB.24.17.7491-7502.2004
P407
P50
P577
2004-09-01T00:00:00Z